Fungal infections

Question 1

Treatment of oesophageal candidiasis

Answer 1

Fluconazole

Question 2

Treatment or oropharyngeal candidiasis

Answer 2

Oral clotrimazole
Oral nystat

Question 3

Treatment of systemic candidiasis

Answer 3

IV amphotericin B

Question 4

Treatment of invasive aspergillosis

Answer 4

Voriconazole
Caspofungin
IV amphotericin B

Question 5

Treatment of cryptococcosis

Answer 5

IV amphotericin B + flucytosine (in first 2 weeks)
Oral fluconazole (after 2 weeks)

Question 6

Treatment of blastomycosis

Answer 6

Oral itraconazole/fluconazole
Severe - IV amphotericin B

Question 7

Treatment of histoplasmosis

Answer 7

Oral itraconazole/fluconazole
Severe - IV amphotericin B

Question 8

Treatment of coccidioidomycosis

Answer 8

Oral itraconazole/fluconazole
Severe - IV amphotericin B

Question 9

Treatment of sporotrichosis

Answer 9

Oral itraconazole/fluconazole
Severe - IV amphotericin B

Question 10

Treatment of dermatophytosis

Answer 10

Topical ciclopirox
Topical azoles
Oral itraconazole
Oral griseofulvin
Terbinafine - onychomycosis

Question 11

Treatment for candida glabrata

Answer 11

Usually resistant to fluconazole
Echinocandins preferred treatment

Question 12

Treatment for candida auris

Answer 12

High levels of antifungal resistance
Resistant to azoles in 90% of cases, amphotericin in 30% of cases

Requires echinocandin therapy