Exam 3 Epithelial Tumors Flashcards

1
Q

Epithelial Tumors

A

Epithelial tumors in the oral cavity can be
derived from
1) squamous epithelium
2) salivary gland epithelium
3) odontogenic epithelium

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2
Q

What are the 3 main types of oral cancer?

A
  • Sarcoma- malignant: supportive and connective tissue
  • Carcinoma- malignant: Epithelial tissue
  • Adenocarcinoma- maligant: Submucosal glands
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3
Q

What are the 3 benign tumors?

A
  • Papilloma
  • Keratoacanthoma
  • Melanocytic Nevi
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4
Q

Whhat are the premalignant tumors?

A
  • Leukoplakia
  • Erythroplakia
  • Actinic Keratosis
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5
Q

What are the malignant tumors?

A
  • Basal cell carcinoma
  • Verrucous Carcinoma
  • Squamous Cell Carcinoma
  • Malignant Melanoma
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6
Q

What is a papilloma?

A
  • Cause: Low risk HPV
  • M=F
  • Soft palate and Tongue
  • Exophytic fingerlike projection
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7
Q

What HPV causes papillomas?

A

About 24 infects the oral cavity
- HPV 2,4,6, and 40- verruca vulgaris (wart)
- HPV 16, 18, 31, 33, 45 w/ neoplastic lesions

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8
Q
A

Papilloma

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9
Q
A

Papilloma

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10
Q
A

Verruca Vulgaris

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11
Q
A

Warts / Condyloma acuminatum

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12
Q

What is a keratoacanthoma?

A
  • Endophytic lesion (finger-like projection)
  • Sharply circumscribed with central keratin plug/crater
  • deveopls rapidly 1-3 months
  • Goes up to 2.0-2.5 cm
  • Occur on Sun-exposed skin
  • Ages 50 or older
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13
Q

What increases the thickness of the stratum spinosum layer?

A

Acanthosis

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14
Q
A

keratoacanthoma

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15
Q

Melanocytic Nevi

A
  • Pigmented lesion can be exophytic collect of melanocytes
  • Commonly named **freckle **
  • 50 or older are at higher risk for skin cancer
  • Check A, B, C, D, E
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16
Q

What are the A B C D E ?

A
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17
Q
A

Melanocytic Nevi

18
Q

What is Leukoplakia?

A
  • White plaque that cannot be wiped off
  • Can also be hyperkeratosis, Hyperplasis, Dysplasia or squamous cell carcinoma
19
Q
A

Leukoplakia

20
Q

What is Leukoedema?

A
  • Translucent- grayish white film within the buccal mucosa
  • Bilaterial
  • **Disapperas when stretched **
    *
21
Q
A

Leukoedema

22
Q

Eythroplakia is?

A
  • Describes a lesion as smooth, red patch or velvety patch
  • Can be a mixture/speckled leukoplakia ( white and red)
23
Q

Eythroplakia is not common as? But associated with?

A

Leukoplakia
Associated with: Dysplasia or squamous carcinoma

24
Q

What must be performed for eythroplakia?

A

Biopsy

25
Q
A

erythroplakia

26
Q

What is Actinic Cheilitis?

A
  • Pre-neoplastic
  • Changes in epithelium of the lips due to prolonged sun exposure
  • vermilion border becomes fuzzy and puffy
  • Chronic ulcers develop that stops healing process
27
Q
A

Actinic Cheilitis

28
Q

Actinic Keratosis

A
  • Most common type of precancerous skin leasion
  • Scaly crusty patches
  • Locations: Back of hands, cheek, forehead, ear, and lower lip
  • Caused by long term sun exposure
29
Q
A

Actinic Keratosis

30
Q

What is basal cell carcinoma ?

A
  • Neoplastic
  • associated with sun exposure
  • Age: 40 and over
    Hair bearing ares
    starts as papule then gets big
    Rarely metastasis
  • nonhealing ulcer rolled borders
31
Q
A

Basal Cell Carcinoma

32
Q

What is Verrucous Carcinoma?

A
  • Warty , exophytic, keratinized
    Associated with ** tobacco ** users
  • Most common areas: Vestibule, buccal mucosa
  • slow growing mass
  • papillary projections
33
Q
A

Verrucous Carcinoma

34
Q
A

Verrucous Carcinoma

35
Q

Squamous Cell Carcinoma

A
  • Most Common maligancy in the oral cavity
  • age 40 years and over
  • M more than F
  • Smoking, and alcohol are risk factors
  • Common sitesL: Floor of Mouth, tongue, lips soft palate, gingival ridge, buccal mucosa
  • Exophytic mass
  • Ulcertated
36
Q

What does early squamous cell carcinomas presents as ?

A

Leukoplakias and erythroplakias

37
Q
A

squamous cell carcinomas

38
Q
A

squamous cell carcinoma

39
Q

What is Melanoma?

A
  • Melanocytes occuring on skin and mucosa
  • developmental
  • has nevus cells
  • Hard palate and buccal mucosa
40
Q
A

Melanoma

41
Q

Metastatic Tumors

A
  • Tumors in the oral cavity can be a result of cancer elsewhere in the body metastasizing
  • Most common site is mandible