drugs used in labour

Question 1

oxytocin

Answer 1

stimulates cervical ripening and uterine contractions

Question 2

infusions of oxytocin are used to

Answer 2

induce labour
progress labour
improve freq + strength of contractions
prevent/treat PPH

Question 3

ergometrine

Answer 3

stimulates smooth muscle contraction - uterus + blood vessels

useful for delivering placenta + reduce PPH

Question 4

ergometrine side effects

Answer 4

htn
diarrhoea
vomiting
angina

Question 5

when to avoid erometrine

Answer 5

PET

Question 6

syntometrine

Answer 6

combo drug of oxytocin and ergometrine

used for prevention or treatment of PPH

Question 7

prostaglandins

Answer 7

stimulate uterine contractions

cervical ripening

Question 8

Mifepristone

Answer 8

anti-progestogen
halts pregnancy and stimulates cervical ripening

used for aborptions and IUFD

Question 9

Carboprost

Answer 9

synthetic prostaglandin analogue

stimulated uterine contraction

IM Injectin in PPH where ergometrin + oxytocin been inadequate

Question 10

tranexamic acid

Answer 10

antifibrinolytic medication

binds to plasminogen and prevents it becoming plasmin

–> helps prevent breakdown of clots

Question 11

when is tranexamic acid used

Answer 11

prevent and treat PPH