Citric acid cycle (TCA) Flashcards
what’s the main point of the TCA cycle
it is looking to extract electrons from Acetyl Coa
what’s the first product of the TCA cycle when Acetyl Coa enters
citrate
where does the TCA cycle occur
mitochondrial matrix
why is TCA cycle a true cycle ? what’s the substrate/product?
the substrate used in the first reaction is produced in the last reaction (oxaloacetate)
can the citric acid cycle only start from glycolysis?
nope, acetyl coa can be fed in from any pathway that produces it
what is produced from every cycle of TCA (1 acetyl coa)
3 NADH
1 FADH2
1 ATP
2 CO2
1st step of TCA cycle?
acetyl coa is fused with oxygen acetate to form citrate
what’s the input fuel for TCA cycle
Acetyl Coa
what enzyme kicks off the TCA cycle
citrate synthase
how many carbons in oxaloacetate
4
how many carbons in acetyl coa
2
how many carbons in citrate
6
what prevents a waste of acetyl coa in the TCA cycle?
ordered sequential mechanism
what is substrate level phosphorylation
forming ATP outside of the electron transport chain
which enzyme is bound to the membrane in the TCA cycle ? what does it produce?
succinate dehydrogenase. FADH2
