Fat Degregation It Mitochondria Flashcards
What do we produce from even numbered fatty acids?
We produce acetyl CoA, NADH, and FADH2 through beta-oxidation.
Where does the production of ATP from fatty acids occur?
It occurs in the mitochondria.
What are the four steps of beta-oxidation?
- Oxidation, 2. Hydration, 3. Oxidation, 4. Cleavage.
What is produced in each round of beta-oxidation?
Each round produces 1 FADH2, 1 NADH, and 1 Acetyl CoA.
How much ATP is produced from a 16-carbon fatty acid?
About 100 ATP are produced from a 16-carbon fatty acid.
How many ATP are required for each fatty acid breakdown?
2 ATP are required for each fatty acid breakdown.
Do unsaturated and saturated fatty acids produce the same amount of ATP?
Yes, they produce the same amount of ATP.
What is the function of Enoyl CoA isomerase?
It moves double bonds to C2-3 and changes the double bond from cis to trans.
What happens to odd-chain fatty acids during oxidation?
They produce a 3-carbon molecule, Propionyl-CoA, which is converted to Succinyl-CoA.
How does the ATP yield of a 20-carbon fatty acid compare to a 21-carbon fatty acid?
A 20-carbon fatty acid produces more ATP than a 21-carbon fatty acid.
When are ketone bodies used?
They are used in non-normal states of needing energy, such as pathogenic conditions or starvation.
Where are ketone bodies formed and used?
They are formed in the liver and used by the brain, heart, and kidneys.
What happens to acetone in ketone body metabolism?
Acetone is not a usable ketone body.
What are the two main ketone bodies formed from acetyl CoA?
Acetoacetate and 3-hydroxybutyrate.
What is the role of CoA transferase?
I makes ketone
