Exam 3 - Lecture 20: Enterobacteriaceae & Pseudomonas Flashcards

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1
Q

2

What type of bacteria are enterobacteriaceae and pseudomonas?

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2
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2

Are enterobacteriaceae and pseudomonas spore formers or not?

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3
Q

3

Enterobacteriaceae and pseudomonas are the _____ and most ____ group of bacteria. They cause a ______.

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4
Q

3

Enterobacteriaceae and pseudomonas account for ___ of all bacteremia.

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5
Q

3

Enterobacteriaceae and pseudomonas account for _____% of all UTIs

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6
Q

3

Enterobacteriaceae and pseudomonas cause ____ infections.

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7
Q

4

Enterobacteriaceae are found in the _________.

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8
Q

4

Enterobacteriaceae are ____ and ______ pathogens, as well as important _____ pathogens.

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9
Q

4

How many species are there of enterobacteriaceae?

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10
Q

5

What are 4 common medically important enteroobacteriaceae?

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11
Q

6

What are 5 sites of infection for enterobacteriaceae?

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12
Q

7

How do lactose fermenters apoear on differential/selective media as opposed to lactose non-fermenters?

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13
Q

8

What are 5 components of the antigenic species of enterobacteriaceae?

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14
Q

8

What is K antigen?

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15
Q

8

What is H antigen?

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16
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8

What is O antigen?

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17
Q

8

What type of molecule is pili?

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18
Q

8

What type of activity does Lipid A have?

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19
Q

9

What are two mechanisms of pathogenesisi for enterobacteriaceae?

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20
Q

9

Enterotoxins are involved in _____ and ____.

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21
Q

9

Hemolysins have what two functions?

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22
Q

9

Enterobacteriaceae invade by penetrating the ______ and are associated with ______ infections.

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23
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10

Endotoxins are found in ____ bacteria.

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24
Q

10

What is the toxic moiety for endotoxins?

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25
Q

10

Endotoxins are involved in what 5 things?

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26
Q

11

What is the lab diagnosis for E. coli?

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27
Q

11

E. coli has _____ to antibiotics.

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28
Q

12

What are 5 mechanisms of pathogenesis?

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29
Q

12

What are siderophores?

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30
Q

12
Slime is _____ and offers a protective coat.

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31
Q

13

What does ExPEC stand for?

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32
Q

13

Extraintestinal pathogenic E. coli occupy a niche in the _________ of humans.

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33
Q

13

Extraintestinal pathogenic E. coli causes both _____ and _____ infections.

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34
Q

13

What are 4 infections caused by ExPEC?

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35
Q

13

ExPEC has acquired many ________ genes.

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36
Q

13

Uropathogenic E. coli cause most ______. Specific ____ are usually involved.

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37
Q

13

ExPEC causes ____ in the bladder and _____ in the kidney.

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38
Q

14

UTIs are ____% community and most _____.

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39
Q

14

What are 5 clinical manifestations of E. coli?

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40
Q

14

What are 3 virulence factors involved with E. coli?

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41
Q

15

Neonatal meninigitis is second only to ______.

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42
Q

15

What is the source of neonatal meningitis?

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43
Q

15

What is the specific serotype involved in neonatal meningitis? What percent of strains have this serotype?

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44
Q

16

Septicemina is the leading cause of ______.

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45
Q

17

What are the 4 diarrheagenic E. coli?

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46
Q

18

What is the most important diarrheagenic E. coli?

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47
Q

18

Enterohemorrhabic E. coli is seen in the _____ and is absent in the _____.

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48
Q

18

There are an estimated _____ cases in the USA annually for Enterohemorrhagic E. coli.

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49
Q

18

Enterohemorrhagic E. coli in the large intestine causes ____ then _____, and _____.

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50
Q

18

What is the source of Enterohemorrhagic E. coli?

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51
Q

18

What toxins are carried by Enterohemorrhagic E. coli?

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52
Q

19

What percent of Enterohemorrhagic E. coli cause hemolytic uremic syndrome, low red blood cell count, and kidney failure due to damage to the very small blood vessels of the kidneys?

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53
Q

19

There is ____% mortality seen with Enterohemorrhagic E. coli. There are ____ fatal cases per year.

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54
Q

19

Most isolates of Enterohemorrhagic E. coli are serotype ______.

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55
Q

19

What is the lab diagnosis used for Enterhemorrhagic E. coli?

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56
Q

19

The treatment for enterohemorrhagic DNA is _____. Do not use ______!

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57
Q

22

What causes gastroenteritis?

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58
Q

22

Gastroenteritis has a ____ hour incubation period and is ____.

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59
Q

22

What are 4 symptoms seen in gastroenteritis?

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60
Q

22

Gastroenteritis accounts for ____% of all food borne infections.

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61
Q

23

What causes enteric fever (typhoid fever)

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62
Q

23

What are 6 symptoms of enteric fever?

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63
Q

24

What causes bacteremia with or without gastroenteritis?

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64
Q

24

What are 2 predisposing factors to bacteremia caused by Salmonella?

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65
Q

25

There are an estimated _____ cases per year of Salmonella in the US.

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66
Q

25

There are an estimated ____ fatal cases per year of Salmonella.

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67
Q

25

In what age group and season is Salmonella most commonly seen?

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68
Q

25

What are two sources of Salmonella?

