Exam 1: Hard Tissue and Cartilage Flashcards
One of the most dynamic and metabolically active tissues
Bone
Bone remains active throughout
Life
Bone is highly ___ which means it has excellent capacity for ____
Vascular; self-repair
Bone can also alter its properties/configuration to respond/adapt to
Changes in mechanical demand
Examples of changes in bone properties
Bone density changes due to disuse
Shape changes during fracture/surgical healing
Cortical bone is ____ whereas trabecular bone is ____
Stiffer/brittle; tougher
Bone is anisotropic which means that it exhibits distinct mechanical properties when
Loaded along various axes
Because its structure differs in transverse and longitudinal directions
Cortical bone can withstand greater stress in ___ > ___ > ___
Compression > tension > shear
Cortical bone can tolerate _____ > ____
Longitudinal loads > transverse loads
Bone fractures can be produced by
Single load — exceeds ultimate strength
Repeated lower-magnitude loads
Wolff’s Law
Bone has ability to remodel to meet mechanical demands placed on it
Bone remodeling is due to _____ NOT ____
Responses to forces; degeneration
Bone is ____ when not needed
Resorbed
Load/demand can be placed on bone by _____ leading to _____
Muscle activity or gravity; bone deposition
Cartilage is essentially _____
Nonvascular
Cartilage is composed of
Collagen, chondrocytes and ground substance
3 types of cartilage
Articular
Hyaline
Fibrocartilage
Articular cartilage is ____ and subject to ______
Viscoelastic; creep and relaxation
During joint articulation, forces at the joint surface vary from
0 to >10x body weight
Cartilage is nearly ____ which is unlike any man-made material
Frictionless
Interfacial wear is caused by either
Adhesion or abrasion
Fatigue wear is caused by
Repetition of high loads over short period
Repetition of low loads over extended period
Articular cartilage has only limited capacity for
Repair and regeneration
The magnitude of stress sustained by articular cartilage is determined by
Total load and how it is distributed over articular surface contact area
Any intense stress concentration will play primary role in
Tissue degeneration
How many IVD in an adult
23 (numeric name for segment above)
Discs constitute ____% of entire height of vertebral column
20-33%
3 parts of the disc
Nucleus pulposus
Annulus fibrosus
Cartilaginous end plates
Disc to VB ratio
Height of IVD compared to height of VB
Greater disc:VB ratio means
Greater spinal segmental mobility
Disc:VB ratio is greatest in ____ spine
Cervical (2:5)
Disc:VB ratio is least in the ____ spine
Thoracic (1:5)
Disc:VB ratio in lumbar spine
1:3
Nucleus pulposus is a _____ with fine fibrous strands
Mucoprotein gel
Nucleus pulposus is ____% water
70-90%
- 90 at birth
- 80 at 20yrs
- 70 old age
Bigger discs have ___ capacity to change size
More, because of creep
Lumbar nuclei fill ___% of total disc area and are located ____
30-50%; located more posterior