Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step2 > FA Haematology > Flashcards

FA Haematology Flashcards

1
Q

How do platelets bind to vwf

A

GP1b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

PT measures

A

Extrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PTT measures

A

Intrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Warfarin monitor

A

PT (affects both but 7 has shortest half-life)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What synthesizes vit K?

A

Enteric bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How do clotting factors get activated

A

Gamma carboxylation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DOAC reversal

A

Andexanet alfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

tPA can cause

A

Angiooedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Heparin reversal

A

Protamine sulphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dabgatrin reversal

A

Idarucizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Inhibits epoxide reductase

A

Warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Doac vs warfarin metabolism

A

Renal, hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

INR monitoring

A

> 10 - stop and give vit k
4.5 - 10 - hold and can give vit k
<4.5 - hold next dose and then go to maintenance (adjust)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What blood replacement product has high concentration of fibrinogen, VIII, vWF

A

Cryoprecipitate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Who gets haemophilia C?

A

Ashkenazi Jewish

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Best source of factor 8 and fibrinogen?

A

Cryo
FFP also has

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Heyde syndrome

A

Aortic stenosis, GI bleeding, acquired vWD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Diagnosis of vWD

A

Reduced agglitination on Ristocetin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most common inherited bleeding disorder

A

vWD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Treat vWD

A

Desmopressin, antifibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Provoked DVT treatmentt

A

3-6 months
Lifelong if more

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

DVT but anticoagulant is contraindicated

A

IVC filters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Protein C deficiency causes

A

Skin necrosis with warfarin administration

24
Q

APS effects

A

Coagulation defects
Livedo reticularis
Obstetric comp
Thrombocytopenia
SLE

25
Q

Does DIC have haemorrhage or thrombosis?

A

Both!

26
Q

Antibodies in APS

A

Lupus anticoagulant
Beta 2 glycoprotein
Cardiolipin

27
Q

TTP treatment

A

Plasma exchange, steroids

28
Q

Fibrinogen TTP, HUS, DIC

A

Only affected in DIC (low)

29
Q

What is wrong on labs in VWD

A

only increased bleeding (can affect PTT because of factor 8)

30
Q

What is ITP?

A

IgG against membrane protein G2b/3a

31
Q

Treat ITP

A

<30,000 or bleeding = steroids, IVIg

32
Q

Haemolytic vs non-haemolytic anaemia

A

Reticulocyte (increased vs decreased)

33
Q

Microcytic anaemias can be split into

A

Defect harm (iron def. lead poison, sideroblastic, acd) and global (thalassemia)

34
Q

Non-megaloblastic macrocytic

A

Liver
Alcohol

35
Q

Most accurate IDA test?

A

Prussian blue bone barrow stain

36
Q

Does thalassemia anaemia respond to iron ?

A

No

37
Q

Lead lines aka

A

Burton lines

38
Q

What TB drug can cause sideroblastic anaemia?

A

Isonizab

39
Q

Microcytic anaemia where serum iron is elevated

A

Sideroblastic

40
Q

HbH

A

3

41
Q

Hb Barts

A

4

42
Q

Warm AIHA

A

IgG
SLE, CLL, penicillin, rifampicin, phenytoin, methyldopa

43
Q

Cold AIHA

A

IgM
Myocoplasma
EBV
Waldenstrom

44
Q

B12 can be caused by

A

Diphyllobothrium lactum

45
Q

Phenytoin use causeswhat deficiency

A

Folate deficiency

46
Q

Felty

A

Neutropenia
Splenomegaly
RA

47
Q

ABPA diagnosis

A

IGE against A fumingatus

48
Q

Leukaemia most accurate test

A

Bone marrow biopsy with flow cytometry

49
Q

Non-hodgkin vs hodgkin cells

A

Mainly B
Reed Sternberg

50
Q

Alcohol induced lymph node pain

A

Hodgkins lymphoma

51
Q

Dutcher bodies

A

Wallenstrom

52
Q

AL amyloid

A

MM Waldenstrom

53
Q

AA amyloid

A

RA, inflammatory

54
Q

Transplant between twins

A

Syngeneic

55
Q

Allogeneic

A

Donor to genetically different patient

56
Q

GVHD affects

A

Skin, GI, liver, lung

57
Q
A

Step2 (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions