Family Medicine EOR Flashcards
Presenting symptoms of a cervical neck strain?
Pain or stiffness with neck movement.
Causes of cervical neck strains?
Minor injury or physical stressors such as poor posture or sleep habbits.
Name some red flags when evaluating what you think may be a cervical neck strain?
Major trauma, weakness, bowel or bladder dysfunction, cancer symptoms, IVDU, visual changes, anterior neck pain.
Where should you expect tenderness in a cervical neck strain patient?
Paraspinal and trapezius muscles.
T/F? You should get a c spine x-ray in evaluation of cervical neck strains.
False
Treatment for cervical neck strains?
NSAIDs
nonbenzo skeletal muscle relaxers are 2nd line.
How long should a cervical neck strain take to resolve?
Within 6 weeks.
Non-pharmacologic treatments for cervical neck strains?
Home exercise program, heat or cold, modification of posture.
What medications can result in decreased lower esophageal sphincter pressure, causing GERD?
Anticholinergics, antihistamines, CCBs, nitrates, progesterone, and TCAs.
What foods are associated with GERD?
Any large meal, acidic foods, alcohol, fatty foods, spicy foods, chocolate, and peppermint.
Name some atypical GERD symptoms.
Asthma, chronic cough, chronic laryngitis, sore throat, chest pain, and sleep disturbances.
Concerning GERD features?
Dysphagia, odynophagia, weight loss, IDA
Treatment for typical GERD without concerning symptoms?
8 week trial of BID H2RA or QD PPI
Patients who do not respond to PPI or H2RA, or have concerning features should have what procedure?
Endoscopy.
Gold standard for GERD diagnosis?
Esophageal pH testing
Long term PPI use side effects?
Infectious gastroenteritis, IDA, Vit B12 deficiency, hympomagnesemia, pneumonia, hip fractures.
Surgical treatment for GERD if pharmacologic therapy is not an option?
Surgical fundoplication.
First line therapy for H. pylori?
Amoxicillin, clarithromycin, PPI x 14 days
H. pylori is known to cause?
Peptic ulcer disease.
In patients age 30-55, where does peptic ulcer disease most commonly cause ulcers?
Duodenum
In patients age 55-70, where does PUD most commonly cause ulcers?
Gastric
Classic symptom of PUD?
Dull, aching, or gnawing epigastric pain
Pain from PUD can be relieved by?
Eating
How can you test for H. pylori?
Urea breath test or fecal antigen testing
When should a test for cure be done for a patient treated for H. pylori?
4 weeks after completing treatment.
Where is an ulcer located if pain is alleviated by ingesting food?
Duodenum
Where is an ulcer located if it is exacerbated by ingesting food?
Stomach
Is a hordeolum (stye) painful or nonpainful?
Painful
Cause of a hordeolum?
Purulent inflammation of the eyelid often due to bacterial infections (staph aureus)
Upon inspection of a patients eyelid, you see what appears to be an external hordeolum, however it is not painful. You know that it must be a?
Chalazion
Cause of a chalazion?
A blocked oil gland (Meibomian or Zeis gland.)
Diffuse inflammation of the eyelid is called?
Blepharitis
Most common causes of acute pericarditis?
Enteroviruses including coxsackie, adenoviruses, and parvovirus
3 P’s of pericarditis chest pain?
Pleuritic, persistent, postural.
First line treatment for acute pericarditis?
aspirin or NSAIDs + Colchicine to prevent recurrence
EKG findings in pericarditis?
PR elevation in aVR, PR depression, and diffuse ST elevation.
What medication can be added in treatment for acute pericarditis for refractory or severe cases?
Corticosteroids
Acute pericarditis after a myocardial infarction is known as?
Dressler syndrome
First line treatment for Dressler syndrome?
Aspirin and colchicine
Most common side effect of colchicine?
GI upset
What labs should be ordered to rule out treatable causes of dementia?
Vit B12 level
TSH (hypothyroidism)
Two main classes of drugs for treatment of dementia?
Cholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists
Name 3 causes of conjunctivitis.
Bacterial, viral, allergic
Most common pathogens for bacterial conjunctivitis?
Strep pneumo, H. influenzae, M. catarrhalis, staph aureus.
