Fluids + Electrolytes + Acid-Base Balance Flashcards
describe FLUIDS; where are they found?
- they are INTERNAL and surround our cells and are INSIDE our cells
- contain ELECTROLYTES
- water that contains DISSOLVED or SUSPENDED SUBSTANCES
(ex. glucose, mineral salts, or proteins)
what do ELECTROLYTES have?
they have a SPECIFIC DEGREE OF ACIDITY
what must be keep in balance within the body?
- our FLUID, ELECTROLYTE and ACID-BASE BALANCES
- helped to maintain proper FUNCTION in our body systems
what are the FOUR CHARACTERISTICS of body fluids that must be considered?
- FLUID AMOUNT (VOLUME)
- CONCENTRATION (OSMOLALITY)
- COMPOSITION (ELECTROLYTE CONCENTRATION)
- DEGREE OF ACIDITY (pH)
**each of these characteristics are what is needed for BALANCE of normal cellular function
describe WATER
- takes a SIGNIFICANT AMOUNT of body weight (around 60% – lowers to 50% as we age)
- WOMEN have lower water content
- OBESE patients have lower water content
**fat contains less water vs. muscle
describe the TWO DISTINCT COMPARTMENTS of fluid
- EXTRACELLULAR FLUID
the fluid that is OUTSIDE the cells
- takes up around 1/3 of total body water - INTRACELLULAR FLUID
the fluid that is INSIDE the cells
- takes up around 2/3 of total body water
describe the MAJOR DIVISIONS of EXTRACELLULAR FLUID
- INTRAVASCULAR FLUID
- the liquid part of the blood; blood plasma - INTERSTITIAL FLUID
- the fluid located between cells & is outside the blood vessels - TRANSCELLULAR FLUIDS
- csf fluids, synovial fluids, pleural, cerebrospinal fluids
definition of ELECTROLYTES
compound that begins to separate into IONS (specific CHARGED PARTICLES) when dissolved in water
- can be either be POSITIVE (CATION) or NEGATIVE (ANION)
what are our typical POSITIVELY CHARGED CATIONS?
- sodium (Na+)
- potassium (K+)
- calcium (Ca2+)
- magnesium (Mg2+)
what are our typical NEGATIVELY CHARGED ANIONS?
- chloride (Cl-)
- bicarbonate (HCO3-)
what happens if we COMBINE CATIONS and ANIONS?
they create SALTS!
ex. NaCl - when dissolved in water–separate into Na and Cl
definition of OSMOLALITY
the number of CONCENTRATION of SOLUTES in water; very important for IV fluids
- can define how particles PASS through CELL MEMBRANES; either with ease or difficulty–this is known as the fluid’s TONICITY
**aka EFFECTIVE CONCENTRATION/the ability to gain or lose water
what type of TONICITY TYPES can we have?
- ISOTONIC
around 0.9% ; has the same tonicity as blood; no changes to cell - HYPERTONIC
has HIGHER TONICITY as BLOOD **causes cell to SHRINK - HYPOTONIC
has LOWER TONICITY as blood **causes cell to GAIN VOLUME
describe pH scale
scale goes from 0 -14
normal blood pH;
7.35 - 7.45
less than 7.35;
considered ACIDIC
more than 7.45;
considered BASIC/ALKALINE
how do we LOSE FLUID?
can either have SENsible or NONsensible fluid loss
SENSIBLE FLUID LOSS;
can see visible fluid loss (ex. urine)
NONSENSIBLE FLUID LOSS;
cannot see visible fluid loss (ex. respirations or sweating)
what are the MOVEMENT PROCESSES of water & electrolytes?
- ACTIVE TRANSPORT
- DIFFUSION
- OSMOSIS
- FILTRATION
each process is important for maintaining EQUAL OSMOLALITY in all compartments
describe ACTIVE TRANSPORT
- helps to maintain INTRACELLULAR ELECTROLYTE CONCENTRATION
- requires ATP (energy) to move ELECTROLYTES against the CONCENTRATION GRADIENT (lower conc –> higher conc.)
ex. sodium-potassium pump
describe DIFFUSION
- the PASSIVE MOVEMENT of electrolytes - or other particles DOWN a CONCENTRATION GRADIENT
- **opposite direction than ACTIVE TRANSPORT
- requires PROTEINS to work as an ION CHANNEL (very strict regulation + important for muscle & nerve fxn.)
describe OSMOSIS
specific to MOVEMENT OF WATER; moving through cell membrane that separates fluids with DIFFERENT particle concentrations
(lower conc. to higher conc.)
describe FILTRATION
describes fluid movement going in and out; use of HYDROSTATIC PRESSURE
how do we get our FLUID INTAKE?
- from regular DRINKING or EATING
- IV fluids
- RECTAL (enema)
- around ~2300 mL per day
how is FLUID DISTRIBUTED?
- OSMOSIS; distributes between the ECF & ICF
- FILTRATION; distributes between the intravascular and interstitial fluids