endocrine dx Flashcards
1
Q
SIADH
A
- overproduction/oversecretion of ADH
- excess ADH=reabsorption of water into circulation=low Na
2
Q
causes of SIADH
A
- drugs
- head trauma
- Ca
- metabolic dz
- CVA
- SLE
- hypothyroidism
- lung infx
3
Q
s/s of SIADH
A
- serum hypo osmolarity
- dilutional low Na, low Chl,
- fluid retention, weight gain, cerebral edema
- increased intravascular volume
- concentrated urine
- normal renal function
- muscle cramps and weakness
- fatigue
- thirst
- low UOP
- sz, coma
4
Q
diagnostic studies for SIADH
A
- urine osmolality
- serum osmolality less than 280
- low Na
- SG greater than 1.005
5
Q
tx for SIADH if Na > 125 mEq/L
A
- fluid restriction 800-1000mL/24 hours
- hypertonic saline solution 3-5%
- diuretics
6
Q
tx for SIADH if Na less than 120
A
- fluid restriction 500mL/24 hour
- demeclocycline, lithium
- vasopressin
- ICU or monitored bed
7
Q
positioning for SIADH
A
- flat
- 10 degree HOB elevation
8
Q
diet for SIADH
A
supplement Na, K
9
Q
diabetes insipidus
A
- deficiency of production of ADH
- decreased renal response to ADH
10
Q
central diabetes insipidus
A
- most common
- neurogenic
- occurs when there is an organic lesion that interferes with ADH synthesis or release
- secondary to intracranial surgery or head trauma
11
Q
nephrogenic diabetes insipidus
A
adequate but decreased response to ADH by the kidney
12
Q
psychogenic diabetes insipidus
A
- dispogenic
- associated with excessive water intake
13
Q
causes of diabetes insipidus
A
- head trauma
- tumors
- surgical ablation or irradiation of pituitary
- infx of CNS
- drugs
14
Q
acute phase of diabetes insipidus
A
- abrupt onset of polyuria
- 1-5L/hour
15
Q
interphase of diabetes insipidus
A
- urine volume normalizes
- decrease in UOP, but still high