Form 6

Question 1

Alcoholic hepatitis labs

Answer 1

ASTx2 > ALT
↑ GGT
↑ Ferretin

Question 2

Ferritin

Answer 2

acute phase reactant

binds/ sequesters iron to inhibit microbial iron scavenging

Question 3

Rx for social anxiety

Answer 3

SSRI

BB for “performance” anxiety

Question 4

Family members of pertussis pt

Answer 4

recieve macrolides

Question 5

Neonatal polycythemia s/s

Answer 5

HCT > 65%
resp distress
hypoglycemia
neuro

Question 6

What is wrong in Bruton

Answer 6

no B cells
Recurrent bacterial infections
↓ Ig of all classes

Question 7

Selective IgA

deficiency

Answer 7

Most common 1°
immunodeficiency

↓ IgA with normal IgG, IgM levels.

Asymptomatic.
Can see Airway and GI infections, Autoimmune
disease, Anaphylaxis to IgA-containing products.

Question 8

Common variable

immunodeficiency

Answer 8

Defect in B-cell differentiation

↓ plasma cells
↓ immunoglobulins

Question 9

hyper-IgE syndrome

Answer 9

Job syndrome

impaired
recruitment of neutrophils to
sites of infection

↑ IgE, ↓ IFN-γ.

Question 10

Hyper-IgM syndrome

Answer 10

defective CD40L on Th cells ↓ class switching 
X-linked 

Severe pyogenic infections
early in life; opportunistic
infection with Pneumocystis,
Cryptosporidium, CMV.

Normal or ↑ IgM.
↓↓↓ IgG, IgA, IgE.

Question 11

Wiskott-Aldrich

syndrome

Answer 11

T cells cant reorganize actin cytoskeleton

WATER: Wiskott-Aldrich: Thrombocytopenia, Eczema, Recurrent infections

↑ IgE, IgA.
↓ / normal IgG, IgM.

Question 12

Chédiak-Higashi

syndrome

Answer 12

Microtubule dysfunction in
phagosome-lysosome fusion

Recurrent infections by staph and strept,
albinism, peripheral
neuropathy, neurodegeneration, infiltrative lymphohistiocytosis.

Question 13

Chronic
granulomatous
disease

Answer 13

Defect of NADPH oxidase–> ↓ reactive oxygen
and ↓ respiratory burst
in pmns

↑ susceptibility to Catalase
⊕ organisms

Abnormal dihydrorhodamine and Nitroblue tetrazolium tests

Question 14

Catalase

⊕ organisms

Answer 14

Nocardia
Pseudomonas Listeria
Aspergillus
Candida
E coli
Staph
Serratia,
H pylori

Question 15

Encapsulated ⊕ organisms

Answer 15

• Pseudomonas
• Strept pneumo
• Hib
• N meningitidis
• E coli
• Salmonella
• Klebsiella
• group B Strep

Question 16

Leukocyte adhesion

deficiency

Answer 16

↑ neutrophils.
Absence of neutrophils at
infection sites

Recurrent bacterial skin and
mucosal infections, absent pus formation

Question 17

DDX of pseudogout, also screen for?

Answer 17

hemochromatosis

Question 18

Arrest of second stage of labor

Answer 18

no fetal decent after:
2 hours in G+
3 hours in nullipari

Question 19

Dermatitis herpetiformis

Answer 19

deposits of IgA in skin
asc w/ celiac
rx: dapsone

Question 20

Dapsone

Answer 20

similar to sulfomamides (SMX)
used in leprosey, profylaxisis to PCP, and dermatitis herpetiformis

s/e: G6PD hemolysis

Question 21

Continuous machine-like murmur. Loudest at S2.

Answer 21

Patent ductus arteriosus

may have: Recurrent URI, “to-and-fro murmur” loud S2, bounding peripheral pulses, widened pulse pressure

Question 22

a to and fro murmur means?

Answer 22

continuous

Question 23

Tetralogy of Fallot parts

Answer 23

1- Pulmonary stenosis
2- RVH
3- Overriding aorta
4- VSD

Squatting: ↑ SVR, ↓ R -> L shunt, improves cyanosis.
rx: early surgical correction.

Question 24

Hyaline casts

Answer 24

Nonspecific, can be a normal finding, often seen in concentrated urine samples

Question 25

Waxy casts

Answer 25

End-stage renal disease/chronic renal failure

Question 26

Fatty casts

Answer 26

Nephrotic syndrome.

Question 27

Systolic ejection murmur, Ejection click

Answer 27

Aortic stenosis

Question 28

Rheumatic heart disease is most likely to cause?

Answer 28

Mitral valve stenosis

Question 29

Late systolic crescendo murmur with midsystolic click

Answer 29

Mitral valve prolapse

Question 30

Opening snap, Delayed rumbling late diastolic murmur

Answer 30

Mitral stenosis

Question 31

Basilar artery stroke would result in?

Answer 31

locked in syndrome

Question 32

Lenticulostriate

artery supplies?

Answer 32

Striatum, internal capsule