Exam II: Estrous Cycle Flashcards
What are the 2 parts of the ovary
- cortex
2. medulla
Which part of the ovary do follicles develop
cortex
What are the stages of follicular development?
- primordial follicle
- primary follicle
- secondary follicle
- antral follicle
- Primordial follicle
- Committed follicle
oocyte surrounded by a single layer of squamous cells
Primordial follicle
Oocyte surrounded by a single layer of cuboidal cells
Primary follicle
OOcyte surrounded by two or more layers
Secondary follicle
Which follicle contains the zona pellucida
Secondary follicle
Which stage of follicle formation has a fluid filled cavity
Antral follicle
Which stage of follicle formation is the origin of oocytes and granulosa cells?
Primordial follicle
Which stage of folliculogenesis contains 20-30 Follicles growing each day?
Committed follicle
Is the committed follicle GnrH Dependent or independent?
Independent
Pool of inactive primordial follicles
Resting pool
once a follicle commences development from the resting pool it is known as:
Committed follicle
Follicular development up to development of ______ is independent of FSH or LH.
Antrum
Connective tissue of the antral follicle
theca externa
3 components of the antral follicle
- Theca externa
- Theca interna
- Granulosa cells
Part of the antral follicle that produces androgens under LH stimulation
Theca Interna
Part of Antral follicle that produces estrogen, inhibin, and follicular fluid, and is responsive to FSH.
Granulosa cells
Structure left immediately after ovulation
Corpus hemorrhagicum
Theca interna and granulosa cells proliferate to fill the cavity, differentiate into luteal cells, and produce progesterone
Corpus luteum (CL)
Cells of the CL that form from Granulosa cells and secrete oxytocin and relaxin
Large luteal cells
Remnant of old corpus luteum
Corpus albicans
Ovarian follicles become gonadotrophin dependent at which stage?
a. Primordial
b. Primary
c. Secondary
d. Antral
d. antral
What are the 3 centers of the Hypothalamus?
- Tonic GnRH center
- Surge Center
- Paraventricular nucleus
Center of the hypothalamus that is responsible for bursts of GnRH required to achieve preovulatory LH surge.
Surge center
In which center of the hypothalamus is oxytocin synthesized?
Paraventricular nucleus
T/F. GnRH affects the anterior pituitary directly.
T
What are the 7 effects of Estrogen?
- Thickening of vag. mucosa
- Mucus secretion
- Epithelial mitosis in endometrium
- Inc. secretory and ciliary beat activity in tubule cells
- Endometrial edema
- Myometrial activity
- Estrous behavior
What 4 things contribute to ovulation
- LH surge
- Theca interna cells produce progesterone rather than androstenedione
- collagenase
- prostaglandins
Progesterone is produced by:
a. the ovarian follicle
b. The corpus luteum
c. The endometrium
d. The hypothalamus
e. The pituitary
b. The CL
What are the 3 effects of progesterone?
- inc. endometrial secretion
- Reduced myometrial activity
- Priming effect in brain to enhance effects of estrogen
The structural and functional degradation of the CL that occurs at the end of the luteal phase in the absence of pregnancy
Luteolysis
What hormones cause Luteolysis?
PGF2a from endometrium
oxytocin
Which species have ipsilateral luteolysis
Ruminants
Which species have systemic luteolysis
mare and sow
Which species have both systemic and counter-current luteolysis
camelids
what is melatonin synthesized from?
tryptophan
Melatonin inc/dec GnRH release in short day breeders
Inc.
Example of short day breeders
Sm. ruminants
Melatonin inc/dec GnRH release in long day breeders
Dec.
Example of long day breeders
Horse
The acquisition of capability of sexual repro.
Puberty
T/F. Puberty and sexual maturation are the same thing
F
T/F. The pulse generator is dormant in juveniles
T
_____ and _____have a negative effect on GnRH release and pulsatility
GABA
NPY - Neuropeptide Y
____ has a positive effect on GnRH signaling and is a mediator of GnRH signaling
Kisspeptin
Adipocyte hormone that can precipitate puberty
Leptin
T/F. inc. leptin may mediate onset of puberty
T
What causes the preovulatory GnRH surge?
Positive feedback of estradiol
T/F Melatonin in sheep inc. GnRH secretion
T
Period from the begining of one estrus to the begining of the next
Estrous cycle
What are the 3 phases of the estrous cycle?
- Follicular phase
- luteal phase
- Quiescent phase (anestrus)
T/F. Estrus is defined hormonally?
F. Behaviorally
What 3 ways can you classify Estrous cycles based on cycle length
- polyestrous
- Monestrous
- Seasonally polyestrous
What two ways can you classify estrous cycles based on ovulation
- spontaneous ovulators
2. induced ovulators
What type of estrous and ovulation cycle do cows have?
Polyestrous, Spontaneous ovulators
What type of estrous and ovulation cycle do dogs have?
Monestrous, spontaneous ovulators
What type of estrous and ovulation cycle do horses have>
Seasonally polyestrous
spontaneous ovulators
What type of estrous and ovulation cycle do sheep have?
seasonally polyestrous
spontaneous ovulators
What are the two categories of seasonally polyestrus animals
short day breeders (fall)
long day breeders (spring)
What are the 2 phases of the follicular phase of the ovarian cycle?
- proestrus
2. estrus
What is occuring during the follicular phase of the ovarian cycle?
Developing follicles
What hormones dominates the follicular phase of the ovarian cycle?
Estrogen
What does the luteal phase of the ovarian cycle encompass?
From ovulation to CL regression
What hormone dominates the luteal phase of the ovarian cycle?
Progesterone
How long is the estrous cycle in a cow
21 days
what are the 4 phases of the estrous cycle in cows
proestrus
estrus
metestrus
diestrus
Signs of estrus in cow
- standing to be mounted
- inc. activity
- dec. milk yeild
- clear vaginal mucous
- bellowing
- swollen vulva
What are the 4 waves of follicular growth?
- Recruitment
- Selection
- Dominance
- Atresia
Estrous cycle length in ewe?
17 days
Signs of estrous in ewe?
- seek out ram
2. vulvar edema
When do doe’s reach puberty?
6-8 months
How long is the estrous cycle in doe?
20 days
How can you ditect estrus in doe?
- swollen vulva
- side to side tail movement
- vag. mucous
Estrous cycle length in sow
21 days
Estrous cycle length in mare
21 days
T/F In mares there is low estrogen during estrus instead of estrogen
T
Estrous cycle length in dog
6 months
What are the 4 phases of the dog estrous cycle?
- proetsrus
- estrus
- diestrus
- anestrus