Family Medicine EOR part 2 Flashcards
Treatment for vasospastic angina
CCBs or nitroglycerina.
Precipitating factors for vasospastic angina?
Early in the morning, cold weather, and emotional stress.
Describe the typical vasospastic angina patient?
Female smoker >50
Cobblestoning of the mucosa on colonoscopy in what condition?
Chron disease
T/F? Ulcerative colitis has “Skip lesions” on colonoscopy.
False - skip lesions are found in Chron disease
What is the most common segment of the GI tract affected by Chron disease?
Terminal ileum
Skin manifestation of Chron disease?
Pyoderma gangrenosum and erythema nodosum
Mainstays of treatment for Chron disease?
5-ASA derivatives, corticosteroids, and immunomodulators.
When is colorectal surgery considered for Chron disease patients?
Fisulizing disease, cachexia, systemic symptoms, intra-abdominal abcesses.
Between Chron’s and ulcerative colitis, which presents with bloody diarrhea and which does not.
UC- bloody
Chron’s - not bloody
What antibody tests are positive in Chron’s?
ASCA
What medication is notorious for causing interstitial lung disease?
Amiodarone
What is the x-ray finding of interstitial lung disease?
Reticular opacities, ground glass opacities, honeycombing, or reticulonodular opacities.
What is the best diagnostic test for interstitial lung disease?
CT
What pear-shaped protozoan has four flagella at its anterior end and can be seen on urine microscopy?
Trichomonas vaginalis.
How long after treatment for chlamydia should retesting occur?
3 weeks
Does strep throat typically cause anterior or posterior cervical chain lymphadenopathy?
Anterior
What are the Centor criteria?
Fever >100.4
Sore throat
Lack of cough
White pharyngotonsillar exudates
How many Centor criteria should be met for patients to undergo strep testing?
3/4
1st line treatment for strep throat?
Oral penicillin or cefuroxime
Treatment for strep throats in patients with penicillin allergy?
Macrolides
Which culture medium is used to isolate Neisseria gonorrhoeae from a throat swab?
Thayer-Martin medium.
What is the definitive treatment for rectocele?
Surgical correction with posterior colporrhaphy.
What is the common name of a pulmonary aneurysm found in tuberculosis that begins in the infected cavity and spreads to the bronchial arteries, causing massive hemoptysis upon rupture?
Rasmussen aneurysm.
What are two causes of a cholesteatoma?
Chronic Eustachian tube dysfunction or tympanic membrane perforation
Symptoms of a cholesteatoma?
Painless malodorous otorrhea and conductive hearing loss
Definitive treatment for cholesteatoma?
Surgical excision with tympanoplasty
Conductive hearing loss associated with cholesteatoma is most commonly due to erosion of which of the ossicles?
The distal portion of the incus.
The vast majority of testicular tumors are?
Germ cell tumors -95%
Risk factors for germ cell tumors?
Cryptorchidism!!, also HIV and hx of Fhx of testicular cancer
What are some abnormal lab findings in testicular cancer?
Elevated HCG, AFP, and LDH.
Diagnosis of testicular cancer is made by?
Inguinal orchiectomy.
Is cryptorchidism more likely to occur on the right or left side?
Right side.
What is the cutoff for HFrEF?
<40% EF
What 3 medication are used in heart failure to improve mortality?
Diuretics, ACEIs and beta blockers
What medication used in HFrEF improves morbidity but not mortality?
Digoxin
Which class does sacubitril-valsartan, a heart failure medication, belong to?
Angiotensin receptor-neprilysin inhibitor (ARNI).
How is orbital cellulitis differentiated from preseptal cellulitis?
Orbital cellulitis has ophthalmoplegia, pain with eye movements, and proptosis.
Initial treatment for orbital cellulitis?
IV vancomycin + ceftriaxone or cefotaxime.
+ metronidazole if rhinosinusitis is present
What anatomical structure is infected in preseptal cellulitis?
Anterior portion of the eyelid.
Which antibiotic is used to treat confirmed pertussis infections?
Macrolides, such as azithromycin.
Back pain accompanied by urinary incontinence or retention should give you concern for?
Cauda equina syndrome
What response with plantar stimulation is a positive Babinski sign in adults characterized by?
Dorsal extension and fanning of the toes.
What labs should be ordered for a patient in whom you suspect hemochromatosis?
Serum iron, TIBC, transferrin saturation (TSAT), and ferritin.
What is indicated in hemochromatosis patients with serum ferritin >1000ng/mL?
an MRI to estimate body iron stores and phlebotomy to prevent progression.
