Fármacos antihistamínicos Flashcards

1
Q

MoA de los antihistamínicos

A

Agonistas inversos de los receptores H1 (histaminérgicos)

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2
Q

ADME de los antihistamínicos

A

Sustrato de CYPs 3A4, 2D6

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3
Q

EA de los antihistamínicos

A

Inespecíficos: Cefalea. Aticolinérgicos: Boca seca.

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4
Q

Indicaciones de los antihistamínicos

A
  • Rinitis alérgica, urticaria
  • 1ra generación: Medicamentos antigripales, hipnóticos.
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5
Q

Antihistamínicos de 1ra gen

A

Clorfenamina. Difenhidramina. Hidroxizina

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6
Q

Antihistamínicos de 2da gen

A

Loratadina. Cetirizina

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7
Q

Antihistamínicos de 3ra gen

A
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