female reproductive Flashcards

1
Q

estrogen is made in:

A

corpus luteum

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2
Q

estrogen cause proliferation of:

A

stroma, blood vessels, endometrium

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3
Q

function of progesterone:

A

store food in granular cells

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4
Q

commonest causes of vaginal bleeding

A

hormonal disorders, genital neoplasia

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5
Q

types of genital neoplasia?

A

fibroids, endometrial disease, cervical disease

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6
Q

most common benign tumour of myometrium

A

fibroids

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7
Q

___% women have uterine fibroids

A

20

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8
Q

what is DUB?

A

dysfunctional uterine bleeding caused by absence of well-defined organic lesion in the uterus

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9
Q

DUB characterized by:

A

anovulation

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10
Q

endometrial hyerplasia caused by:

A

xs of estrogen (continuous proliferative phase)–>anovulatory cycles around menopause, exogenous estrogen, PCOS

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11
Q

types of endometrial hyperplasia:

A

simple, complex, complex with atypia

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12
Q

two types endometrial carcinoma

A

endometrioid, serous

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13
Q

risk factors of endometrioid?

A

obesity, diabetes, hypertension, infertility, age 55-65

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14
Q

risk factors for serous?

A

> 70 yrs age

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15
Q

serous has a good or bad prognosis?

A

Bad, it’s high grade carcinoma

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16
Q

20% of malignant tumours of female repro tract

A

carcinoma of cervix

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17
Q

early detection of cervical cancer by:

A

PAP smear

18
Q

most common cervical cancer-causing HPV are”

A

type 16 and 18

19
Q

low grade HPV are types:

A

6 and 11

20
Q

cervical cancer arises in ___ zone

A

transformation

21
Q

cervical cancer involves __ cells

A

squamous

22
Q

what is transformation zone?

A

point where squamous epithelium becomes glandular in cervix

23
Q

early symptoms of cervical cancer

A

post-coital bleeding, vaginal discharge

24
Q

pelvic inflammatory disease involves:

A

endometritis, cervicitis, salpingitis, oophoritis

25
Q

is vulvovaginitis usually ascending or descending?

A

ascending (sex)

26
Q

chlamydia presents clinically as:

A

vaginal discharge, ab pain, infertile

27
Q

common infections:

A

herpes (blisters), HPV (warts), infectious vaginitis, chlamydia, gonorrhea, symphilis

28
Q

local symps of gonorrhea

A

urethritis, proctitis, PID, septicemia, arthritis

29
Q

where is milk made?

A

acinar duct

30
Q

____ part of acinar is where disease starts

A

terminal

31
Q

two types of fibrocystic change

A

nonproliferative, proliferative

32
Q

common benign tumour in young femals, 2-5cm

A

fibroadenoma

33
Q

fibroadenoma maybe caused by?

A

exaggerated response of breast tissue to sex hormones (estrogen)

34
Q

incidence of fibroadenoma is :

A

1 in 10 women

35
Q

most common cancer in women

A

breast cancer (1/10 women)

36
Q

risk factors for breast cancer

A

hormonal (E2 exposure, nulliparous women, anti-estrogen drugs), race (Jewish), reproductive history, premalignant fibrocystic changes (papillomatosis)

37
Q

what cause breast cancer?

A

atrophy

38
Q

two types of breast cancer?

A

infiltrating duct, lobular

39
Q

infiltrating duct characterized by a ____ tumour and ___ of nipple

A

firm, gritty; retraction

40
Q

breast cancer detected by:

A

self exam, physician palpation, mammography

41
Q

diagnosis of breast cancer:

A

fine needle aspiration, surgical biopsy