Epi, Surveillance, and Outbreaks Flashcards
study of the frequency, distribution, cause, and control of disease in populations- forms the basis of all health-related studies. Provides the background for interventions to reduce transmission of infecting organisms, reduce the number of healthcare ass infections, and protect hc providers from infection
epidemiology
Main components of epi definition
frequency
distribution
cause
control
Ds of epi
Distribution
Determinants
Deterrents
How we describe determinants
Person
Place
Time
epi triangle
Host
Agent
Env
As one variable changes, there is a concomitant or resultant change in the quantity or quality of another variable
Association
3 types of associations
- artifactual (spurious)
- Indirect or noncausal
- causal
This type of association may be caused by errors in study design or analysis, bias, errors in analysis, or failure to control for confounding variables
Artificial or spurious association
this type of association may be caused by mixing of effects between the exposure, disease, and confounding variable that may be associated with the exposure and independently affect the outcome of interest
Indirect or noncausal
This type of association occurs when evidence indicates that one factor is clearly shown to increase the probability of the occurrence of a disease
Causal
The stronger the relation between a risk factor and the effect, the less likely it is that the relation is due to a third or extraneous factor
Strength of assocition
Multiple studies in a range of settings report similar results
Consistency
Ideally, the effect has only one cause
Specificity
the purported cause should be present before the effect occurs
temporality
A dose-response relation between the risk factor and the effect
Biological gradient
there should be a rational the theoretical basis explaining how or why the risk factor led to the effect
Biological plausabiity
The association should not conflict with known facts
Coherence
Is there any supportive research based on experiment; if preventative action is taken, does the effect dissipate?
Experimental evidence
A previously accepted phenomenon in one area can be applied to another
Analogy
- strength of association
- consistency
- specificity
- temporality
- biological gradient
- biological plausibility
- coherence
- experimental evidence
- analogy
Bradford Hill’s Criteria for Causation
Level of prevention with the goal to complete prevention of diseases before any manifestation of that disease occurs
Primary
Early dx and treatment and preventing further deterioration by intervention as early in the disease course as possible
secondary
Reducing complications
Tertiary
Examples secondary prevention
Screening
skin testing for TB
Mammograms