Essentials for bacterial regulation Flashcards
a(n) ___ is a stretch of DNA consisting of an operator, a promoter and genes for a related set of proteins, usually making up and entire metabolic pathway
operon!!
the ____ is/are arranged sequentially after the promoter
genes of an operon
a(n) ____ is a specific nucleotide sequence in DNA that binds RNA plymerase, positioning it to start transcribing RNA at the apporiate place
promoter
a(n) ____ codes for a protein, such as a repressor, that controls the transcription of another gene or group of genes
regulatroy genes
regulatroy proteins bind to the ____ to control expression of the operon
operator!!
a(n) ____ is a protein that inhibits gene transcription. in prokaryotes, this protein binds to the DNA in or near the promoter
repressor
a(n) ____ is a specific small molecule that binds to a bacterial regulatory protein and changes its shape so that it cannot bind to an operator, thus switching an operon on
inducer
whats the difference between positive and negative regulation?
positive regulation requires an activator binded to the promoter to initiate transcription, no activator means no transcription
negative regulation requires a repressor attached to the promoter to disable transcription. no repressor and transcription will be initiated