Cardiac Cases Flashcards
INR foal for an atrial fib patient?
2-3
INR goal for a patient with valve replacement?
2.5-3.5
T/F. Coumadin failure is defined as a VTE while a patient is taking coumadin.
False - the patient MUST be on coumadin at a THERAPUTIC LEVEL
A shit load of antibiotics have interactions with coumadin. Name 2 antibiotics that have MINIMAL interactions with coumadin.
Cephalexin and clindamycin
What is the reversal agent for coumadin?
Vitamin K
What foods are high in vitamin K?
Basically green vegetables.
Banana, chickpeas, fuit, oil, peppers, and tomatoes also have some vitamin K
What advantages does warfarin have over DOAC’s?
Cheap
Best for ESRD
Must use in valvular AF
What are the drawbacks to warfarin?
Many food and drug interactions
Narrow therapeutic window
What are the advantages of DOAC’s?
Few interactions
Less ICH and fatal bleeding events
No monitoring needed
Bridging not needed due to rapid onsent/offset
What are the drawbacks to DOAC’s?
Costly
Costly/unavailable reversal agents
Higher rate of GI bleeding
Which anticoagulants require renal dosing?
All of them
Does Coumadin have a reversal agent? If so, what is it?
Yes, Vitamin K
Does Dabigatran (Pradaxa) have a reversal agent? If so, what is it?
Yes, Praxbind
Does Rivaroxaban have a reversal agent? If so, what is it?
Yes - AndexXa
Does Apixiban (Eliquis) have a reversal agent? If so, what is it?
Yes - AndexXa