Female Reproductive System Flashcards
Menstrual Cycle
- reproductive cycle
- female organs undergo changes
- averages 28 days
- affects all reproductive organs
Female Internal reproductive organs
- gonads=ovaries
- accessory ducts
- uterine tubes
- uterus
- vagina
Ovaries
- paired
- amond shaped
- 3 cm by 1.3 cm by 1 cm
- lie against the bony lateral wall of true pelvis
- in the fork of iliac vessels
- smooth in young girls
- scarred and pitted after puberty from monthly release of ova
- retroperitoneal but surrounded by peritoneal cavity
Mesovarium
- mesentery of ovaries
- horizontal
- holds ovaries in place
- part of broad ligament
Broad ligament of peritoneum
(ovaries)
- large fold of peritoneum
- hangs from uterus and uterine tube like a tent
- contains mesovarium
suspensory ligament of the ovary
- lateral continuation of broad ligament
- attaches the ovary to the lateral pelvic wall
ovarian ligament
- anchors ovary to uterus medially
- distinct fibrous band enclosed within broad ligament
Veins, arteries and nerves of ovary
- ovarian arteries
- branches of abdominal aorta
- ovarian branches of uterine arteries
- arise from internal iliac artery
- veins, nerves and arteries reach ovary through the suspensory ligament and then through mesovarium
- innervated by both divisions of the autonomic nervous system
tunica albuginea
ovary
- fibrous capsule that surrounds ovary
- much thinner than tunica albuginea of testis
- covered by germinal epithelium
- simple cuboidal epithelium
- does not germinate ova
ovarian cortex
- houses the developing gametes (oocytes) while in the ovary
developing gametes in females
oocytes
follicles
- little bags
- saclike multistructure in which oocytes occur
- enlarge substantially as they mature
ovarian medulla
- loose connective tissue
- containes the largest blood vessels, nerves, and lymphatic vessels of the ovary
- enter through hilium
- slit where mesovarium attaches
- enter through hilium
ovarian cycle
- mestrual cycle in relation to ovary
- Phases:
- Follicular phase (first 1/2)
- ovulation
- luteal phase
Follicular phase
(ovarian cycle)
- the start of each ovarian cycle
- 6-12 primordial follicles start to grow
- lasts two weeks
- growth is stimulated by follicle stimulating hormone (FSH)
- from anterior part of pituitart gland
primordial follicles
(ovarian cycle)
- the majority of follicles in the ovarian cortex
- from which all follicle stages arise
- consist of:
- oocyte surrounded by follicular cells
- a layer of flate supportive cells
- oocyte surrounded by follicular cells
primary follicle
(ovarian cycle)
- primordial follicle starts to grow
- flat cells become cuboidal
- oocyte grows larger
granulosa cells
(ovarian cycle)
- follicular cells multiply to form a stratified epithelium around oocyte
- follicular cells are now granulosa cells
zona pellucida
(ovarian cycle)
- the oocyte’s glycoprotein coat
- protective shell that a sperm must penetrate to fertilize
theca folliculi
(ovarian cycle)
- “box around the follicle”
- a layer of connective tissue that condenses around the exterior of the primary follicle
- theca cells are stimulated by luteinizing hormones to secrete androgens
estrogens
- female sex hormones
- granulosa cells under the influence of FSH convert the theca cells’ androgens into estrogen
- stimulates growth and activity of all female sex organs
- signal uterine mucosa to repair itself after each menstrual period
antrum
(ovarian cycle)
- fluid filled cavity
- a clear liquid gathers between granulosa cells and coalesces, forming this cave
secondary (antral) follicle
- once antrum is formed, follicle is now this
corona radiata
- a surrounding coat of granulosa cells
- “radiating crown”
- antrum expands with fluid until it isolates oocycte and this on a stalk at the periphery of the follicle
vesicular (graafian) follicle
(ovarian cycle)
- a full-sized mature follicle
- 2cm in diameter (almost 1 inch)
- ready to be ovulated
ovulation
- midpoint of ovarian cycle
- one oocyte exits from one of the ovaries into peritoneal cavity
- swept into uterine tube
Luteal Phase
(ovarian cycle)
- second half of ovarian cycle
- corpus luteum does not die
- corpus luteum scretes estrogen and progesterone
- signaling mucosa of uterus to prepare for implantation
- if there is no implantation, corpus luteum dies and becomes a scar that is eventually phagocytized