What type of conjunctivitis causes an eye to be “stuck shut” in the morning?
All of them
What is the preferred treatment of bacterial conjunctivitis in contact lens wearers?
Fluoroquinalone drops such as moxifloxacin or ofloxacin drops
What eye drops can be beneficial in treatment of viral or allergic conjunctivitis?
Topical ophthalmic antihistamines or decongestants, such as ketotifen.
A neonate develops severe conjunctivitis 10 days post delivery. What organism do you suspect?
Chlamydia - occurs between 5-14 days of life
A neonate develops severe conjunctivitis 3 days post delivery. What organism do you suspect?
Gonorrhea - occurs betewen 2-5 days of life
A patient presents with deep-seated itching of the ear 1 week after being treated for otitis externa. What do you suspect?
Fungal external otitis. (otomycosis)
What fungi are commonly responsible for fungal external otitis?
Aspergillus and Candida species.
Otoscopic evaluation of a patient reveals “fine coal dust” lining the ear canal. What is the most likely organism?
Aspergillus
Otoscopic evaluation of a patient reveals a soft white pseudo membrane lining the canal. What is the most likely organism?
Candida
Treatment of otomycosis?
Meticulous cleaning and removal of debris, topical antifungals.
What is the preferred agent and duration of therapy for treating otomycosis?
Clotrimazole 1% solution BID x 10-14 days
What class of medications used to treat otitis externa should be avoided in the presence of tympanic membrane perforation?
Aminoglycosides (tobramycin, gentamycin)
Salmonella outbreaks are most commonly associated with?
Poultry and eggs
Definitive diagnosis of salmonellosis is made by?
Stool culture
Most important component of therapy for salmonellosis?
Replacement of fluids and electrolytes
Which virus is associated with outbreaks of gastroenteritis on cruise ships?
Norovirus
Differentiating factors between stable and unstable angina?
Stable - predictably triggered, relieved by rest, less than 30 minute duration
Unstable - acute onset not relieved by rest, lasts longer than 30 minutes, and not relieved by nitroglycerin.
When is a coronary artery bypass graft indicated in coronary artery disease patients?
Left main coronary artery involvement >50% stenosis, >70% stenosis 3 vessel disease, or decreased left ventricular ejection fraction.
When is percutaneous transluminal coronary angioplasty indicated for CAD patients?
1 or 2 vessel disease without left main coronary artery involvement
What is the gold standard diagnostic test for coronary artery disease?
Coronary angiography
What is the cause of syncope?
Inadequate cerbreal blowflow
Four main causes of syncope?
Reflex syncope, orthostatic syncope, cardiac dysrhythmias, and structural cardiopulmonary disease.
Name some symptoms that accompany reflex syncope.
Lightheadedness, warm or cold, sweating, palpitations, nausea, decreased vision or hearing, pallor.
Workup for syncopal episode should include?
H and P, neuro exam, cardiopulmonary exam, EKG
Name some cardiac dysrhythmias that may be seen on EKG in patients with syncope.
Brugada syndrome, short QT syndrome, long QT syndrome, preexcitation, and heart block.
On a stool ova and parasite test, flagellated trophozoites and cysts are reported. What do you suspect the infection to be?
Giardia lamblia
Risk factors for giardia infections?
Wilderness activities, impaired immunity, MSM.
Incubation period of giardia?
1-3 weeks
First line treatment for Giardiasis?
Metronidazole 250mg TID x 5-7 days tinadazole 2g PO single dose.
What patient education can you give on water purification in order to avoid giardia?
Chlorination of water does NOT inactivate cysts. You must filter with a pore size less than 1 mcm or bring water to a boil.
A patient presents 7 days after ingestion of river water while camping. Stool ova and parasite test reveals banana shaped motile sporophytes. What organism do you suspect?
Cryptosporidium parvum
What is the most common medication for malaria to be resistant to?
Chloroquine
Most common patient population to have fibromyalgia?
Women 20-50 years old.
Fibromyalgia is commonly associated with what conditions?
RA, hypothyroidism, anxiety, depression.
What labs are abnormal in fibromyalgia?
None
Nonpharmacologic treatment for fibromyalgia?
CBT, patient education, sleep hygiene, low impact aerobic exercise.
Pharmacologic treatment for fibromyalgia?
