E3: acute adult neuro Flashcards
intracranial adaptive capacity
the ability of any of the 3 components of the brain to adapt to changes in size
increased intracranial pressure
increased pressure inside cranium, can lead to brain cell injury and death
brain cells are
voracious consumers of o2 and glucose
if the brain cells are deprived of o2 and glucose, what happens
irreversible damage in minutes
brain tissue %
80%
blood %
10%
CSF %
10%
cerebral perfusion pressure
required to perfuse brain cells
normal CPP
60-90 mm/hg
how much of the cardiac output does the brain require
15-20%
formula for CPP
CCP=MAP minus ICP
normal ICP
5-15 mm/Hg
etiology in increased ICP
- swelling of brain
- increased blood volume
- increased CSF
early clinical mani of increased ICP in LOC
confusion
restlessness
lethargy
late clinical mani of increased ICP in loc
loss of consciousness
early clinical mani of increased icp in pupil
subtle, sluggish reaction
late clinical mani of increased ICP in pupils
dialating, fixed
Cushing triad
late signs of VERY HIGH increased ICP
- widening pulse pressure (S increases, d decreases)
- bradycardia
- respirations decrease and are irregular
other signs of increased icp
- severe headache
- projectile vomiting
- seizures
- papilledema (edema of optic disc/nerve)
- altered motor function
(extremity strength and movement,
abnormal posturing
-decorticate
-decerebrate)
decorticate
abnormal flexion in increased ICP
decerebrate
abnormal extension in increased ICP
herniation of the brain
- sever increased ICP
- shifting of brain from one compartment to another
- places pressure on cerebral blood vessels and vital centers (medulla)
- death