corpus luteum
(ovarian cycle)
- remaining granulosa and theca layers after ovulation
- endocrine gland
- secretes estrogen and progesterone
- signals uterus to prepare for implantation
- dies after two weeks if there is no implantation
corpus albicans
(ovarian cycle)
- “white body”
- scar from corpus luteum
- stays in ovary several months
- shrinks until it is phagocytized by microphages
Oogenesis
- process of ova production
- “egg generation”
- uses meiosis like spermatogenesis
- takes many years to complete
oogonia
- stem cells in the fetal period
- give rise to females lifelong supply of oocytes
- are arrested in an early stage of meiosis I around birth
- turned to primary oocytes
primary oocytes
- oocytes stalled in meiosis since birth
- remain stalled for decades until ovulated by their follicle
- Do not finish meiosis I and begin meiosis II until influence of LH that signals ovulation
secondary oocyte
- oocyte entering meiosis II
- arrested again until sperm penetrates its plasma membrane
Ovum
- egg is called ovum after completion of meiosis II
polar bodies
- three smaller cells produced by oogenesis (apart from large ovum)
- contain primarily DNA
- degenerate quickly without being fertilized or contributing to development of embryo
uterine tubes
- aka oviducts
- aka fallopian tubes
- receive the ovulated oocyte
- site for fertilization
- begins laterally near ovary
- ends medially, emptying into superior part of uterus
- Contains: infundibulum, ampulla, and isthmus
- little or no direct contact with the ovaries
- most common place for ectopic pregnancies
infundibulum
- lateral region of uterine tube
- open funnel
- opens into peritoneal cavity
fimbrae
- surrounds the margin of the infundibulum
- ciliated, fingerlike projections
- drape over ovary
ampulla
- medial to the infundibulum
- forms half the length of the uterine tube
- site where fertilization occurs
isthmus
- narrow passage
- medial third of uterine tube
mesosalpinx
- a short mesentery that covers the uterine tube
- a part of the broad ligament
salpingectomy
- surgical removal of the uterine tube
salpingitis
- inflammation of uterine tube
pelvic inflammatory disease
PID
- widespread infection that originates in vagina and uterus
- spreads to uterine tubes, ovaries, and pelvic peritoneum
- occurs in 10% of women in USA
- caused by chlamydia or gonorrheal infection
- symptoms: tenderness of lower abs, fever, vaginal discharge
- A single episode can cause infertility if not halted
- due to scarring that blocks uterine tubes
- broad-spectrum antibiotics can stop
Uterus
- womb
- lies in pelvic cavity
- anterior to rectum
- posterosuperior to bladder
- hollow, thick walled organ
- shape and size of small inverted pear in women who havent been pregnant
- Function:
- receive, retain, and nourish a fertilized egg throughout pregnancy
Uterus positioning
- normally antiverted: tilted anteriorly at the superior part of vagina
- in older women it is often retroverted.
- inclined posteriorly
body of uterus
- main portion of uterus
fundus of uterus
- rounded region superior to entrance of uterine tubes
isthmus of uterus
- slightly narrow region inferior to the body
cervix of uterus
- beneath isthmus
- narrow neck
- the inferior tip that projects into the vagina
- contains a lot of collagen
- forms a tough, fibrous ring that keeps uterus closed and fetus within it during pregnancy
cervical canal
- part of the central lumen of the uterus
- communicates with the vagina inferiorly
- mucosal lining of canal contains *cervical glands *that fill canal with muscus to block spread of bacteria and sperm entry
external os
of cervical canal
- os=mouth
- communication of cervical canal with vagina inferiorly
internal os
cervical canal
- os=mouth
- communication of cervical canal with the cavity of body (part of lumen of uterus) superiorly
Supports of the uterus
- Main support provided by muscles of the pelvic floor
- urogenital and pelvic diaphragms
- mesomenterium
- lateral cervical (cardinal) ligaments
- round ligaments of uterus
mesomenterium
(uterine support)
- anchors uterus to lateral pelvic walls
- largest division of the broad ligament
lateral cervical (cardinal) ligaments
(uterine support)
- run horizontally from uterine cervix and superior vagina to lateral pelvic walls
- thickenings of the fascia of the pelvis