Exam 1 Review Flashcards

1
Q

Describe the CNS

A

Encased in the bones of the skull and vertebral column
Grossly consists of the brain (cerebrum, cerebellum, brainstem and subcortical structures) and spinal cord
Control center, integration, processing

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2
Q

Describe the PNS

A

Spinal nerves –31 pairs
Cranial nerves—12 pairs
Carrying information to and from the central nervous system
And the autonomic nervous system (ANS)
Involuntary, automatic

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3
Q

Higher mental processes

A

FRONTAL

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4
Q

Processes sensory information

A

Parietal

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5
Q

Processes visual information

A

occipital

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6
Q

Processes auditory information

A

temporal

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7
Q

Involved in consciousness
May be implicated in expressive aphasia

A

insula

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8
Q

Processes memory and emotion

A

limbic lobe

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9
Q

motor info going to muscles or glands

A

efferent/descending

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10
Q

sensory info going to receptor organs

A

afferent/ascending

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11
Q

cervical vertebrae and nerves

A

7 v 8 nerves

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12
Q

thoracic vertebrae and nerves

A

12

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13
Q

lumbar vertebrae and nervesf

A

5

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14
Q

sacral vertebrae and nerves

A

1 fused, 5 nerves

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15
Q

coccyx vertebrae and nerves

A

1

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16
Q

what are the 3 layers of meninges

A

dura, arachnoid, pia

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17
Q

what are the layers of the dura

A

Meningeal layer (attaches to arachnoid) and endosteal layer (this outer layer serves as the periosteum)
Dural layers are tightly attached to one another
Endosteal layer adheres to inside of the skull

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18
Q

what causes massive bleeding if a meningeal artery is torn.

A

high arterial blood pressure

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19
Q

what is the falx cerebri

A

dura that dips in and separates l and r hemisphere and doesn’t go all the way in because of the cc (connection bw two hemispheres

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20
Q

what is the protection of the CNS?

A

skin and scalp
vertebral colum and skull
meninges

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21
Q

describe the tentorium cerebelli

A

separates the cerebellum from the cerebral hemispheres
near cerebellum (tent over it)
helps keep parietal and occipital from squishing down on the cerebellum
holds these up to avoid this

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22
Q

below tectorium (cerebellum and bs) supratentorial

A

infratentorial

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23
Q

above tent (cerebral hemispheres)

A

supratentorial

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24
Q

the opening where the brainstem passes into the cerebrum
tent needs opening
BS passes up into cerebral hemispheres