TCAs, SSRIs, SNRIs, cyclobenzaprine, pregabalin, gabapentin.
What are the 3 FDA-approved medications for treatment of fibromylgia?
Duloxetine (SNRI), Pregabalin, and milnacipran.
Most common cause of small bowel obstruction?
Adhesions from prior abdominal surgeries.
How is diagnosis of small bowel obstruction made?
Abdominal x rays prone and standing.
CT abd also helps determine the severity.
Do you suspect a small bowel obstruction patient to be acidotic or alkalotic?
Could be either, acidotic if there is ischemic bowel or dehydration.
Alkalotic if patient had hyperemesis.
First steps in treatment of small bowel obstruction?
Nasogastric tube
Withdrawal of oral intake
What x-ray finding for a small bowel occlusion requires immediate surgery?
Free air in the abdomen indicating a bowel perforation
What is the most common cause of a large bowel obstruction?
Neoplasm
What do bowels sound like during small bowel obstruction?
High pitched bowel sounds
What two specific x-ray terms indicate small bowel obstruction?
Stack of coins or string of pearls sign
Most common cause of PID?
STIs (gonorrhea and chlamydia are most common)
What exam finding strongly suggests PID?
Cervical motion tenderness
chandelier sign
What is the most worrisome complication of PID?
Perihepatitis (Fitz-Hugh Curtis syndrome)
First line treatment for PID?
1 time IM ceftriaxone followed by 14 day course of oral doxycycline
Name some physical exam findings for allergic rhinitis.
Pale bogy turbinates, allergic shiners, allergic salute.
Treatment for allergic rhinitis?
Intranasal corticosteroid, second generation antihistamines
Vasomotor rhinitis, a common cause of clear rhinorrhea in older patients, is associated with an increased sensitivity of which nerve?
The vidian nerve.
Lab findings in allergic rhinitis?
Elevated serum IgE
What is Samters triad?
Nasal polyps, asthma, and aspirin sensitivity.
Describe the typical patient with immune thrombocytopenia (idiopathic thombocytogenic purpura).
2-5 year old with history of a recent viral infection.
Lab findings in ITP patient?
Platelets <100k (but not uncommon to see below <30k)
Normal hemoglobin, hematocrit, and WBC count.
Treatment for severe ITP includes?
Platelets, glucocorticoids, IVIG
How long does resolution of ITP typically take?
3-6 months
When can ITP patients be managed outpatient?
If they do not need rapid elevation in platelets, and if bleeding is limited to mild cutaneous bleeding.
Name a common neurologic finding associated with vitamin B12 deficiency anemia.
Gait ataxia
What peripheral blood smear finding is common in Vit B12 deficiency anemia?
Hypersegmented neutrophils.
What labs can help differentiate between a Vit B12 deficiency and folate deficiency?
Methylmalonic acid and homocysteine.
Elevated indicates B12 deficiency, normal indicated folate deficiency.
What is an appropriate regimen to correct a B12 deficiency?
1,000 mcg injection of B12 once a week until corrected, then once a month
What skin finding can be noted in severe iron deficiency anemia?
Chlorosis (pale green discoloration)
What nail finding is expected in iron deficiency anemia?
Koilonychia (spoon nails)
What is a physical exam finding that can help you differentiate between B12 and folate deficiency anemia?
Folate deficiency can present with oral ulcers.
B12 can present with neuropathy.
Name some causes of B12 deficiency.
Veganism, metformin, conditions affecting nutrient absorption (Chron’s)
When a patient presents with a fib, it is important to rule out reversible causes such as ____ and _____.
Thyroid disorders and diabetes mellitus
List the components of CHA2DS2-VASc
CHF HTN Age (64-74=1. >75=2_ DM Stroke TIA or VTE
Which of the following oral antifungals is no longer recommended as first-line oral treatment due to the risk of drug-induced hepatitis?
Ketoconazole.
What organism is the most common cause of tinea versicolor?
Malassezia species
Treatment for tinea versicolor?
Selenium sulfide
First line treatment for hypertension in black patients?
Thiazide like diuretic or long-acting dihydropyridine CCB
First line treatment for hypertension in young patients?
ACEIs, ARBs, (Beta blokcers if they have other conditions that would benefit)
First line treatment for hypertension in old patients?
