Exam 2 - Feline Upper Respiratory Tract Infection Flashcards

1
Q

what does ‘acutely infected’ mean?

A

recently infected cat that may or may not show clinical signs & the long-term outcome is unclear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what does ‘recovered’ cat mean in regards to upper respiratory infections?

A

animal is recovered from clinical signs & may or may not still be contagious to other animals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what does ‘carrier’ cat mean in regards to upper respiratory infections?

A

cat who sheds the infectious agents in absence of clinical signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the etiology of feline herpesvirus?

A

dsDNA enveloped virus that is fragile in the environment & easily disinfected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T/F: there is very little strain variation within cats with herpes virus & will affect other cats/felidae

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/F: once infected with herpes, always infected

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the importance of latent carriers in herpes virus?

A

nearly all cats become latent carriers, so while clinical signs are absent, stress can lead to recurrence of shedding & potential recrudescent disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

why can cats get calicivirus more than once?

A

large number of antigenically varied strains with different virulence among strains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the etiology of feline calicivirus?

A

small, unenveloped ssRNA virus that is more durable in the environment than herpes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what helps make calicivirus more successful in terms of virulence?

A

some cats remain lifelong carriers & the chronic carriers will shed more or less constantly often without clinical signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the recovery & shedding seen with calicivirus?

A

after recovery from acute infection - most cats will shed for weeks

over time the proportion of shedders declines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T/F: b. bronchiseptica can be both a primary & secondary pathogen in cats

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when do cats shed b. bronchiseptica?

A

shedding more likely in cats with clinical signs - stressed out animals, & reinfection in the face of underlying viral infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T/F: seroprevalence suggests that up to 50% of cats have recent exposure to b. bronchiseptica & 10% are shedding the pathogen at any given time

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the etiology of chlamydophila felis?

A

primitive bacteria - obligate intracellular, has a cell wall, & lacks essential metabolic pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the 2 forms of chlamydophila felis?

A

elementary body in the environment

reticulate body in the host cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is the infectious form of chlamydophila felis?

A

elementary body in the environment - very resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what form of chlamydophila felis has no cell wall & replicates by budding/fission?

A

reticulate body in the host cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

how is chlamydophila felis spread?

A

conjunctival/ocular secretions, gi/genital mucosa in some adults, & kittens may be exposed at parturition or maternal care

close contact, fomites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

T/F: by age 5, infection with chlamydophila felis is unlikely in cats

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what age animals are typically affected by chlamydophila felis?

A

young cats - < 1 year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what animals are generally affected by feline URIs?

A

young cats & feral cats

think immunosuppressed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is the typical clinical presentation of cats with a URI?

A

lethargy, inappetence, sneezing, nasal discharge, fever in most cases, conjunctivitis, & ocular discharge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what is associated with the lightening bolt ulcer in cats?

A

herpes virus - ulcerative keratitis because of direct viral damage

25
Q

what virus has strains that are associated with pneumonia, polyarthritis, & severe systemic disease?

A

calicivirus

26
Q

what virus may be associated with simultaneous illness in the family dog?

A

bordetella

27
Q

what organism is strongly associated with conjunctivitis & potential systemic illness?

A

chlamydophila felis

28
Q

what virus is associated with ulcerated lesions on the tongue in cats?

A

calicivirus

29
Q

why is serology useless in feline URI?

A

likely all animals have it, so they will have antibodies present

30
Q

what zoonotic concerns are associated with chlamydophila felis?

A

c. psittaci is zoonotic

c. pneumoniae - possibly linked to coronary artery disease in humans

31
Q

what are components of the supportive & symptomatic care for feline URIs?

A

clean, warm, dry air is especially important for neonates

steam therapy, aromatic foods, plenty of water & rest, & outpatient whenever possible

32
Q

what medications can be given for a cat with an URI?

A

doxycycline - pre-made elixir that is smoothly mixed to avoid strictures

ophthalmic oxytetracycline for suspected c. felis conjunctivitis

33
Q

why may antibiotics be used for cats with URIs?

A

viral infections can predispose the patient to secondary bacterial infections

34
Q

T/F: topical ocular antivirals may be used for a patient with herpes keratitis

A
35
Q

what is the goal of non-sterilizing immunity?

A

vaccination lessens duration, severity, or frequency of clinical signs of disease

36
Q

what vaccines aim for the goal of non-sterilizing immunity?

A

feline herpesvirus & feline calicivirus

37
Q

T/F: non-sterilizing immunity parallels vaccines against the flu

A

true

38
Q

as far as prevention goes for cats in shelters, what should be the vaccine protocol for preventing URIs?

A

vaccinate as many as possible & as early as possible after admission

39
Q

as far as prevention retrovirus-infected cats, what should be the vaccine protocol for preventing URIs?

A

generally vaccinate with core agents if cats are well & keep them indoors & away from other cats to minimize risks

40
Q

as far as prevention goes for cats with a history of injection site sarcomas, what should be the vaccine protocol for preventing URIs?

A

discontinue further injectable vaccines

41
Q

what principles make a vaccine core?

A

all cats are at substantial risk of serious disease

an effective vaccine exists

zoonotic potential plays a role

42
Q

what vaccines are considered core for cats?

A

rabies, panleukopenia, herpesvirus, & calicivirus

43
Q

what are the principles of non-core vaccines?

A

low-level risk for most cats & or mild/moderate disease for most cats

select population at risk

vaccine issues play a role

44
Q

what vaccines are considered non-core for cats?

A

FeLV, FIV, bordetella, & chlamydophila felis

45
Q

T/F: feline URTI vaccines reduce severity & duration of clinical signs

A

true

46
Q

why don’t feline URTI vaccines prevent infection?

A

non-sterilizing immunity is used

vaccinates may still shed infectious agents

vaccinates may become chronic carriers

47
Q

what is sterilizing immunity?

A

vaccination completely prevents subsequent infection

48
Q

what are side effects of IN vaccines?

A

can induce mild clinical signs which may mimic a URTI

49
Q

what vaccine is associated with febrile limping syndrome after it’s been given?

A

calicivirus & c. felis vaccines

50
Q

T/F: injection site sarcomas are possible in cats from any injection

A

true

51
Q

what is the strongest indication for giving a vaccine for chlamydophila felis?

A

group setting - cattery, colony, household with documented disease history

52
Q

what products are available for vaccinating against chlamydophila felis?

A

inactivated adjuvanted & MLV non-adjuvanted

53
Q

what is the goal when vaccinating for chlamydophila felis?

A

decrease frequency & severity of disease

54
Q

how often should vaccines for chlamydophila felis be boostered?

A

annually

55
Q

how often should vaccines for calicivirus be boostered?

A

every 3 years

56
Q

what products are available for vaccinating against calicivirus?

A

MLV & inactivated products for SQ & IN routes

generally effective by 9 weeks

57
Q

when is the final dose of the initial series given when vaccinating against calicivirus?

A

16-20 weeks old

58
Q

how often should vaccines for herpes be boostered?

A

every 3 years

59
Q

what products are available for vaccinating against herpesvirus?

A

MLV & inactivated products for SQ & IN routes

generally effective by 9 weeks