A

tentorial notch

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25
what type of lesions are better? supra or infra?
supratentorial lesions are better than infratentorial in the BS because all life sustaining things happens here and having a lesion can be fatal
26
why is the area of tentorial notch dangerous for concussions or head trauma?
area where concussion or head trauma - soft tissues are sheared at this notch against hard leather and can cause damage
27
Lies on the inner surface of the dura Web-like
arachnoid
28
what is in the subarachnoid space
csf
29
what is the arachnoid trabiculae
collagenous (collagen fibers) strands connect the arachnoid and the pia for suspension
30
what is the arachnoid villa
pressure sensitive straws or one way valves; one way valve taking high pressure CSF into villi to go to the sinuses and then dumped into other sinuses and out through the jugular vein
31
closely adheres to the CNS tissue, following the gyri and fissures
pia
32
ARe there meninges in the sc?
All of the meninges cover the spinal cord too Slight differences in how the dura and pia connect to the spinal cord, vertebrae and nerve roots Spinal dura is a single layer There is an epidural space in the spinal cord (the dura is not attached tightly to bone as in the skull) don’t want something tightly attached to something that has movement if it was attached to bone in spinal cord, we were tear it every time we moved Arachnoid layer and subarachnoid space are similar to those in the brain
33
what anchors the spinal cord
Lumbar cistern exists (pocket), denticulate ligament and filum terminale of pia and dural sheat
34
where can we do epidural injections without causing damage?
go into subarachnoid space in cauda equina and pull out CSF without damaging tissue in areas of lumbar cistern or filum terminale??
35
Spaces where the endosteal and meningeal layers of the dura separate Cavities
venous sinuses
36
end in jugular vein to drain used blood and fluids from the brain (cranial vault)
Transverse sinus, straight sinus, sigmoid sinus and a few more
37
collects used blood
inferior saggital sinus
38
largest of venous system
superior sagittal sinus
39
what is the drainage system to carry blood and CSF away from the brain and to be recycled in the systemic blood flow.
venous system
40
what tissue makes side of sinuses?
dura
41
describe an epidural hematoma
also called extradural and has “lemon”shape) occurs if the meningeal arteries are torn Most frequently after skull fractures (traumatic skull injury) Bleeding between the periosteum (endosteal layer of the dura) and the skull bones Death can occur within minutes if meningeal arteries are torn above dura bleeding bw dura and bone and pushes dura down to create pocket of blood here happens with meningeal artery tears this is the biggest concern with head trauma
42
describe subdural hematomas
“banana” shape) from dural venous sinus or vein attachment at the sinus (blood is beneath the dura) Rapid accelerations or decelerations of the head can cause the tearing of cerebral veins May be acute with fast symptoms like an epidural hematoma or very slow in producing symptoms underneath dura head injury from motorcycle accident can still cause problems like epidural but not as likely
43
describe subarachnoid hematomas
sometimes called subarachnoid hematoma More common Bleeding between the brain and the arachnoid (under the arachnoid) Bleeding is generally from veins—less pressure Can be from an artery From severe blow to the head or from a rupturing blood vessel in the brain (i.e. a ruptured aneurysm)
44
are arteries or veins under more pressure?
arteries needs pressure to pump up but veins drain more so with gravity down torn artery creates squirting artery
45
lemon shape bc the dura is adhering to bone and make a pocket
epidural hematoma
46
banana shape, following the contour of the subarachnoid space and cerebrum
subdural hematoma
47
List all the things that protect the CNS
Hard bony skull and vertebrae Meninges CSF for buoyancy and cushioning weighs less when it is sitting in fluid, provides cushion, protects because it is cushioning and protect from chemical homeostasis Protection from vibration, pressure, temperature Chemical barrier—blood brain barrier Regulation of temperature and function by the brain itself
48
what are the 3 major functions of the CSF
to keep the tissue buoyant, acting as a cushion acts as a vehicle for delivering nutrients to the brain and removing waste to flow between the cranium and spine and compensate for changes in intracranial blood volume
49
List the ventricles and the foramina and how the CSF is produced; and how it flows
CSF is produced by choroid plexus and flows from the 2 lateral ventricles through the interventricular foramina to the third ventricle and then through the cerebral aqueduct to the fourth ventricle and then out into the subarachnoid space The CSF flows from the two lateral ventricles (one in each hemisphere) through the paired interventricular foramina of Monro (holes) to the single midline third ventricle of the diencephalon (thalamus). From the third ventricle, CSF flows through the tube-like cerebral aqueduct of Sylvius in the midbrain to the fourth ventricle of the pons and medulla The CSF in the fourth ventricle can flow into the central canal which runs down the length of the spinal cord (This is usually closed in adults) CSF exits the fourth ventricle via the two lateral foramina of Luschka and the single median foramen of Magendie to enter the cisterna magna of the subarachnoid space. CSF circulates rostrally through the subarachnoid space to reach the superior sagittal sinus It then enters the venous blood flow via giant vacuole transport (sucked up) through the specialized arachnoid villi. The CSF mixes with the blood in the sinuses and is carried to the jugular vein to be recycled and be removed from the brain
