Development of skull- Ach Flashcards
Does the base of the skull come from paraxial or lateral plate mesoderm?
Paraxial mesoderm
What part of the skull is the neurocranium? What bones form it?
All around the brain; ethmoid, spenoid, occipital, petrous temporal, temproal-mastoid, frontal, parietal, occipital-squamos
What part of the skull is the viscerocranium? What bones form it?
Most of the face/jaw; malleus, incus, stapes, hyoid, temporal-styloid, maxilla, zygoma, temporal-squamos, mandible
T/F: bones of the face and skull come from neuroectoderm?
True
True/false: face bones originate from pharyngeal arches?
True
What is the term for premature closure of sutures?
Craniosynostosis
What is premature closure of sagittal sutures called? What does it produce?
Scaphocephaly; long, narrow head
What is premature closure of coronal and lambdoidal sutures called? What does it produce?
Oxycephaly; tower skull
What is premature closure of bilateral coronal suture called? What does it produce?
Brachycephaly; wide skull
What is closure of one side of coronal or lambdoidal suture called? What does it produce?
Plagiocephaly; asymetric or twisted head
What is premature closure of frontal suture called? What does it produce?
Trigonocephaly; pointed forehead
What is the mutation of Apert Syndrome? What is the inheritance pattern?
mutation is fibroblast growth factor receptor 2 gene; autosomal dominant
What is Apert syndrome?
Under-developed mid-face, symmetric syndactyly, hearing loss, short stature, possible slow intellectual development
What is Crouzon syndrome?
Similar to Apert, but only craniofacial abnormalities
What is microcephaly?
small head usually due to underdeveloped brain, individuals are mentally deficient