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69
Q

25

What is the most common of the 6 subspecies of Salmonella?

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70
Q

26

What is required for pathogenes of Salmonella?

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71
Q

26

Salmonella invades _____ cells.

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72
Q

26

Salmonella has bacteremic spread or control by ______ tissue.

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73
Q

29

_____ therapy can be used for serious and/or disseminated Salmonella infections.

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74
Q

29

What does Shigella cause?

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75
Q

31

What is a key clinical manifestation of Shigellosis?

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76
Q

32

What is the source for Shigella?

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77
Q

34

What is the inoculum of Shigella compared to that of Salmonella?

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78
Q

34

Shigella invades _______ cells.

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79
Q

34

How is Shigella spread?

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80
Q

34

Shigella causes damage to the _______.

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81
Q

34

Shigella rarely involves the ______.

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82
Q

35

What is used to prevent spread of Shigella?

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83
Q

36

What are two major symptoms of Yersina enterocolitica infection?

A
84
Q

36

Yersina enterocolitica is distributed ______.

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85
Q

36

Yersina entercolitica can be ingested through ______, ______, and ______.

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86
Q

37

What does Yersina pestis cause?

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87
Q

37

What are four symptoms of bubonic plague?

A
88
Q

37

What is the mortality percentage for bubonic plague?

A
89
Q

37

What is one symptom caused by pneumonic Yersina pestis?

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90
Q

40

What is the source of Yersina pestis?

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91
Q

40

There are ______ reported cases per year worldwide of Yersina pestis.

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92
Q

40

There are ____ cases per year in the US of Yersina pestis.

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93
Q

40

Yersina pestis (pneumonic) is transmitted ______.

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94
Q

42

What is one thing that is cultured with Yersina pestis?

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95
Q

44

Klebsiella, Enterobacter, Serratia, Proteus,
Citrobacter, Morganella are all examples of what type of bacteria?

A
96
Q

44

What are 4 types of infections caused by Enterobacteriaceae?

A
97
Q

44

What are two sources of Enterobacteriaceae?

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98
Q

44

Enterobacteriaceae are usually _____ and often ______.

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99
Q

44

What is the treatment for Enterobacteriaceae?

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100
Q

45

Pseudomas is a _____ group.

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101
Q

45

Pseudomonas is found in what 5 places?

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102
Q

45

Pseudomonas are _____ and _______pathogens.

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103
Q

45

Are pseudomonas antibiotic resistant?

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104
Q

46

Pseudomonas are similar to _____ in many ways.

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105
Q

46

What are three types of Pseudomonas?

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106
Q

47

Is pseudomonas aeruginosa oxidase positive or negative?

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107
Q

47

Is pseudomnonas aeruginose oxidase positive or negative?

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108
Q

47

Pseudomonas aeruginosa has a _______ pigment and a _____ odor.

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109
Q

47

Is pseudomonas aeruginosa antibiotic resistant or not?

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110
Q

47

What are three places that psuedomonas aeeruginosa can be found?

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111
Q

47

Pseudomonas aeruginosa colonizes ______.

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112
Q

48

Pseudomonas aeruginosa pathogenesis requires _________.

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113
Q

48

What is the name of the Pseudomonas aeruginosa caosule?

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114
Q

48

What enzymes are involved in pathogenesis of pseudomonas aeruginosa?

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115
Q

48

What is the exotoxin in pseudomonas aeruginosa and what does it inhibit?

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116
Q

50

What is the general shape of pseudomonas aeruginosa?

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117
Q

51

What are 6 risk factors for disease with psuedomonas aeruginosa?

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118
Q

52

Pseudomonas aeruginosa is seen in ______ contamination.

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119
Q

54

What is the disease associated with pseudomonas aeruginosa?

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120
Q

54

Bacteremia by pseudomonas aeruginosa is the ____ most common cause of _______.

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121
Q

55

What is an example of a skin lesion associated with pseudomonas aeruginosa?

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122
Q

57

What are 3 diseases associated with pseudomonas aeruginosa?

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123
Q

58

What is the lab diagnosis for pseudomonas aeruginosa? What three things are being looked for?

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124
Q

59

What type of bacteria is Burkhoderia cepacia?

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125
Q

59

Is Burkholderia cepacia aerobic?

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126
Q

59

Burkholderia cepacia is glucose _______.

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127
Q

59

Burkholderia cepacia is resistant to ______.

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128
Q

59

Burkholderia cepacia was first described by Burkholder in 1950 as a pathogen of ______.

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129
Q

59

Burkholderia cepacia is a highly virulent organism known as the ______.

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130
Q

59

Burkholderia cepacia is commonly isolated from ____, _____, _______, and survives for ______.

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131
Q

60

What are two diseases caused by Burkholderia cepacia?

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132
Q

________ are susceptible to Burkholderia cepacia?

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133
Q

60

What are 3 diseases that Burkholderia cepacia are involved in?

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134
Q

61

Stenotrophomonas maltophilia causes _____ infections.

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135
Q

61

Stenotrophomonas maltophilia is seen in the _____ and _____.

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136
Q

61

What is the treatment for stenotrophomonas maltophilia?

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137
Q

62

S. maltophiliais is a ______ organism.

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138
Q

137

S. maltophiliais in a hospital setting is isolated from what 4 things?

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139
Q

137

S. maltophiliais is resistant to newer-generation _______.

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