50
when will CSF flow into the superior sagittal sinus?
When the CSF pressure is higher than the venous pressure
51
one way valves
arachnoid villa
52
what is the cisterna magna
space under cerebellum; widest part of subarachnoid space under cerebellum
53
the major responsible bacterial organism (formerly Haemophilus influenzae but H. influenzae vaccines lowered this rate) for bacterial meningitis
Streptococcus pneumoniae
54
Most common cause of acquired postlingual profound SNHL and ossification of the labyrinth
bacterial meningitis
55
how does infection reach the inner ear?
through cochlear aqueduct (links subarachnoid space to basal turn of scala tympani this explains why we see more high frequency hearing loss associated with it HL associated with this occurs as early as 48 hours after infection
56
Disruption of CSF circulation CSF pressure rises and ventricles expand
hydrocephalus
57
What can cause CSF?
Can be from excess CSF production, blockage of circulation or deficiency in reabsorption
58
what is the most common cause of hydrocephalus?
aqueductal stenosis - results from narrowing of cerebral aqueduct between the third and fourth ventricles in middle of the brain
59
what is communicating hydrocephalus?
This is when the lateral ventricles are still “communicating”/connected with the subarachnoid space and the problem is with reabsorption through the arachnoid villi or tentorial notch pressure from outside - sas is pressing down on the tissues occurs when flow is disrupted after it leaves the ventricles
60
what is noncommunicating hydrocephalus?
aka obstructive hydrocephalus occurs when the flow of csf is blocked among one or more of the narrow passages connecting the ventricles blockage could be due stenosis of the cerebral aqueduct or occlusion of the openings out of the 4th ventricle balloons from inside - CSF stuck in ventricles
61
what are the symptoms of NPH?
abnormal gait, incontinence, memory problems, dementia gait of individuals with NPH is distinct and appears as though their feet are glued to the floor as they try to ambulate; the gait has also been described as magnetic (Weiner, Constantini, Cohen, & Wisoff, 1995). NPH is one of the few reversible causes of dementia in older adults
62
describe NPH
usually a result from subarachnoid hemorrhage, head trauma, infection, tumor, or surgery complications Generally in patients over 60 Usually idiopathic NPH Slowly developing from gradual blockage of CSF
63
idiopathic
unknown cause
64
caused by drug or substance that interferes with development of the embryo or fetus
teratogenic
65
caused by dx, manner or tx of a physician
iatrogenic
66
what can nph be mistaken for?
Can be mistaken for Alzheimer disease or Parkinson disease
67
Can we treat NPH? if so, with what?
If NPH is correctly diagnosed and treated, the symptoms can resolve Tx may be ventriculoperitoneal shunt
68
what are the two main divisions of the neurovasculature?
carotid circulation vertebrobasilar circulation
69
ascends from left ventricle of heart
aorta
70
arise from aorta and subclavian arteries
common carotid and vertebral arteries
71
anterior supply
carotid
72
posterior supply
vertebral
73
arise from aorta
subclavian arteries
74
branch from subclavian and provide 20% of blood supply to CNS
vertebral arteries
75
branch off of subclavian on the right and aorta on the left
common carotid
76
begins at upper border of thyroid cartilage and ascends to reach base of the skull
internal carotid
77
enters at carotid canal (lacerum)
internal carotid
78
ophthalmic artery branches off from here and divides into many branches
internal carotid
79
also gives rise to middle cerebral arteries and anterior cerebral arteres and posterior communicating arteries
internal carotid
80
blood to brain eyes, etc
internal carotid
81
provide about 80% blood supply to telencephalon (hemispheres) and diencephalon (thalamus?)
internal carotid
82
arises opposite the upper border of thyroid cartilage, inclines backwards to space between neck and condyle of lower jaw and external auditory meatus
external carotid
83
divides into temporal and internal maxillary arteries
EC
84
supply neck face and base of skull blood to face and mouth
EC
85
supplies areas of the cerebellum, medulla and choroid plexus of the 4th ventricle Division of the vertebral arteries
PICA
86
one artery that runs along the anterior midline of the spinal cord division of vertebral arteries
ventral spinal artery
87
Larger on the left
vertebral arteries
88
what arises off of the vertebral arteries?
Posterior (dorsal) spinal arteries Anterior (ventral) spinal artery PICA
89
what arises off of the basilar artery?
AICA SCA posterior cerebral arteries
90
