Exam 3 Epithelial Tumors Flashcards
Epithelial Tumors
Epithelial tumors in the oral cavity can be
derived from
1) squamous epithelium
2) salivary gland epithelium
3) odontogenic epithelium
What are the 3 main types of oral cancer?
- Sarcoma- malignant: supportive and connective tissue
- Carcinoma- malignant: Epithelial tissue
- Adenocarcinoma- maligant: Submucosal glands
What are the 3 benign tumors?
- Papilloma
- Keratoacanthoma
- Melanocytic Nevi
Whhat are the premalignant tumors?
- Leukoplakia
- Erythroplakia
- Actinic Keratosis
What are the malignant tumors?
- Basal cell carcinoma
- Verrucous Carcinoma
- Squamous Cell Carcinoma
- Malignant Melanoma
What is a papilloma?
- Cause: Low risk HPV
- M=F
- Soft palate and Tongue
- Exophytic fingerlike projection
What HPV causes papillomas?
About 24 infects the oral cavity
- HPV 2,4,6, and 40- verruca vulgaris (wart)
- HPV 16, 18, 31, 33, 45 w/ neoplastic lesions
Papilloma
Papilloma
Verruca Vulgaris
Warts / Condyloma acuminatum
What is a keratoacanthoma?
- Endophytic lesion (finger-like projection)
- Sharply circumscribed with central keratin plug/crater
- deveopls rapidly 1-3 months
- Goes up to 2.0-2.5 cm
- Occur on Sun-exposed skin
- Ages 50 or older
What increases the thickness of the stratum spinosum layer?
Acanthosis
keratoacanthoma
Melanocytic Nevi
- Pigmented lesion can be exophytic collect of melanocytes
- Commonly named **freckle **
- 50 or older are at higher risk for skin cancer
- Check A, B, C, D, E
What are the A B C D E ?
Melanocytic Nevi
What is Leukoplakia?
- White plaque that cannot be wiped off
- Can also be hyperkeratosis, Hyperplasis, Dysplasia or squamous cell carcinoma
Leukoplakia
What is Leukoedema?
- Translucent- grayish white film within the buccal mucosa
- Bilaterial
- **Disapperas when stretched **
*
Leukoedema
Eythroplakia is?
- Describes a lesion as smooth, red patch or velvety patch
- Can be a mixture/speckled leukoplakia ( white and red)
Eythroplakia is not common as? But associated with?
Leukoplakia
Associated with: Dysplasia or squamous carcinoma
What must be performed for eythroplakia?
Biopsy
erythroplakia
What is Actinic Cheilitis?
- Pre-neoplastic
- Changes in epithelium of the lips due to prolonged sun exposure
- vermilion border becomes fuzzy and puffy
- Chronic ulcers develop that stops healing process
Actinic Cheilitis
Actinic Keratosis
- Most common type of precancerous skin leasion
- Scaly crusty patches
- Locations: Back of hands, cheek, forehead, ear, and lower lip
- Caused by long term sun exposure
Actinic Keratosis
What is basal cell carcinoma ?
- Neoplastic
- associated with sun exposure
- Age: 40 and over
Hair bearing ares
starts as papule then gets big
Rarely metastasis - nonhealing ulcer rolled borders
Basal Cell Carcinoma
What is Verrucous Carcinoma?
-
Warty , exophytic, keratinized
Associated with ** tobacco ** users - Most common areas: Vestibule, buccal mucosa
- slow growing mass
- papillary projections
Verrucous Carcinoma
Verrucous Carcinoma
Squamous Cell Carcinoma
- Most Common maligancy in the oral cavity
- age 40 years and over
- M more than F
- Smoking, and alcohol are risk factors
- Common sitesL: Floor of Mouth, tongue, lips soft palate, gingival ridge, buccal mucosa
- Exophytic mass
- Ulcertated
What does early squamous cell carcinomas presents as ?
Leukoplakias and erythroplakias
squamous cell carcinomas
squamous cell carcinoma
What is Melanoma?
- Melanocytes occuring on skin and mucosa
- developmental
- has nevus cells
- Hard palate and buccal mucosa
Melanoma
Metastatic Tumors
- Tumors in the oral cavity can be a result of cancer elsewhere in the body metastasizing
- Most common site is mandible
