Endocrine: Pancreas, Gonads Flashcards

1
Q

Where is the pancreas located?

A

Long, flat, along the duodenum

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2
Q

True or False: Pancreas only has exocrine function

A

False - Endocrine and Exocrine

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3
Q

Endocrine portion of the pancreas is organized into thousands of tiny clumps of cells called ____________ ___________

A

pancreatic islets / islets of langerhans (scattered throughout the organ)

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4
Q

What are the 3 main endocrine cells of the pancreatic islets?

A

Alpha
Beta
Delta

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5
Q

What do alpha cells produce?

A

Glucagon

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6
Q

What do beta cells produce?

A

insulin

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7
Q

What do delta cells produce?

A

somatostatin

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8
Q

What role does insulin play?

A

Lowers blood glucose levels
(causes glucose, amino acids, and fatty acids in blood to be absorbed into body cells)

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9
Q

What role does glucagon play?

A

stimulates liver cells to convert glycogen to glucose; stimulates glycogenesis

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10
Q

What role does somatostatin play?

A

Inhibits the secretion of insulin and glucagon, GH, and diminishes the activity of GI tract

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11
Q

Disease from insulin deficiency

A

Diabetes Mellitus

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12
Q

What is the exocrine function of the pancreas?

A

Produces digestive enzymes

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13
Q

True or False: It is just as detrimental to have a glucagon deficiency as insulin

A

False - there are other hormones that have a hyperglycemic effect to supplement

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14
Q

The gonads are the reproductive organs - the _________ in the male and the ___________ in the female

A

Testes; ovaries

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15
Q

What is produced in the gonads?

A

Reproductive cells and important hormones

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16
Q

Clumps of endocrine cells that produce androgens

A

Interstitial cells

17
Q

What is the principal androgen that interstitial cells produce?

A

Testosterone

18
Q

Where is sperm produced?

A

seminiferous tubules

19
Q

True or False: The ovaries produce reproductive cells and hormones continuously

A

False - They do so in cycles

20
Q

What are the main hormone groups produced in the ovary?

A

Estrogens
Progestins

21
Q

What is a third hormone produced in the ovary late in pregnancy?

A

Relaxin

22
Q

Which estrogens are produced in the ovary?

A

Estradiol
Estrone

23
Q

What role does estrogen play in ovulation?

A
  • Follicle cells produce and release estrogens
  • Follicle grows
  • Estrogen production increases
  • FSH decreases, LH increases
  • LH peaks when follicle is fully mature
  • Ovulation occurs
24
Q

Where are progestins produced?

A

Corpus Luteum

25
Q

What is the principal progestin produced?

A

Progesterone

26
Q

How does pregnancy affect progestin levels?

A

If pregnant = corpus luteum produces progesterone
If not pregnant = lack of hormone causes corpus luteum to shrink and disappear

27
Q

What role does Relaxin have in parturition?

A

Causes ligaments between bones surrounding birth canal to soften and relax in preparation