Endocrine and Urinary

Question 1

Hyperadrenocorticism

Answer 1

 Cushing’s Disease
 Most common in dogs
 Caused by excessive production of glucocorticoids by the adrenal gland

Question 2

Etiology of Cushing’s

Answer 2

Pituitary gland tumor
Adrenal gland tumor
Adrenal gland hyperplasia

Question 3

Clinical Findings Cushing’s

Answer 3

Most common in middle-age to older dogs
Clinical signs
-slowly progressive
-polyphagia, PU/PD, abdominal enlargement, exercise intolerance, alopecia, thin epidermis

Question 4

Diagnosis of Cushing’s

Answer 4

Clinical signs
CBC
Blood chemistry
Urinalysis
Cortisol, ACTH stimulation test, dexamethasone suppression test

Question 5

Treatment of Cushing’s

Answer 5

Medical- Mitotane (Lysodren, Ketoconazole, Selegilene (Anipryl), Trilostane
-Surgery