what branch off of the basilar artery supply inferior portion of cerebellum including the flocculus
AICA
91
what branch off of the basilar artery supply superior cerebellum, much of the caudal midbrain and rostral pons
SCA
92
what branch off of the basilar artery , at the level of the midbrain, supply caudal diencephalon, medial occipital lobe and inferior temporal lobe
posterior cerebral arteries
93
how the circle of Willis is formed and what is its value/purpose?
The circle of willis forms anastomoses (natural communication between 2 blood vessels) between the internal carotid arteries and the vertebrobasilar system of arteries on the ventral side of the brain. It is made up of: Anterior cerebral artery (left and right) Anterior communicating artery Internal carotid artery (left and right) Posterior cerebral artery (left and right) Posterior communicating artery (left and right) The circle of Willis functions to support and provide blood supply between the anterior and posterior cerebral circulations, serving as backup routes for blood flow if one link is blocked or otherwise compromised. It prevents neurological damage from loss of blood.
94
What areas are supplied by the anterior cerebral artery?
longitudinal fissure from frontal to back of parietal
95
What areas are supplied by the middle cerebral artery?
sylvian/lateral fissure, primary a1, temporal lobe
96
What areas are supplied by the posterior cerebral artery?
occipital lobe to lower gyri of temporal lobe
97
Where does the labyrinthine artery branch off from other arteries? Details of blood supply to the labyrinthine structures of the AVS
Internal auditory or labyrinthine arteries- directly from basilar artery or from anterior inferior cerebellar artery Lab A. -> C.C. & AVA -> AVA to L SCC, S SCC, & Utricle -> C.C. to PVA & Main Coch. -> M.C. to spiral ganglion, Organ of Corti & Stria Vasc. -> PVA to P SCC & Saccule
98
describe the blood supply to the SC
comes off the vertebral arteries posterior spinal arteries 2 run down back of SC anterior spinal artery (2 from vertebrals) one anterior runs along the anterior midline of the sc
99
what are chronic conditions that affect blood flow?
high cholesterol diabetes
100
a foreign body (blood clot) that travels within the body and can constrict blood flow (could be detached thrombus)
embolus
101
a blood clot, a lesion attached to the inner vessel wall, can block partially or fully the flow of blood. (attached)
thrombus
102
can a thrombus can break off and turn into an embolus?
yes
103
what is a plexus?
a large network of blood vessels
104
large amounts of blood escapes into surrounding tissues without clotting can have symptoms like strokes an escape of blood through ruptured or unruptured vessel walls
hemorrhage
105
small amounts of blood that escape into surrounding tissues causing bruising a localized mass of blood outside of blood vessels that is relatively or completely confined within an organ or tissue, a space or potential space; the blood is usually clotted
hematoma
106
most common cause of neurological deficits
Cerebrovascular (blood flow to cerebral structures) disease and accidents
107
necrotic region of tissue
infarct
108
what can strokes lead to if blood supply is not restored?
infarct
109
abrupt incident of vascular insufficiency
stroke
110
loss of blood supply due to mechanical blockage
ischemic stroke
111
what can cause an ischemic stroke?
thrombus or embolus
112
blood is blocked for a little bit and then gets broken up and clears itself allowing blood to flow through again
TIA
113
Is a stroke more dangerous in the infratentorial or supratentorial region?
more dangerious in infratentorial because BS has life managing functions (automatic things) and can go into a coma or life threatening injuries. Supra can just affect a little of something.
114
localized dilation of a blood vessel wall is weak and can rupture can be corrected surgically if detected while small
aneurysms
115
occur were cerebral arteries branch off of the circle of willis considered subarachnoid hemorrhage (when ruptures, blood spills into the space bw skull and brain)
berry aneurysm
116
Describe the signs of a stroke
B = Balance: Sudden loss of balance E = Eyes: Loss of vision in one or both eyes F = Face: Face droops on one side A = Arms: Arm drops when both arms are raised S = Speech: Speech is slurred or sounds different T = Time: Time to get help immediately
117
What is angiography?
medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers
118
what arteries from EC supply the outer ear?
posterior auricular arteries anterior auricular arteries
119
where does blood supply for peripheral ear structures come from
labyrinthine artery that comes from basilar or AICA directly off vertebral basilar
120
how do we make vertebral basilar and carotid connect?
with communicating arteries (posterior - come right off of IC, anterior )
121
why do we care about the circle?
provides alternative routes for blood to circulate if there is a blockage elsewhere safety valve will slowly widen over time doesnt work well for fast occlusions
122
Ophthalmic artery branches off this and divides into the many branches artery passes into the orbit via the optic canal.
internal carotid
123
Divides into temporal and internal maxillary arteries Branches—supply the neck, face and base of skull
external carotid
124
