Exam 2 development of the NS

Question 1

What induces formation of the neural plate?

Answer 1

Notochord

Question 2

What layer of the trilaminar disc does the neural plate/tube come from?

Answer 2

Ectoderm

Question 3

What fluid fills the neural tube?

Answer 3

Amniotic fluid

Question 4

List the development of the neural tube/neural crest cells

Answer 4

Neural plate –> Neural folds –> Neural groove –> Neural tube and neural crest cells

Question 5

What develops if the cranial neuropore fails to close?

Answer 5

Encepholocoel

Question 6

What develops if the caudal neuropore fails to develop?

Answer 6

Spina bifida

Question 7

What part of the NS does the neural tube form?

Answer 7

Brain and spinal cord

Question 8

What part of the NS does the neural crest form?

Answer 8

PNS and many other non-neural derivatives

Question 9

What part of the NS does the neural canal form?

Answer 9

Ventricular system (ventricles of brain and central canal of spinal cord

Question 10

What does neuroepithelial cells differentiate into?

Answer 10

Neurons whose cell bodies lie in the CNS and macroglial cells in the spinal cord

Question 11

What separates the alar plate and the basilar plate?

Answer 11

sulcus limitans

Question 12

What are the different zones of maturation during the maturation of the neural tube

Answer 12

ventricular zone, intermediate zone, marginal zone

Question 13

Describe the ventricular zone of the neural tube

Answer 13

Neuroepithelial cells; stem cells that form into oligodendrocytes, also become neural cells, glial cells and ependyma

Question 14

Describe the intermediate zone of the neural tube

Answer 14

Differentiate and become the neurons/gray matter

Question 15

Describe the marginal zone of the neural tube

Answer 15

The axons/white matter of the CNS

Question 16

What layer of the neural tube develops into the alar plate and the basal plate?

Answer 16

Intermediate layer

Question 17

What kind of neurons are found in the alar plate?

Answer 17

Second order sensory neurons

Question 18

What kind of neurons are found in the basilar plate?

Answer 18

Motor neurons

Question 19

Where are the first order sensory neurons? What kind of neuron is it?

Answer 19

Dorsal root ganglion, pseudounipolar

Question 20

What occurs in the floor plate of the neural tube?

Answer 20

Decussation of the tracts

Question 21

What kind of cells are found in the intermediate layer?

Answer 21

Autonomic cells

Question 22

Where do axons of ventral horn neurons synapse?

Answer 22

Skeletal muscle

Question 23

Where do axons of lateral horn neurons synapse?

Answer 23

Autonomic ganglia

Question 24

What order neurons are found in the dorsal root ganglia?

Answer 24

First order neurons

Question 25

What is special in terms of myelination of cells that can cross from the CNS to the PNS?

Answer 25

Myelinated by both Schwann cells and Oligodendrocytes

Question 26

When does the neural tube completely close?

Answer 26

Late 3rd week

Question 27

At was level of somite does the neural tube develop into the brain?

Answer 27

Rostral to the 4th Somite

Question 28

What secondary vesicles does the Forebrain develop into?

Answer 28

Telencephalon, Diencephalon

Question 29

What secondary vesicle does the midbrain develop into?

Answer 29

mesenceophalon

Question 30

What secondary vesicles does the hindbrain develop into?

Answer 30

Metencephalon, myelencephalon

Question 31

What does the telencephalon develop into?

Answer 31

Cerebral cortex, corpus striatum, olfactory bulbs

Question 32

What does the diencephalon develop into?

Answer 32

thalamus, hypothalamus, epithalamus, subthalamus

Question 33

What does the mesencephalon develop into?

Answer 33

tectum, tegmentum, cerebral peduncles

Question 34

What does the metenceophalon develop into?

Answer 34

pons, cerebellum

Question 35

What does the myelencephalon develop into?

Answer 35

medulla

Question 36

What does the caudal neural tube develop into?

Answer 36

The spinal cord

Question 37

Where does the pontine flexure develop?

Answer 37

Between metencephalon and myelencephalon

Question 38

Where does the cephalic flexure develop?

Answer 38

Mesencephalon

Question 39

Where does the cervical flexure develop?

Answer 39

myelencephalon and spinal cord

Question 40

Where is the sulcus limitans in the fourth ventricle

Answer 40

On the floor between basal and alar plates