exam clinical trail information Flashcards
clinical trials are
research studies involving people that try to answer a scientific question, to find ways to prevent, diagnose or treat disease.
why clinical trials
Effectiveness of treatment, safety of a new drug or device, defining dose administration, testing drug formulation, exploring combination therapies, evaluating effect of therapies on quality of life
Types of clinical trials
Treatment
Prevention
Screening
Supportive and palliative care
treatment trails participants
Use people already with cancer and new treatments
why treatment trials
ew treatments
Drugs, vaccines, approaches to surgery or rt, combinations of treatments, many newer treatment trials require people to have their tumours tested for generic changes first to see if treatment targeting specific changes might work better for them than standard treatment
treatment trails want to find out
Safe dose, how should the treatment be given, does it help people live longer, side effects,
participants in prevention trials
Cancer prevention trials involve healthy people. They will either be people with a high risk of developing cancer or have had cancer in the past and have a high chance of developing a new one
prevention trials are to
Looking at cancer risk and ways to reduce the risk
Researchers want to know in prevention trials
How safe it is for a person to take this agent or do this activity
Does the new approach prevent cancer
Two types of prevention trails
Actions studies - focus on finding out wether actions people take can prevent cancer, ie exercise, fruits and vegetables
Agent studies - focus on fiding out wether taking medicines, vitamines, minerals or dietary supplements may lower the risk of a certain type of cancer
Goal of screening trials
Test new ways to find disease early, when its easier to be treated
For screening trials they want to know
Does finding disease earlier, before people have any symptoms, save lives
Is one screening better than another
Do the large number of people who receive screening tests undergo unnecessary follow up tests and procedures
why do they need effective screening tests
Reduce the number of deaths due to the cancer screening
Quality of life/supportive care/palliative care trials look at
These trials look at ways to improve the quality of life of cancer patients, especially those who have side effects from cancer and its treatments
quality of life/supportive care/palliative care wants to find
New ways to help people cope with Pain Nutrition problems Infection Nausea and vomiting Sleep disorders Depression Other health problems