what branches of EC supply middle ear?
the occipital and/or posterior auricular arteries The deep auricular artery, a branch of the maxillary artery.
125
what branches of IC supply inner ear
labyrinthine artery, arising from either the anterior inferior cerebellar or the basilar artery
126
what is the bbb and why is it important
when arteries go down to arterials and capillaries to feed brain tissues, there are tight junctions large macromolecules cannot go through because things like viruses are these and this helps restrict access to the tissues controls the movement of substances from the general extracellular fluid of the body to the extracellular fluid of the brain strict def: tight junctions of endothelial cells that line capillaries in CNS
127
helps to protect cns
Arachnoid barrier layer
128
CSF-Brain interface
interface because fluid bathes the brain
129
what is Arteriovenous malformations and why does it cause a problem
tangle of blood vessels that connects arteries and veins in the brain causes problem because arteries are supposed to bring blood in and veins take it out and here they go together and not do their job can rupture due to delicate walls happens during development
130
cavities formed by the endosteal and meningeal layers of the dura mater
venous sinuses
131
the drainage system to carry blood and CSF away from the brain and to be recycled in the systemic blood flow.
venous sinuses
132
Briefly describe the drainage system of the venous sinuses
Veins of the cerebral cortex dump into the venous sinuses Sinuses such as the superior sagittal sinus (SSS), sigmoid sinus, straight sinus, inferior sagittal sinus, straight sinus, and cavernous sinuses also dump into the overall system for drainage Then to internal jugular veins and basilar venous complex around the base of the brain
133
Is plasticity a good thing?
yes, able to reorganize f the blood, like the circle of willis, if something can accommodate a change for the benefit of the brain
134
what is the great cerebral veil of galen
it is formed by the joining of the paired internal cerebral veins (the major deep veins) and it joins the inferior sagittal sinus to form the straight sinus
135
What are the functions of the skin?
Covering—about 2mm thick and weighs about 6 pounds Skin is largest organ—has more than two tissues Waterproof—to keep water in Barrier from foreign invasion Bacteria, viruses, fungi, protozoa, chemicals Protects from ultraviolet rays Heat control Sensory receptors Vitamin D/Hormone production Excretion
136
how does our skin protect against UV?
melanocytes produce melanin absorbs UV light
137
how does our skin protect with heat control?
as sweat evaporates it lowers the body temperature sweating to reduce hyperthermia vascular changes autonomic
138
red or pink skin; Smooth muscle in blood vessels of the skin relax/open, allow more blood to enter the skin
vasodilation
139
Contraction of arrector pili to trap air and make insulation layer; and smooth muscle in blood vessels of the skin to reduce blood flow and keep heat in sensory reception
vasoconstriction
140
ABCDE’s of Melanoma
A- Asymmetry B – uneven borders (melanoma) or smooth (benign) C – color (like brown, tan or black) D – diameter (larger than 1/4 inch) E - evolution (changing in size, shape, elevation, color or new symptom)
141
squamous outer most layer with dead/keratinized cells also called the horny layer and innermost layer is the stratum germinativum
epidermis
142
where cells are still dividing (mitosis) and there are melanocytes (produce the color in the skin)
stratum germinativum
143
dense connective tissue - collagenous and elastin fibers
dermis
144
what is contained in the dermis?
Blood vessels—pink/blushing from dilation, blue (cyanosis) from lack of oxygen Nerves Lymph Smooth muscle Sweat glands Hair follicles Sebaceous glands
145
aka subcutaneous fatty tissue (adipose) attaches dermis to muscle or bone and is considered the superficial fascia
hypodermis
146
where do hypodermic needle injections occur?
hypodermis
147
give examples of accessory structures of the skin
hair shaft is visible root in the epidermis hair follicle in epidermis and dermis arrector pili muscles - involuntary, autonomic nervous system activation goose bumps nails modification of leathery epidermal cells with hard keratin lunula - crescent at proximal end of each nail (white free end) air mixed with keratin cuticle is a layer of epidermis extending over the nail glands
148
what are the glands of the skin?
sebaceous, sweat, ceruminous
149
what are the purpose of sebaceous glands
oil lubrication for glossy and pliable skin and shiny hair
150
what is the purpose of sweat glands
to cool and secrete minimal waste most abundant in hands and feet
151
or sweat and heat regulation
eccrine sg
152
scent/odor (in armpits and genitalia)
appocrine sg
153
has sodium chloride (salty) - urea, uric acid, ammonia, other organic substances
sweat
154
what is the function of the ceruminous gland
modified apocrine sweat glands (has contributions from sebaceous glands) lubricates and protects the ear canal
155
how does cerumen protect the ear canal
Only in the dermis of the external auditory canals Cerumen traps foreign material like dust and pathogens Continuously produced and migrates out of canal
156
what is the purpose of skin receptors
