Diabetes Meds

Question 1

What class of diabetes medications works by inhibiting postprandial glucagon release, and slowing gastric emptying?

Answer 1

GLP-1 Agonists

Question 2

What class of diabetes medications works by enhancing insulin sensitivity in muscle and fat by increasing glucose transporter expression (PPAR-Gamma activator)?

Answer 2

Thiazolidinedione’s

Question 3

What class of diabetes medications works by inhibiting hepatic glycogenolysis, inhibiting hepatic gluconeogenesis, and enhancing insulin sensitivity in muscle and fat?

Answer 3

Biguanides

Question 4

What class of diabetes medications works by inhibiting degradation of endogenous incretins which increases insulin secretion, and decreasing glucagon secretions?

Answer 4

DPP-4 inhibitors

Question 5

What class of diabetes medications works by stimulating pancreatic insulin secretion?

Answer 5

Sulfonylureas and Meglitinides

Question 6

What class of diabetes medications works by decreasing glucose absorption and increasing urinary glucose excretion?

Answer 6

SGLT2 inhibitors

Question 7

What medications are in the Biguanide class of diabetes medications?

Answer 7

Metformin

Question 8

What medications are in the DPP-4 inhibitor class of diabetes medications?

Answer 8

Linagliptin (Tradjenta)
Saxagliptin (Onglyza)
Sitagliptin (Januvia)

Question 9

What medications are in the GLP-1 agonist class of diabetes medications?

Answer 9

Exenatide (Byetta)
Exenatide ER (Bydureon)
Liraglutide (Victoza)
Tanzeum 
Trulicity

Question 10

What medications are in the sulfonylurea class of diabetes medications?

Answer 10

Glyburide (Micronase, Diabeta)
Glipizide (Glucotrol)
Glimepiride (Amaryl)

Question 11

What medications are in the thiazolidinedione class of diabetes medications?

Answer 11

Rosiglitazone (avandia)

Piogliatzone (Actos)

Question 12

What medications are in the meglitinides class of diabetes medications?

Answer 12

Repraglinide (Prandin)

Nateglinide (Starlix)

Question 13

What medications are in the SGLT2 inhibitor class of diabetes medications?

Answer 13

Canagliflozin
Dapagliflozin
Empagliflozin

Question 14

List the top 3 classes that lower A1C the most.

Answer 14

Biguanides - lower A1C 1-2%
Sulfonylureas - lower A1C 1-2%
GLP-1 agonists - lower A1C 0.5-1.5%

Question 15

What class of diabetes medications works by blocking alpha-glucosidase in the brush borders of the small intestine to slow breakdown of carbohydrates to glucose?

Answer 15

alpha-glucosidase inhibitors

Question 16

What medications are in the alpha-glucosidase class of diabetes medications?

Answer 16

Acarbose (Precose)

Miglitol (Glyset)

Question 17

List the types of insulin from shortest to longest acting.

Answer 17

Short: Insulin lispro, aspart (Novolog), and glulisine (apidra)
Regular insulin
NPH insulin
Detemir
Glargine