Female Pathology: ovary Flashcards
what is the functional unit of the ovary
follicle
what consists of the ovary
oocyte surrounded by granulosa and theca cells
Where in the ovary does LH hormones act
theca cells: androgen production
where in the ovary does FSH hormone act
stimulates granulosa cells to convert androgen to estradiol
- drives proliferative phase of endometrial cycle
what causes ovulation
estradiol surge induces LH surge
after ovulation, the residual follicle becomes what
corpus luteum
what does corpus luteum secrete
progesterone
when is the most likely time a hemorrhagic corpus luteal cyst occur
pregnancy
degeneration of follicles results in what
follicular cysts
what is polycystic ovarian disease
multiple ovarian follicular cysts due to hormone imbalance
what are LH and FSH levels in polycystic ovarian disease
increase LH
low FSH
LH:FSH greater than 2
what are effects of having increased LH in polycystic ovarian disease
excess androgen production
hirsutism
androgen is converted to what in the adipose tissue in PCOD? what cascade does this make
estrone
- decreases FSH –> cystic degeneration of follicles
high levels or circulating estrone increased risk for what
endometrial carcinoma
what are classic clinical presentation for PCOD
obese young women
infertility
oligomenorrhea
hirsutism
some have insulin resistance, develop type II diabetes
