E4: pit

Question 1

syndrome of inappropriate ADH (SIADH)

Answer 1

excessive amounts of ADH resulting in H2O imbalance

(excess ADH=too much ANTI=retention of tooo much H2O

Question 2

cause of SIADH

Answer 2

• trauma
• medications
• tumors producing ADH
• infected lung tissue producing ADH
• post-pituitary surgery
• feedback inhibition

Question 3

pathway of SAIDH

Answer 3

hypothal–> post. pit–> increased ADH secretion–> increased H20 reabsorption–> fluid retention

Question 4

clinical mani of SAIDH RT retention

Answer 4

• hyponatremia (dilutional)
• HTN
• edema
• urine is low concentrated output
• increased urine sodium

Question 5

main loop with SAIDH

Answer 5

increased H20 reabsorption inhibits post pit

Question 6

what if the entire pituitary gland has problems

Answer 6

if the mother gland aint happy– no one happy

Question 7

panhypopituitarism

Answer 7

deficiency of one or more hormones of the pituitary (usually the ant. pit)

Question 8

decreased Gh

Answer 8

dwarfism

Question 9

decreased ACTH

Answer 9

addisons

Question 10

decreased TSH

Answer 10

hypothyrodidm

Question 11

decreased LH and FSH

Answer 11

sexual and reproductive disorders

Question 12

decreased ADH

Answer 12

diabetes insipidus

Question 13

panhyperpituitarism

Answer 13

oversecretion of one or more of the hormones of the pituitary (usually the ant pit)

Question 14

increased GH

Answer 14

giantism/acromegaly

Question 15

increased ACTH

Answer 15

cushings disease

Question 16

increased TSH

Answer 16

hyperthyroidism

Question 17

increased FSH and LH

Answer 17

sexual/repro problems

Question 18

increased ADH

Answer 18

SIADH

Question 19

increased prolactin

Answer 19

Galactorrhea (excessive breast milk)

Question 20

metabolic syndrome

Answer 20

a combination of medical conditions:

• insulin resistance (T2 DM)
• HTN
• central obesity
• high lipid/cholesterol

Question 21

patho of metabolic syndrome

Answer 21

• Not known
• genetic role (obesity, lack of exercise)
• systemic inflammation
• -increased CRP
• -increased fibrinogen