EPSPs and IPSPs Flashcards
1
Q
Why do myelinated axons propagate APs much faster than unmyelinated axons?
A
- the myelin sheath acts as an electrical insulator allowing for the AP to travel exponentially faster
- fewer AP cycles due to less channels and myelin transmitting electrical current
2
Q
When the AP reaches threshold, are the depolarizing forces larger or smaller than the stabilizing forces?
A
Larger
3
Q
What is the charge at threshold?
A
- -55mV
4
Q
How do IPSPs and EPSPs affect AP propagation or reaching threshold?
A
IPSPs and EPSPs sum together at the axon hillock
AP propagated if threshold was reached
5
Q
Modes of action of general anesthetics
A
- Block action potential propagation
- Block NT release from vesicles
- Degrade NT in synaptic cleft
- Block action of NT on postsynaptic membrane
- Hyperpolarize postsynaptic membrane
6
Q
Why are injectable anesthetics preferred to inhaled ones in certain situations?
A
- controlled dosage
- rapid onset
- predictable depth of anesthesia
