Exam 3 Epithelial Tumors

Question 1

Epithelial Tumors

Answer 1

Epithelial tumors in the oral cavity can be
derived from
1) squamous epithelium
2) salivary gland epithelium
3) odontogenic epithelium

Question 2

What are the 3 main types of oral cancer?

Answer 2

• Sarcoma- malignant: supportive and connective tissue
• Carcinoma- malignant: Epithelial tissue
• Adenocarcinoma- maligant: Submucosal glands

Question 3

What are the 3 benign tumors?

Answer 3

• Papilloma
• Keratoacanthoma
• Melanocytic Nevi

Question 4

Whhat are the premalignant tumors?

Answer 4

• Leukoplakia
• Erythroplakia
• Actinic Keratosis

Question 5

What are the malignant tumors?

Answer 5

• Basal cell carcinoma
• Verrucous Carcinoma
• Squamous Cell Carcinoma
• Malignant Melanoma

Question 6

What is a papilloma?

Answer 6

• Cause: Low risk HPV
• M=F
• Soft palate and Tongue
• Exophytic fingerlike projection

Question 7

What HPV causes papillomas?

Answer 7

About 24 infects the oral cavity
- HPV 2,4,6, and 40- verruca vulgaris (wart)
- HPV 16, 18, 31, 33, 45 w/ neoplastic lesions

Question 8

Answer 8

Papilloma

Question 9

Answer 9

Papilloma

Question 10

Answer 10

Verruca Vulgaris

Question 11

Answer 11

Warts / Condyloma acuminatum

Question 12

What is a keratoacanthoma?

Answer 12

• Endophytic lesion (finger-like projection)
• Sharply circumscribed with central keratin plug/crater
• deveopls rapidly 1-3 months
• Goes up to 2.0-2.5 cm
• Occur on Sun-exposed skin
• Ages 50 or older

Question 13

What increases the thickness of the stratum spinosum layer?

Answer 13

Acanthosis

Question 14

Answer 14

keratoacanthoma

Question 15

Melanocytic Nevi

Answer 15

• Pigmented lesion can be exophytic collect of melanocytes
• Commonly named **freckle **
• 50 or older are at higher risk for skin cancer
• Check A, B, C, D, E

Question 16

What are the A B C D E ?

Answer 16

Question 17

Answer 17

Melanocytic Nevi

Question 18

What is Leukoplakia?

Answer 18

• White plaque that cannot be wiped off
• Can also be hyperkeratosis, Hyperplasis, Dysplasia or squamous cell carcinoma

Question 19

Answer 19

Leukoplakia

Question 20

What is Leukoedema?

Answer 20

• Translucent- grayish white film within the buccal mucosa
• Bilaterial
• **Disapperas when stretched **
  *

Question 21

Answer 21

Leukoedema

Question 22

Eythroplakia is?

Answer 22

• Describes a lesion as smooth, red patch or velvety patch
• Can be a mixture/speckled leukoplakia ( white and red)

Question 23

Eythroplakia is not common as? But associated with?

Answer 23

Leukoplakia
Associated with: Dysplasia or squamous carcinoma

Question 24

What must be performed for eythroplakia?

Answer 24

Biopsy

Question 25

Answer 25

erythroplakia

Question 26

What is Actinic Cheilitis?

Answer 26

* Pre-neoplastic * Changes in epithelium of the lips due to prolonged sun exposure * vermilion border becomes fuzzy and puffy * Chronic ulcers develop that stops healing process

Question 27

Answer 27

Actinic Cheilitis

Question 28

Actinic Keratosis

Answer 28

* Most common type of precancerous skin leasion * Scaly crusty patches * Locations: Back of hands, cheek, forehead, ear, and lower lip * Caused by long term sun exposure

Question 29

Answer 29

Actinic Keratosis

Question 30

What is basal cell carcinoma ?

Answer 30

* Neoplastic * associated with sun exposure * Age: 40 and over Hair bearing ares starts as papule then gets big Rarely metastasis * nonhealing ulcer rolled borders

Question 31

Answer 31

Basal Cell Carcinoma

Question 32

What is Verrucous Carcinoma?

Answer 32

* **Warty** , exophytic, keratinized Associated with ** tobacco ** users * Most common areas: Vestibule, buccal mucosa * slow growing mass * papillary projections

Question 33

Answer 33

Verrucous Carcinoma

Question 34

Answer 34

Verrucous Carcinoma

Question 35

Squamous Cell Carcinoma

Answer 35

* Most Common maligancy in the oral cavity * age 40 years and over * M more than F * Smoking, and alcohol are risk factors * Common sitesL: Floor of Mouth, tongue, lips soft palate, gingival ridge, buccal mucosa * Exophytic mass * Ulcertated

Question 36

What does early squamous cell carcinomas presents as ?

Answer 36

Leukoplakias and erythroplakias

Question 37

Answer 37

squamous cell carcinomas

Question 38

Answer 38

squamous cell carcinoma

Question 39

What is Melanoma?

Answer 39

* Melanocytes occuring on skin and mucosa * developmental * has nevus cells * Hard palate and buccal mucosa

Question 40

Answer 40

Melanoma

Question 41

Metastatic Tumors

Answer 41

* Tumors in the oral cavity can be a result of cancer elsewhere in the body metastasizing * Most common site is mandible