Early development (dave's notes) Flashcards

1
Q

What are the stages of development from day 1 to day 6?

A

Zygote -> morula -> blastocyst -> implantation

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2
Q

What is the outer layer of the developing cell mass? What does this become?

A

Trophoblast, becomes placenta

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3
Q

What is the inner layer of the developing cell mass?

A

The inner cell mass -> amnion and yolk sac

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4
Q

What divides the amnion and yolk sac divided by? What three things does this give rise to?

A

The embryonic plate. This gives rise to ectoderm, primary mesoderm, and endoderm

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5
Q

What grows from ectoderm to endoderm?

A

The notochord is an axial rod of cells growing from ectoderm to endoderm

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6
Q

Where does the neural tube develop? What does this later form?

A

The neural tube develops on the ectodermal surface, which is later to form the brain and spinal cord

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7
Q

What does the neural crest develop from? What does this form?

A

Cells at the edges (of what?) become isolated and develop the neural crest which becomes posterior root ganglia, ganglia of cranial nerves and autonomic ganglia

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8
Q

How does mesoderm lie?

A

In three longitudinal strips

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9
Q

What does the mesodermal strip nearest the midline become?

A

Segments into mesodermal somites which

  1. produce sclerotome, which surrounds the neural tube and notochord -> becomes vertebrae and dura mater
  2. myotome producing muscles of the body wall
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10
Q

What does the intermediate strip of mesoderm produce?

A

The intermediate cell mass and becomes segmented

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11
Q

What does the lateral side of the intermediate cell mass become?

A

The lateral side develops the pronephros, mesonephros, and metanephros

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12
Q

What does the medial side of the intermediate cell mass become?

A

The gonad and cortex of the suprarenal gland

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13
Q

Other than the lateral and medial side, what develops from the intermediate cell mass?

A

The lateral plate which is unsegmented

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14
Q

Why does the embryo begin to curl up?

A

From increased dorsal growth relative to ventral growth

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15
Q

What happens to the lateral plate?

A

The lateral plage curls around enclosing the yolk sac.

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16
Q

What happens to the mesoderm?

A

The mesoderm splits into two layers enclosing the coelom

17
Q

What is the inner layer of mesoderm called? What does it become? What does it contain? What does this become?

A

The inner layer of mesoderm is the splanctopleure (ANS) which encloses the yolk sac (outside umbilical cord and vitellointestinal duct, inside GI)

18
Q

What is the outer layer of mesoderm called? What does this become?

A

The outer layer is the somatopleure (somatic nerves), visceral layer supplied if at all by autonomic nerves

19
Q

Where do limb buds grow from?

A

The lateral plate

20
Q

What does the septum transverses consist of?

A

Mesodermal mass lying on the cranial aspect of the coelomic cavity. This develops into the pericardial membranes and part of the diaphragm, invaded by muscles from the cervical myotome.

21
Q

What does the developing liver invade?

A

The caudal septum transversum

22
Q

What happens to the septum transvedsum later in development?

A

It descends taking the heart with it.

23
Q

What is the mouth pit called? Where does it develop?

A

The somatodeum forms a dimple between the forebrain capsule and pericardium