And the story goes Flashcards
congenital rubella s/s
mom w/ arthritic virus in prego
baby w/ sensorineural hearing loss, cardiac defects, cataracts
ddx by infant IgM
congenital varicella s/s
limb hypoplasia
cataracts
skin scarring
rapidly progressive glomerulonephritis light microscopy
crescent formation
PKU
deficiency of phenylalanine hydroxylase
fair, musty, intellectual disability, eczema
rx: low phenylalanine diet
Aldolase B deficiency
hereditary fructose intolerance
NVD, lethargy, sz after introduction of F/V
Diabetic nephropathy on light microscopy
hyalinosis of afferent/ efferent arterioles
wiskott aldrich
x-linked
thrombocytopenia, eczema, recurrent infections
problem with cytoskeletal regulation
wiskott aldrich rx
stem cell transplant
________ are effective for the depressive phase of bipolar (not Li)
second generation antipsychotics
Imipramine moa
tri-cyclic
Citalopram moa
SSRI
galacosemia
presents in first days of life after breast milk/ formula
jaundice, hepatomegaly, failure to thrive
Congenital hypothyroid s/s
large fontanel
failure to thrive
hypotonia
Linear deposits on immunofluorescence
Goodpasture’s
anti-GBM antibody
Granular deposits on immunofluorescence
immune-complex
- SLE
- IgA
- post-infectious
Two most common causes of amyloidosis
Multiple myeloma- light chain
RA- abnormal protein
Hand, foot, and mouth syndrome
caused by coxsackie virus vesicular rash (hand foot and mouth)
Pertussis and CBC
shows a lymphocytosis
Most common cause of ventilator pneumonia
Pseudomonas E-coli Klebsiella MRSA Strep
nitroprusside drip can be concerning for?
cyanide toxicity
- HA
- AMS
- Arrhythmias
- Flushing
- Resp depression
In the work up for idiopathic thrombocytopenic purpura, everyone should be tested for ________ infections?
HIV
Hep c
these can mimic the thrombocytopenia
Rx for lyme disease in kids under 8
amoxicillin
- also for pregos
Bacillary angiomatosis
caused by bartonella
red, friable, firm nodules
Most common bug in IV drug use infective endocarditis
S Aureus
*common to embolize to lung and make cavitating lesions
Phlegmasia cerulea dolens
severe DVT, extensive thrombotic occlusion
sudden severe pain, swelling, cyanosis and edema of the affected limb
Felty syndrome CBC
characterized by the triad of RA, splenomegaly, and granulocytopenia.
Neutropenia with large granular lymphocytosis (LGL), also known as pseudo-Felty syndrome
Thiazides side effects
Blocks NaCl trasport
- hypokalemic metabolic alkalosis
- hyponatremia
- hyperGlycemia,
- hyperLipidemia
- hyperUricemia,
- hyperCalcemia.
- sulfa allergy.
Polycythemia Vera
bone marrow tumor
makes too many red cells (can also do other lines)
s/s itching, burning pain in the hands or feet, discoloration of the skin, arthritis
Mupirocin
Bactroban
topical antibiotic