purpose is to sense the external environment touch, pressure, vibration, temp, pain
157
vibration
pacinian corpuscle
158
touch
meissner corpuscle merkel endings
159
pressure
ruffini ending
160
touch/movement of hair
hair receptors
161
pain, temperature, itch, touch
free nerve endings
162
what are the 6 prominent types of mechanoreceptors
Encapsulated—Pacinian corpuscle, Meissner corpuscle, Ruffini ending Nonecapsulated –Hair receptors, Merkel endings, free nerve endings
163
what are our special senses?
Hearing (audition) & Balance Vision Olfaction Taste (gustatory sensations)
164
cells that detect stimuli and produce receptor potentials
sensory receptors
165
what are inner hair cells?
specialized mechanoreceptors
166
Mechanical displacement
mechanoreceptors
167
Temperature change
thermoreceptors
168
Pain –Tissue damage
nociceptors
169
Chemicals
chemoreceptors
170
light
Photoreceptors
171
Receptor distribution in the skin in not uniform—why?
some areas are more densely innervated than others like lips and fingertips as opposed to the back test by two point discrimination minimum distance by which two stimuli can be separated and still perceived as two stimuli
172
sensory area of skin that is going into specific spinal segment of nerves
dermatome
173
C2 Derm
occiput
174
C3 Derm
scalp around ear, pinna & other craniofacial including scalp around the ear, pinna, lateral cheek over angle of the jaw, submental region and lateral and anterior aspects of upper neck
175
C4 Derm
posterior neck and upper shoulder
176
C6, C7, C8: hand derm
C6: thumb C7: index and middle fingers C8: ring and little fingers
177
T1 Derm
upper thorax and anterior surface of upper extremity
178
T4 Derm
nipple zone
179
T5 derm
inferior angle of scapula f
180
T10 Derm
umbilical zone
181
L4 Derm
lateral thigh, anterior surface of knee, and medial leg, great toe
182
L5 derm
middle three toes, sole of foot, and great toe
183
S1 Derm
back of leg, little toe, heel and lateral foot
184
S2 Derm
genitalia and back of thigh
185
A muscular segment; one of the zones into which the muscles of the trunk, especially in fishes, are divided
myotomes
186
partial paralysis or weakness
paresis
187
can occur when upper motor neurons are damaged like in a stroke results if all roots innervating a particular muscle are destroyed
paralysis
188
Will spinal cord lesions affect control of bladder and bowels?
YES because they are controlled and innervated by low spinal cord segments (S2, S3, S4)
189
connective tissues that separate muscles
sclerotomes
190
what is Waardenburg
genetic and congenital mutation in changes of the melanocytes this changes pigmentation in skin, hair and eyes pale eyes/different colors, white patch of hair/early grey patches, patches of white or dark on skin can have moderate to profound HL and balance issues
191
red patches, thick, scaly, can bleed when scraped hyperactive stratum germinativum
psoriasis
192
uncontrolled growth in epidermal layer human papillomavirus
warts
193
herpes simplex virus fluid filled blisters
cold sores
194
Staphylococcus aureus bacteria, small blisters, highly contagious (face and can spread)
impetigo
195
staph infection of hair follicle or gland with pus
furuncle/boil
196
localized edema in epidermis red/pale and itchy elevated
urticaria/hives
197
what are external ear canal conditions
external otitis bacterial or fungal swimmers ear bacterial otomycosis - fungal nectrotizing (malignant) external otitis
198
what are features of the skin of the ear canal
cerumen glands hair angled to protect outer layer of ™ same as skin tissue epithelial migration
199
what is proprioception
respond to changes in position of the body or its parts
200
where are receptors
In the skin Muscles Joints And viscera (organs of the digestive, respiratory, urogenital and endocrine systems—and the spleen, the heart and the great vessles—the internal organs)—these might be specifically classified as visceral sensory instead of somatosensory
201
Detect muscle length
muscle spindles
202
detect muscle tension
golgi tendon organs
203
Respond to joint position and movement
joint receptors
204
how proprioception related to as and vs?
how we keep our balance
205
what is Resting membrane potential
high sodium outside the cell and high potassium concentration inside the cell, approximately -70 millivolts inside the cell
206
what is the sodium potassium pump
counterbalances this leakage (At rest Na+ leaks into the cell and K+ leaks out) moving 3 Na+ out and 2 K+ in (3:2 ratio) Na+/K+ ATPase pump—active/uses energy Maintains and re-establishes the resting membrane potential (balance necessary)
207
describe a receptor potential
Local and graded Amplitude modulated (more volt change for a larger stimulus, etc.) Carry info about location and nature of stimulus By the type of receptor, location and where it projects to in the CNS Intensity coded by amplitude of the receptor potential, the threshold of the receptors and how many (whole hand touching vs one finger) Duration coded by the duration of the receptor potential and Slowly adapting—continue to respond but at a diminished level throughout the duration of the stimulus Rapidly adapting- signal the beginning and end of a stimulus Combinations of receptors cover the full range of information that needs to be encoded