Thiazide-like diuretic or long-acting CCB
What type of hypertension can be treated with lifestyle modifications?
Primary hypertension (resulting from multiple genetic and environmental factors including age, obesity, high-sodium diet, and physical inactivity)
Name 3 common manifestations of SLE.
Malar rash sparing nasolabial folds
Raynaud phenomenon
Photosensitivity
(these were the bolded ones in rosh, I know theres a lot)
What lab tests have high specificity for SLE?
Anti-double-stranded DNA
anti-Smith antibodies
Can patients with SLE receive vaccines?
Only before starting immunosuppressive therapies.
An SLE patient comes into primary care for pre-conception counseling. What do you make sure to advise her of?
She should avoid pregnancy for 6 months after active diesase.
Which antibody is associated with drug-induced lupus erythematosus?
Antihistone antibody.
At what location is the murmur for aortic regurgitation heard?
Left upper sternal border
Symptoms of aortic regurgitation?
Exertional dyspnea, hyperdynamic apical pulse, wide pulse pressure.
What does the murmur of aortic regurgitation sound like?
Acute - low pitched, early diastolic murmur
Chronic - high-pitched, holodiastolic murmur
What should a aortic regurgitation murmur do when the patient preforms a Valsalva maneuver?
Decrease in intensity
The initial imaging test of choice for aortic regurgitation is?
Transthoracic echocardiogram
What is the definitive management for aortic regurgitation?
Surgical repair or replacement
What is the most common cause of aortic regurgitation?
Endocarditis
What medication should a patient be started on after a aortic valve replacement?
warfarin
What is the goal INR for a valve replacement patient?
2.5-3.5
What is an Austin Flint murmur?
A late diastolic murmur best heard at the apex. The sound heard is due to retrograde blood flow competing with antegrade flow from the left atrium.
What is Duroziez sign?
What is it a sign of?
A systolic and/or diastolic thrill or murmur heard over the femoral arteries.
It is a sign of aortic regurgitation
What type of airway disease is asthma?
Obstructive
What do you expect FEV1 and FVC to be in asthma?
Increased FEV1 and decrease FVC.
What is the FEV1/FVC ratio expected in obstructive airway conditions?
<0.70
Treatment for intermitent asthma?
SABA PRN
Treatment for mild persistent asthma?
SABA + low dose ICS
Treatment for moderate persistent asthma?
LABA + low dose ICS
Treatment for severe persistent asthma?
LABA + medium dose ICS
Which class of medication is montelukast?
Leukotriene inhibitor.
Name some medications that can cause erosive esophagitis?
NSAIDs Bisphosphonates Potassium Chloride Quinidine Vit C
Symptoms of erosive esophagitis?
Dysphagia, odynophagia, retrosternal chest pain
In a patient with esophagitis, what red flags would make you want to perform an upper endoscopy?
Hematemesis, abd pain, weight loss, persistent symptoms after discontinuation of medication
What measures can be taken to prevent esophagitis caused by medications?
Standing upright for 30 minutes after taking medication, eating meal after taking the medication, taking the medication with at least 8oz water.
What is the first-line treatment for benign esophageal strictures?
Esophageal dilation.
What is the diagnostic criteria for chronic insomnia?
Difficulty falling or staying asleep at least 3 times a week for > 3 months
What is the preferred first-line treatment for insomnia?
CBT
What are some pharmacologic treatments for insomnia?
Benzos
Non-benzo receptor agonists (Z drugs)
What are the two most common relaxation-based strategies used for insomnia disorder?
Progressive muscle relaxation and diaphragmatic breathing.
What lab values are abnormal in irritable bowel syndrome?
none
What type of diet can be beneficial for IBS?
FODMAP
Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols
First line treatment for abdominal pain in IBS?
Antispasmodics such as dicyclomine of hyoscyamine.
Which COPD therapy has been shown to improve survival?
Long-term continuous oxygen therapy.
What are the two most common risk factors for CAD?
HTN and DM
What two diagnostics are important in the evaluation of CAD?
Cardiac enzymes and EKG
A lesion in which vessel is indicated by ST elevations in leads V1, V2, V3, and V4?
Left anterior descending (LAD).
