Drugs for Heart Failure Flashcards

1
Q

4 classes of Drugs for HF

A
  1. Inotropics
  2. Vasodilators (ACEIs, ARBs, Hydralazine, Nitrates)
  3. Diuretics
  4. Beta blockers
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2
Q

Digoxin
Inamrinone & Milrinone
Dopamine & Dobutamine

A

Inotropics

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3
Q

What ion in involved in heart contractility
(inotropy)?

A

Calcium (use: management for CHF)

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4
Q

MOA: (-) Na/K/ATPase pump

A

Digoxin

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5
Q

MOA: ↑ (-) PDE3 = ↑ cAMP

A

Inamrinone & Milrinone

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6
Q

MOA: (+) β1 = ↑ inotropy

A

Dopamine & Dobutamine

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7
Q

First-line drugs for CHF

A

ACEIs or ARBs
If NOT tolerated: Hydralazine & Nitrates

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8
Q

First-line in CHF with atrial fibrillation

A

Digoxin

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9
Q

Drugs that slow cardiac remodeling

A

ARBs
ACEIs
B-blockers
Spironolactone

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