Final Exam: Adrenal Gland 2 Flashcards
What is the Middle zone of the adrenal gland, and what does it produce?
Zona Fasiculata- cortisol
What from the Adenohypophysis stimulates cortisol secretion?
ACTH
WHat is CRF?
Corticotropin releasing factor
released from hypothalamus that controls release of ACTH from the adenohypophysis to stimulate cortisol secretion
Where are cortisol receptors found?
cytosol
What are 6 effects of cortisol on carbohydrate metabolism?
- Stimulates synthesis of enzymes for gluconeogenesis during stress
- mobilization of AA from m.
- Antagonizes insulin effects to inhibit gluconeogenesis in liver
- dec. glucose utilization by cells
- potentiates action of glucagon and epi. on glucose metb.
- can cause diabetes mellitus
What are 2 effects of cortisol on protein metabolism?
- reduces cellular protein
2. inc liver plasma proteins
What are the 2 effects of cortisol on fat metabolism?
- inc. mobilization of FA in adipose tissue
2. can cause obesity
T/F. cortisol has immunosuppressive and anti-inflammatoy effects
T
What is the innermost zone of the adrenal cortex and what does it produce?
zona reticularis- androgens
What regulates adrogen production from the zona reticularis?
ACTH
What is produced in the adrenal medulla?
Catecholamines - Epinephrine
What cells in the adrenal medulla produce catecholamines
chromaffin cells
What neurotransmitter initiates the release of catecholamines
acetylcholine
involved in the regulation of intermediary metobolism and responses that allow animals to adjust to situations involving acute stress.
catecholamines
What are the 2 major types of catecholamine receptors?
- Alfa 1 and 2
2. Beta 1 and 2