What is the cause of diabetes mellitus type 1?
Pancreatic islet B cell destruction which is primarily autoimmune.
Describe the typical age of a patient at time of diagnosis of DM 1
Child to young adult
What is the cause of diabetes mellitus type 2?
Pancreatic beta cell dysfunction combined with insulin resistance.
When is DM II usually diagnosed?
Predominantly occurs in adults.
What is the most important environmental factor causing insulin resistance?
Obesity.
Symptoms of DM I?
Polyuria, polydipsia, weight loss with normal appetite.
Patients may have muscles wasting and weakness, paresthesias, and peripheral neuropathy.
Symptoms of DM II?
Typically asymptomatic because progression is slow.
Name 1 skin finding associated with insulin resistance.
Acanthosis nigricans
What is the criteria for diagnosing diabetes?
Random plasma glucose >200 in a symptomatic pt
Fasting plasma glucose >126 on two sperate occasions.
Glucose level >200 2 hours post oral glucose tolerance test.
H1C >6.5%
What type of obesity is associated with insulin insensitivity?
Visceral obesity due to the accumulation of fat in the omental and mesenteric regions.
An acute gout attack should be treated with?
NSAID such as indomethacin
Name some medications that increase risk for hyperuricemia.
Diuretics, thiazides, aspirin, cyclosporine, niacin.
Name 2 dietary risk factors for gout.
Excessive alcohol ingestion (particularly beer) and a high-purine diet.
What joint is most commonly affected by gout?
The MTP of the great toe
The definitive diagnosis of gout is made by?
Joint fluid aspirate showing Negatively birefringent needle shaped sodium urate crystals.
What x ray finding is expected in chronic gout?
Rat bite erosions
What medications reduce the risk of recurrence of gout and what is their mechanism?
Allopurinol - decreases production of uric acid
Colchicine and probenecid increase urinary excretion of uric acid.
What diagnosis are positively birefringent, rhomboid-shaped crystals in synovial fluid consistent with?
Pseudogout, also known as calcium pyrophosphate deposition.
What are the most common side effects of metformin?
Nausea, vomiting, diarrhea, flatulence, abd cramping.
What is the mechanism of action of saxagliptin?
Saxagliptin is a dipeptidyl peptidase-4 inhibitor that prolongs incretin levels and decreases glucagon secretion.
Describe the genetic mutation known as the Philadelphia chomosome.
Reciprocal translocation on the long arms of chromosomes 9 and 22
What disorder is caused by the Philadelphia chromosome?
Chronic myelogenous leukemia
What is the age range that patients begin to develop symptoms of CML?
40-60
What are the symptoms of CML?
splenomegaly, fever, night sweats, and weight loss
Lab findings in CML?
Increased WBC count
Peripheral blood smear shows greater percentage of blast cells.
Treatment for CML?
Allogenic hematopoietic cell transplantation
What is the most common childhood leukemia?
Acute lymphocytic leukemia
Auer rods are seen in what type of leukemia?
Acute myelogenous leukemia
What is the most common adult leukemia?
Chronic lymphocytic leukemia
Smudge cells are seen in what type of leukemia?
Chronic lymphocytic leukemia
What disease causes non-caseating granulomas forming throughout the body?
Sarcoidosis
What two organs are most commonly affected by sarcoidosis?
Skin and lungs
Describe skin findings of sarcoidosis.
Erythematous, painful, warm patches and nodules that appear on the shins, arms, and buttocks.
What is the name of the rash caused by sarcoidosis?
Erythema nodosum
What are the chest x ray findings on a typical sarcoidosis patient?
Bilateral hilar adenopathy
Diagnostic test of choice for sarcoidosis?
Transbronchial lung bopsy
On what test are lambda and panda signs seen?
Gallium scintigraphy
What abnormal bloodwork is present in sarcoidosis?
Hypercalcemia and elevated serum ACE, ESR and CRP elevated.
Treatment for sarcoidosis?
steroids
When does symptom onset for parkinsons typically occur?
45-65 years
Name the common clinical manifestations of parkinsons.
Resting or pill-rolling tremor, cogwheel or lead pipe rigidity, bradykinesia, postural instability, masked facies.
What is dysdiadochokinesia?
Loss of ability to preform rapid alternating movements.