Exam 1 Questions

Question 1

A clinical study performed with subjects who developed septicemia. It’s observed that there is wide-scale activation of macrophages when there’s a septicemia, particularly when blood cultures are positive for Enterobacteriaceae. Which of the following substance most likely have the greatest effectiveness in eliciting this macrophage activation?

Answer 1

Lipopolysaccharide

Question 2

A macrophage helps defend the body against pathogens by?

Answer 2

Phagocytosis

Question 3

In an experiment, the actions of inflammatory cells are studied in response to bacterial pneumonia. It’s observed that when the pneumonia begins to resolve, the alveoli are filled with macrophages actively phagocytizing debris from the inflammatory process. These macrophages are most likely to be derived from which of the following cells circulating in the bloodstream?

Answer 3

Monocytes

Question 4

Which is not a leukocyte?

Answer 4

Erythrocyte

Question 5

Which immune cell is responsible for the quickest release of histamine that causes the red itchy wells associated with allergies

Answer 5

Mast cell

Question 6

A study conducted is assess means for T cell activation in an immune response. It’s observed that there are multiple clones of naive T cells. Each clone is programmed to respond to a different antigen. How are these antigens most likely presented to the naive T cells?

Answer 6

Macrophages display peptides with MHC molecules

Question 7

A study is conducted of T cell receptors. It’s show that a T cell surface component must be present in order for signal transduction and activation of the T cell to occur from antigen encounter. Which of the following proteins is most likely to form this required surface comment?

Answer 7

CD3

Question 8

In an experiment, the result of T cell interaction with peptides complexed with MHC2 molecules is studied. When B cells are added, it’s observed that immunoglobulin synthesis in the B cell increases. Which of the following cells
Surface markers is most likely to be present on these (T helper cells)

Answer 8

CD4

Question 9

Which of these cell types can play a primary role in attacking and killing cancer cells?

Answer 9

Cytotoxic T cell

Question 10

Upon activation of specific B cell by an antigen, it differentiates into a cell whole main role is to produce antibody. What are these antibody-producing ‘factories’ known as?

Answer 10

Plasma Cells

Question 11

Helper T cells are usually

Answer 11

CD4+