Epithelial Tissue Flashcards
Is epithelia vascular or avascular
Avascular
Tight junction location and proteins involved
Encircle cells near the most apical surface
Occludins, claudins
Adherins
Lateral adhesions involving cadherins that interact with actin
Desmosomes
Lateral adhesions involving cadherins that interact with intermediate filaments
Hemidesmosomes
Basal adhesions involving integrins and intermediate filaments that anchor to basal lamina
Bacteria that cause food poisoning target what
Tight junctions in the intestin
Pemphigus vulgaris
Autoimmune disease leading to abnormal desmosome function, reduces cell-cell adhesion and causes blisters of oral mucosa
Microvilli
Cytosolic processes with an actin core
Specialized for absorption, increase surface area 20-30x
Celiac disease
Loss of microvilli on absorptive cells in SI
Stereocilia
Microtubule structure with actin core
Increase surface area
Longer and less mobile than microvilli
Found in epididymis and hair cells of inner ear
Cilia structure, 3 types of cilia
Highly motile structure containing arrays of microtubules
3 types- motile, primary and nodal
Motile- propel substances across the tissue
Primary- immotile, function as chemosensors/mechanosensors/osmosensors
Nodal- embryonic, have role in L/R axis determination
Simple squamous location/function
Lining of blood and lymphatic vessels (endothelium), lining of serous membranes (mesothelium), lining alveoli in lungs, loop of henle
Exchange, barrier, lubrication
Simple cuboidal location/function
Kidney tubules, glands & associated ducts, terminal bronchioles, covering of he ovary
Absorption, barrier, secretion
Simple columnar location/function
Auditory tubes, uterus, oviducts, stomach, SI/LI, gallbladder
Absorption/secretion
Pseudostratified columnar ciliated location function
Lining of nasal cavity, pharynx, trachea, bronchi
Absorption/secretion, debris and particulate movement
Urothelium location/function
Urinary bladder, ureters, urethra
Barrier, distensible property
Non keratinized stratified squamous location/function
Oral cavity, portions of pharynx, esophagus, anus, vagina, urethra, cornea
Barrier and protection
Keratinized stratified squamous location/function
Epidermis of skin
Barrier and protection
Stratified cuboidal location/function
Sweat glands/ducts, ovarian follicles, salivary gland ducts
Barrier and passageway
Serous membrane examples
Peritoneum, pericardium, pleura
Unicellular gland example
Goblet cells- line respiratory tract and intestines
Exocrine gland
Multicellular glands comprised of secretory cells grouped as an acinus
Parotid glands are composed of
Serous acini
Sublingual glands are composed of
Mucous acini
Submandibular glands are composed of
Serous, mucous and seromucous acini
Merocrine vs holocrine vs apocrine
Merocrine- secretion is delivered in membrane bound vesicles to apical surface & undergo exocytosis
Holocrine- Secretion accumulates, apoptosis occurs, secretory products and debris released
Apocrine- Release of apical portion of cell