Patients with hemochromatosis have increased risk of infections with what organisms?
Siderophilic organisms
How much alcohol intake per day increases the risk of developing cirrhosis?
Over 30 grams.
Patients testing positive for APC mutation are at high risk of having?
Familial adenomatous polyposis
Patients with familial adenomatous polyposis have a ___% risk of developing CRC.
100%
How often should FAP patients get colonoscopys?
Annually beginning at 12 until a colectomy is performed
What orthopedic test is performed by squeezing the calf muscle and observing for plantar flexion?
Thompson test.
A lateral ankle sprain usually involves what ligament?
Anterior talofibular ligament
What is the mechanism of injury for a lateral ankle sprain?
Inversion injury
What grade sprain is a complete tear of a ligament”?
Grade 3
What rule is used to determine if a patient needs and ankle x ray?
Ottawa ankle rules
What BPH medication reduces the size of the prostate as well as improves symptoms?
Finasteride
What class of medications is finasteride?
5-alpha reductase inhibitor
What drug class is considered first-line pharmacotherapy for dyslipidemia that is recalcitrant to lifestyle modifications?
Statins.
A crescendo-decrescendo murmur hear best at the second right intercostal space describes what murmur?
Aortic stenosis
What is the definitive test to diagnose aortic stenosis?
echocardiogram
What is the definitive treatment for aortic stenosis?
Aortic valve replacement,
What value is considered hypertriglyceridemia?
> 150mg/dL
Triglyceride levels greater than _____ are associated with pancreatitis.
1000
What medication should a patient with a triglyceride level over 500 be prescribed?
A fibrate (fenofibrate or gemfibrozil.)
What is Courvoisier sign?
A nontender palpable enlarged gallbladder that is associated with pancreatic cancer.
What procedure is also known as a pancreaticoduodenectomy and is indicated for treatment of pancreatic cancer?
Whipple procedure.
What x-linked inherited red blood cell enzyme deficiency makes RBCs prone to oxidative injury?
G6PD deficiency
Peripheral blood smear of a G6PD patient reveals?
Heinz bodies and bite cells
What supplement should be initiated in patients with chronic hemolysis?
Folic acid.
What is the most commonly used imaging modality to diagnose a PE?
CT pulmonary angiography.
What is the name of the triad of risk factors for PE?
Virchow triad
What are the components of Virchow triad?
Venous stasis, vascular injury, and hypercoagulability.
What 2 x ray findings, although uncommon, are associated with PE?
Westermark sign and Hampton hump.
Although EKG changes are rare in PE, what EKG finding is highly specific for PE?
S1Q3T3
S wave in lead 1, q wave and t inversion in lead 3.
In patients with high risk for PE but have contraindications to anticoagulation, what treatment is indicated?
Inferior vena cave filter.
What is the treatment for stable patients with a PE?
Anticoag with heparin, direct anticoagulant, or warfarin
What is the treatment for an unstable patient with a PE?
Thrombolytic therapy or ebolectomy.
What is the McGinn-White sign?
An S1Q3T3 pattern seen on ECG in patients with acute right heart strain.
What is the recommended procedural treatment for patients with refractory grade II internal hemorrhoids who are on anticoagulants?
Sclerotherapy because the risk of bleeding is very low.
What anatomic landmark determines whether hemorrhoids are internal or external?
The dentate line.
Name 2 autoimmune diseases that can cause corneal ulcers.
RA and Sjogren syndrome
Tonic-clonic seizures are also known as?
Grand mal seizures
A 24 year old patient presents to the ER after having a grand mal seizure.. He has never had a seizure before. What should you order?
MRI of the head EKG EEG Electrolytes Glucose
Treatment for focal seizures?
Phenytoin, valproic acid, phenobarbital, or lamotrigine
Treatment for absence seizures?
Ethosuximide or valproic acid.
Treatment for tonic clonic seizures?
Carbamazepine, phenobarbital, levetiracetam, or phenytoin
First line treatments for status epilepticus?
IV lorazepam, diazepam, or IM midazolam.
What condition is characterized by a brief period of unilateral paralysis following a seizure?
Todd paralysis.
What is the difference between irritant contact dermatitis and allergic contact dermatitis?
Irritant causes physical, chemical, or mechanical irritation to the skin. Irritant is localized to sites of direct contact.
Allergic contact dermatitis is a type IV hypersensitivity reaction. Allergic may pccur beyond sites of direct contant.
Name some causes of irritant contact dermatitis.
Soaps, detergents, organic solvents
Name some causes of allergic contact dermatitis.
Poison ivy, poison oak, nickel, adhesive tape, topical antimicrobials.
