autoimmune dx Flashcards
1
Q
rheumatoid arthritis (RA)
A
- chronic, systemic autoimmune dz
- inflammation of connective tissue in the synovial joints
- periods of remission and exacerbation
- can occur at any time, incidence increases with age
2
Q
causes of RA
A
- autoimmune
- *genetics
- smoking
3
Q
diagnosing RA
A
- H/P
- +rheumatoid factor
- ESR and CRP=active inflammation
- xray: for later disease
4
Q
RA classification criteria
A
- morning stiffness that lasts at least an hour
- polyarthritis
- arthritis in the wrist, or finger joints
- symmetrical arthritis
- positive rheumatoid factor
- radiological abnormalities of hands or wrist
5
Q
nonspecific s/s of RA
A
- fatigue
- anorexia
- wt loss
- generalized stiffness
6
Q
specific articular s/s of RA
A
- pain
- stiffness
- limited motion
- s/s inflammation
7
Q
extraarticular s/s of RA
A
- rheumatoid nodules
- Sjogren’s syndrome
- Felty syndrome
- pleural effusion, pericarditis, pericardial effusion, cardiomyopathy
- cataracts
- depression
8
Q
rheumatoid nodules
A
firm, non tender granuloma type masses locate over joints
9
Q
Sjogren’s syndrome
A
- diminished lacrimal and salivary gland secretion
- photosensitivity
10
Q
Felty syndrome
A
- splenomegaly
- leukopenia
11
Q
tx for Sjogren’s syndrome
A
- goal: to relieve symptoms
- dry eyes: artificial tears, eye lubricating ointments, or cyclosporine liquid
- dry mouth: H2O, chewing sugarless gum
12
Q
tx for RA
A
- rest
- joint protection
- heat/cold application
13
Q
systemic lupus erythematosus (SLE)
A
- multisystem inflammatory autoimmune dz
- chronic, unpredictable course
- periods of exacerbation and remission
14
Q
causes of SLE
A
- **unknown
- genetics
- hormones
- environment: sun exposure, infx
- drug reactions
15
Q
diagnosing SLE
A
- ANA, anti ENA
- complement system levels
- electrolytes
- renal function
- liver enzymes
- CBC