fibromyalgia Flashcards
true or false, fibromyalgia is a disorder of the PNS
flax, CNS
fibromyalgia is neurosensory disorder of the BLANK
CNS
fibromyalgia isBLANK disorder of the CNS
neurosensory
explain the neurological basis to fibromayliagia
There is greater neuronal activity in pain-processing brain regions (somatosensory cortex), exaggerated pain responses to stimuli (altered processing of nociceptive stimuli), changes in brain morphology and altered levels of pain-related neuropeptides and neurotransmitters (for example, substance P, brain-derived neurotrophic factor, glutamine, and dopamine).
Newest research shows the activation of glial cells that release inflammatory mediators which do what for fibromyalgia
thought to sensitize pain pathways and cause symptoms of fatigue
what can sensitize pain pathways and cause symptoms of fatigue.
activation of glial cells that release inflammatory mediators
fibromyalgia is a dysregulation of what
Dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) axis and the sympathetic nervous system
Dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) axis and the sympathetic nervous system affects the response to what modality
pain
explain affect of negative emotions and fibromyalgia
Negative emotions can lead to neuroendocrine cascade that causes flulike symptoms, depression, fatigue, myalgias, cognitive difficulties and poor sleep
Negative emotions can lead to BLANK that causes flulike symptoms, depression, fatigue, myalgias, cognitive difficulties and poor sleep
neuroendocrine cascade
is the prevalence of fibromyalgia more common in europe or US
europe
are males or females more commonly diagnosed with fibromyalgia
females (9:1)
what ethnicityy has a higher prev of fibromyalgia in US
african american (compared to white women)
what is the age of fibromaylai
between 20-50 y.o. (mostly between 20-40 y.o), it is also observed in pediatric populations, especially adolescents
when are more diagnoses of fibro given
between 20-40
is fibre only affecting 20-40
no , also seen in pediatrics
are there any genetic factors associated with fibromyalgia
t is more likely to develop fibromyalgia if a parent or sibling also has the condition
true or false: t is less likely to develop fibromyalgia if a parent or sibling also has the condition
false, more
what are the common symptoms of fibromyalgia
Pain, that can be in specific areas of the body or diffuse, and can travel depending on the day. Pain also leads to decreased activity which causes even more pain/fatigue/stiffness. Fatigue, Stiffness, Decreased mood/ depression, and Decreased sleep which often leads to decreased cognition (memory/concentration).
is pain only specific in fibromyalgia
no , can be Pain, that can be in specific areas of the body or diffuse, and can travel depending on the day.
what is the diagnosis criteria for fibromyalgia
Widespread Pain persistent for at least 3 months:
- Pain on both sides of the body
- Pain above and below the waist
Pain in 11/18 tender points (based on the 2010 ACR preliminary diagnostic criteria points), which may fluctuate over time The individual does not have another disorder that would otherwise explain their pain.
to be diagnosed with fibromyalgia, you need to have Widespread Pain persistent how long
3 months
how many tender points do you need to have for fibromyalgia
11/18
what are the associated conditions with fibromyalgia
75-90% of individuals have fatigue, nonrestorative sleep, and Eosinophilia-myalgia syndrome. Many individuals with fibromyalgia also have tension headaches, temporomandibular joint (TMJ) disorders, irritable bowel syndrome, anxiety and depression.