Excitable Cells Flashcards

1
Q

what is action potential?

A

a brief flip flop in polarity across the membrane

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2
Q

why is action potential important?

A

it is how nerves and muscles contract

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3
Q

how does sodium ions enter the cell?

A

through facilitated diffusion

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4
Q

why does the cell loose positive charge?

A

potassium moves out the cell, therefore the cell looses the positive charge

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5
Q

what happens during the depolarizing stage

A

there is a change in sodium; positive charge is entering the cell

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6
Q

what happens during the repolarizing stage

A

there is a change in potassium; moves out the cell

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7
Q

what is the threshold

A

-55

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8
Q

what is the resting membrane potential

A

-70

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9
Q

what is the peak

A

+30

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10
Q

is action potential graded or not graded

A

not graded; meaning all the responses are identical once the threshold is met

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11
Q

what channels open during depolarization

A

voltage-gated ion channels open so the axon keeps gaining positive charge

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12
Q

when does the refractory period take place

A

beginning of hyperpolarization

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13
Q

do concentration gradients change during an action potential

A

the overall concentration gradients for Na+ and K+ do not change during an action potential

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14
Q

is action potential required

A

nerves have to have action potential in order to function properly

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15
Q

what does absolute refractory mean

A

the cell cant respond at all

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16
Q

what does relative refractory mean

A

the cell needs a bigger stimulus then usual to reach threshold

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17
Q

are leaky potassium channels always open ?

A

yes

18
Q

what kind of stimulus is needed during the refractory period

A

a larger stimulus because its farther from threshold

19
Q

what is the purpose of an inactivation gate

A

prevents the cell from being stimulated again until you are done with action potential

20
Q

when do the inactivation gates slide into place

A

at the peak

21
Q

what does propagate mean

A

to make more

22
Q

where do action potentials take place

A

in the axon

23
Q

what is the cell membrane mostly made of

A

phospholipids

24
Q

what is the axon covered in

A

mylein

25
Q

why is mylein covering the axon important

A

it increases speed, because it insulates the axon

26
Q

why kind of charge flows under the myelin

A

positive charge

27
Q

what occurs when there is a small space where the mylein isnt covering the axon

A

the sodium channels are open and the membrane reaches peak

28
Q

what is velocity

A

how fast the axon conducts information

29
Q

whats the difference between a myelinated axon and an unmyelinated axon?

A

a myelinated axon carries information faster with less friction, while covering more area (its thicker)

30
Q

what kind of diffusion is ion movement

A

passive diffusion

31
Q

what happens once threshold is met

A

sodium enters

32
Q

which channels open first

A

sodium channels, then potassium

33
Q

what is passive diffusion

A

type of membrane transport that does not require energy to move substances across cell membranes

34
Q

which ion channels happen on the synaptic knob

A

voltage-gated calcium channels

35
Q

what does blood calcium reflect

A

extracellular calcium

36
Q

what is the importance of calcium

A

calcium helps the vesicles migrate to the synaptic cleft; calcium also helps to trigger the neurotransmitters to be released

37
Q

what does exocytosis mean

A

to move something out of the cell

38
Q

what are the steps of exocytosis

A

the cell manufacturers the neurotransmitters, the neurotransmitters are packaged within the vesicle, the vesicle fuses with the cell membrane and becomes a part of it, the calcium stimulates the vesicles to move to the synaptic cleft and then the neurotransmitter is released from the cell

39
Q

what happens to the neurotransmitter once exocytosis process is over

A

once the neurotransmitter binds to the voltage channel, some of the neurotransmitters are removed by an enzyme out of the synaptic cleft while some neurotransmitters are recycled so they will go back by a process called endocytosis

40
Q

where is electrical synapses found

A

cardiac muscle and smooth muscle

41
Q

why are gap junctions important in cardiac muscle and smooth muscle

A

because they allow for an exchange of cytoplasmic products