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M4: Pharmacology-Pharmacokinetics > Anxiolytic Agents > Flashcards

Anxiolytic Agents Flashcards

1
Q

Inc. catecholamine,
Dec. serotonin (sadness)

A

Anxiety

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2
Q

Bridge Drugs for Anxiety

A

BZD

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3
Q

1st line for Panic disorder

A

SSRIs

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4
Q

Generalized anxiety disorder

A

SSRIs (Fluoxetine)
SNRIs (Duloxetine)
Buspirone (for unresponsive)

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5
Q

Obsessive-compulsive disorder (OCD)

A

SSRIs

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6
Q

Social anxiety disorder &
Post-traumatic stress disorder

A

1st line tx: CBT
1st line Drug: SSRIs

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7
Q

MOA: ↑ the FREQUENCY of Cl- channel opening

A

BZD

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8
Q

MOA: ↑ the DURATION of Cl- channel opening
- more toxic

A

Barbiturates

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9
Q

1st-line drugs for insomnia

A

Sleeping onset: Zaleplon (or Ramelteon)
Staying asleep: Zolpidem (or Eszopiclone)

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10
Q

Phenobarbital is an

A

Enzyme InDucer

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11
Q

Active metabolite of chloral hydrate

A

Trichloroethanol

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12
Q

Anterograde amnesia ‘‘date rape’’

A

Benzodiazepines (e.g., Flunitrazepam and
Midazolam)

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M4: Pharmacology-Pharmacokinetics (50 decks)

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