Endocrine System Flashcards

1
Q

Endocrine glands in the CNS area

A

Hypothalamus, pituitary, pineal gland

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2
Q

3 Places steroid hormones are produced by

A

Gonads (testes / ovaries)
Adrenal Cortex
Kidneys

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3
Q

What is direct cell communication

A

Is surface membrane to adjacent surface membrane, exchange of ions and small molecules

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4
Q

What is paracrine cell communication

A

Signalling through spread of extracellular fluid between cells of a single tissue

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5
Q

What is synaptic communication

A

Neurones release neurotransmitters at a synapse

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6
Q

What is endocrine communication

A

Uses hormones released into blood to coordinate cellular activities in distant tissues

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7
Q

In what hormones are receptors outside cell membrane

A

Amino acid based

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8
Q

In what hormones are receptors in cell

A

Steroid, are lipid soluble

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9
Q

What releases the thyroid stimulating hormone, follicle stimulating hormone and luteinising hormone

A

anterior Pituitary gland

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10
Q

What does the thyroid gland produce

A

Thyroxine

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11
Q

Function of parathyroid glands

A

Secrete parathyroid hormone when plasma levels of Ca2+ drop

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12
Q

Function of adrenal androgens

A

Promote muscle mass, blood cell formation and libido

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13
Q

Function of aldosterone

A

Supports level of Na+, when Na+ drops aldosterone is secreted and causes Na+ to be reasborbed in kidneys in exchange for K+ regultion of blood pressure

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14
Q

Where is the enzyme renin released from

A

Juxtaglomerular apparatus

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15
Q

Why is renin released

A

In response to decreased blood pressure or decreased plasma osmolarity

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16
Q

What is atrial natriuerectic factor

A

a hormone secreted by the heart when blood pressure rises which inhibits renin-angiotensin system

17
Q

What effect does natriueretic factor have on aldosterone

A

Inhibits the release of aldosterone

18
Q

What does the Adrenal medulla produce

A

Adrenaline & noradrenaline (epinephrine and norepinehrine)

19
Q

What do alpha cells produce

A

Glucagon

20
Q

What do beta cells produce

A

Insulin

21
Q

Function of glucagon

A

Glycogenolysis & Gluconeogenesis

22
Q

Function of insulin

A

Causes enhanced membrane transport of glucose into body cells

23
Q

What effect does insulin have on blood sugar

A

Lowers it

24
Q

Type 1 vs Type 2 Diabetes

A

Type 1 - no insulin activity resulting in increased blood glucose
Type 2 - Inadequate amount of insulin or problem with insulin receptors

25
Q

What is hyperinsulinism

A

Excessive excretion of insulin = hypoglycemia

26
Q

What hormone do the kidneys produce

A

Erythropoeitin - signals red bone marrow to increase production of RBC’s
Calcitrol and Renin

27
Q

What do the pineal glands produce and function

A

Melotonin - circadian cycles

28
Q

What hormone do the atria of the heart produce

A

Atrial Natriuretic factor

29
Q

What hormones does the thymus produce

A

Thymopoietins and Thymosins (stimulate development of antibodies in response to infection)

30
Q

Function of gastrin

A

Stimulate secretion of gastric acid, pepsinogen, intrinsic factor and secretin

31
Q

Reason for modern prevalence of T2DM

A

Enviromental and physical behavioural factors such as diet and physical inactivity