Treatment for allergic contact dermatitis?
Topical corticosteroids for localized involvement and systemic corticosteroids for widespread involvement.
What type of hypersensitivity reaction is a transfusion reaction due to ABO incompatibility classified as?
Type II hypersensitivity reaction.
What is the differential diagnosis for abnormal uterine bleeding?
PALM (structural causes)-COEIN (nonstructural causes) Polyps Adenomyosis Leiomyoma Malignancy Coagulopathy Ovulatory dysfunction Endometriosis Iatrogenic Not yet classified.
When do women with von Willebrand disease typically present with menorrhagia?
Near menarche or at menopause.
Define menorrhagia
Blood loss > 80mL during one cycle.
When should oral bisphosphonates be taken?
In the morning on an empty stomach, and the patient should remain upright for 30 minutes afterward.
What is the first line treatment for osteoporosis?
Bisphosphonates
What is the screening modality for osteoporosis?
DEXA scan
A patient with osteopenia has a T score of?
-1.0 - -2.5
A patient with osteoporosis has a T score of?
What is the second line treatment for osteoporosis for patients who cannot tolerate bisphosphonates?
SERMs such as raloxifene.
What is the gold standard diagnosis for active TB?
Culture of acid-fast bacilli bacteria
List the 4 drugs used to treat active TB.
Rifampin, isoniazid, pyrazinamide, and ethambutol.
Treatment for latent TB?
9 months isoniazid + pyridoxine to combat peripheral neruopathy
OR
4 months rifampin.
Which RIPE antibiotic (rifampin, isoniazid, pyrazinamide, and ethambutol) is associated with higher rates of hepatitis?
Isoniazid.
What is the first-line treatment for primary dysmenorrhea?
Nonsteroidal anti-inflammatory drugs (NSAIDs).
What is the triad of symptoms caused by endometriosis?
Dysmenorrhea, dyschezia,(pain with bowel movements) and dyspareunia (painful intercourse)
Describe the appearance of seborrheic keratosis.
Brown macules and papules with well defined borders with a stuck on appearance and are nodular and rough to the touch.
Are seborrheic keratoses benign of malignant?
Benign.
What is Zollinger-Ellison syndrome?
A gastrin producing neuroendocrine tumor that causes hypersecretion of gastric acid.
What disorder is Zollinger-Ellison syndrome closely associated with?
Multiple endocrine neoplasia type 1.
What is the most effective prescription therapy for smoking cessation?
Varenicline
Bupropion is effective in smoking cessation but is contraindicated in patients with?
Seizures.
When do nicotine withdrawal symptoms peak?
3 days.
What disorder is associated with blue sclerae, short stature, easy bruising, and ligamentous laxity?
Osteogenesis imperfecta.
Which class of medications used for the treatment of osteoporosis has been associated with osteonecrosis of the jaw?
Bisphosphonates.
What is Rovsing sign and what is suggestive of?
Pain in the RLQ when palpating the LLQ.
It is suggestive of appendicitis
What other special tests are suggestive of appedicitis?
Psoas sign
Obturator sign
Where is the Mcburney point?
2/3 of the way from the umbilicus to the anterior superior iliac spine.
The psoas sign if suggestive of _____ position of the appendix whereas the obturator sign is suggestive of the _____ position of the appendix.
Psoas - retrocecal
Obturator - pelvic
Treatment of acute appendicitis?
Surgical appendectomy with a single dose of preoperative antibiotics
What is the preferred imaging study for appendicitis in pregnant women?
MRI of the abdomen and pelvis.
What are the two main cardiac emergencies associated with severe hypertension?
Acute heart failure and acute coronary syndrome.
What two medications should be given to a patient in acute heart failure?
A loop diuretic and a vasodilator such ad sodium nitroprusside or nitroglycerine.
Hypertensive emergency is defined as a blood pressure greater than _____ with evidence of end organ damage.?
180 systolic or 120 diastolic
True or false: hypertensive urgency is defined as a markedly elevated blood pressure without evidence of end-organ damage.
True.
What is the treatment for PTSD?
SSRI and CBT
What is the appropriate treatment for a patient with acute stress disorder?
Psychotherapy.
What is the preferred imaging modality for lumbar radiculopathy?
MRI
What are the most common nerve root radicilopathies?
L5 and S1
S1 radiculopathy pain radiates where?
Posterior thigh, leg, and lateral plantar aspect of foot.
L5 radiculopathy radiates where?
Buttocks wrapping around lateral aspect of thigh and calf to the medial aspect of the dorsum of the foot.