Endocrine/Hormonal/Reproduction Drugs Flashcards
What are the clinical uses for Oxytocin?
augment the force of uterine contractions during delivery (dystocia), aid in delivery of placenta, induce milk letdown
What are the uses for Prostaglandins?
promote uterine contractions so can induce parturition or abortion
What are the uses for corticosteroids?
mimic natural rise in corticosteroids by the fetus as the time for delivery draws near and thus could induce parturition
What are the uses for Melatonin?
Alopecia in dogs, improve breeding/ovulation in sheep and goats
What are the uses for Metergoline?
treats false pregnancy in dogs
What are the uses for Neutersol?
can be injected directly into testicles of puppies to cause permanent sterility; does NOT eliminate testosterone
What is Feliway?
feline facial hormone; stopping or preventing urinary markings by cats, comforts the cat in unknown stressful environments
What is D.A.P.?
dog appeasing pheromone; calms dogs during stressing situations
Hypothyroidism occurs in _______.
dogs
Hyperthyroidism occurs in ______.
cats
What drug is used to treat hypothyroidism?
Levothyroxine Sodium (T4)
What is Liothyronine Sodium (T3)?
treatment of hypothyroidism if not responsive to Levothyroxine
What are thyroid-stimulating hormones?
used as an aid to diagnose hypothyroidism
What drug is used to treat hyperthyroidism?
Methimazole
What is a form of Methimazole?
Felimazole
What is Radioactive Iodine (I-131)?
treats hyperthyroidism
How is Radioactive Iodine used?
given IV and absorbed and destroys over-productive thyroid tissue
What are the uses for Mitotane?
used to treat PDH
What is a form of Mitotane?
Lysodren
What does Trilostane inhibit?
inhibits adrenal steroid synthesis
What are the uses for Trilostane?
used to treat Cushing’s (Hyperadrenocorticism)
What is a form of Trilostane?
Vetoryl
What is Addison’s (hypoadrenocorticism)?
low/no cortisol production (steroid production)
What are some treatments for Addison’s?
Prednisone, Deoxycorticosterone pivalate (DOCP), Fludrocortisone
What type of diabetes is insulin dependent?
Type I Diabetes
What type of diabetes is non-insulin dependent?
Type II Diabetes
What type of diabetes is common in dogs?
Type I
What type of diabetes is common is cats?
Type II
What are some clinical signs of diabetes?
PU/PD, weight loss
What are some forms of regular insulin?
Humulin R, Novolin R
What types of insulins are short acting?
regular insulin
What are short acting insulins used for?
emergency treatment of DKA
What are intermediate acting insulins used for?
long-term management of diabetes
What are some forms of intermediate acting insulins?
Humulin-N, Novolin-N, Prozinc, Vetsulin
What types of insulin are long acting?
Glargine (cats), Detemir
What are long acting insulins used for?
long term treatment of diabetes
What are some forms of Glargine and Detemir?
Lantus and Levemir
What are the clinical uses for Gondorelin (GnRH)?
treats cystic ovaries in dairy cattle
What are the clinical uses for Chorionic Gonadotropin (hCG)?
cystic ovaries in dairy cattle, infertility caused by low testosterone
What are the clinical uses for Gonadotropins?
superovulation, out of season breeding
What is Estrogen used for in cattle?
persistent carpus luteum, expel purulent material from uterus, promote weight gain
What is Estrogen used for in dogs?
control urinary incontinence
What is Estrogen used for in horses?
induction of estrus in non-breeding season
What are some forms of Estrogen?
Estradiol (Incurin), Diethylstilbestrol (DES)
What are some side effects of Estrogen?
severe anemia
Is Estrogen used in males or females?
females
Are Androgens mainly used in males or females?
males
What are some forms of Androgens?
Methyltestosterone, Testosterone Cypionate, Testosterone Enanthate, Testosterone Propionate, Milberone
What are some uses for Androgens?
urinary incontinence in male dogs
Which Androgen can be used in femlaes?
Milberone
What are some uses for Milberone?
prevention of estrus in dogs, treatment of false pregnancy
What are some side effects of Milberone?
clitoral hypertrophy, vulvovaginitis, increased body odor
What are some clinical uses for Progestins in dogs?
control estrus, false pregnancies, prevent vaginal hyperplasia, treat severe galactorrhea, control unacceptable male behavior
What are some clinical uses for Progestin in cats?
dermatologic and behavioral problems and suppression of estrus
What are some side effects of Progestins?
hyperglycemia
What drugs fall under the Progestin group?
Megestrol Acetate, Medroxyprogesterone Acetate (MPA), Altrenogest, Norgestomet, Melengestrol Acetate
What are some uses for Medroxyprogesterone Acetate (MPA)?
treatment of behavioral problems, treatment of certain dermatologic conditions
What are some forms of Medroxyprogesterone Acetate (MPA)?
Depo-Provera
What is Altrenogest?
oral progestin for horses and swine to suppress estrus in mares and gilts
What is Norgestomet?
used to synchronize estrus in cattle (synchro-mate B)
What are some uses for Dinoprost Tromethamine?
abortion producing agent in dogs/cats
What are some forms of Dinoprost Tromethamine?
Lutalyse
What are some side effects of Dinoprost Tromethamine?
sweating, abdominal pain, dyspnea and panting, tachycardia
What are some uses for Cloprostenol Sodium in cattle?
treatment of mummified fetuses, termination of pregnancy, estrus synchronization
What is Bovine Somatotropin?
growth hormone
What does Bovine Somatotropin do?
increases growth rate in bovine, increases milk production