downs syndrome screening Flashcards
1
Q
CUBS
A
combined USS and blood test screening
2
Q
when is CUBS done
A
11-14wks
3
Q
CUBS - what
A
USS nuchal translucency
blood tests: Beta HCG and PAPP
4
Q
B-HCG - what indicates higher risk
A
higher result
5
Q
pregnancy associated plasma protein - what indicated greater risk
A
lower result
6
Q
triple test
A
materal blood tests
14-20wks
7
Q
triple test - what done
A
B-HCG
alpha-feto protein
serum oestriol
8
Q
alpha-feto protein - what result indicates greater risk
A
lower result
9
Q
Serum oestriol - what result indicates higher risk
A
lower result
10
Q
invasive testing
A
sample of fetal cells to perform karyotyping to give definitive answer
11
Q
Chorionic villus sampling
A
USS biopsy of placental tissue
<15wks
12
Q
amniocentesis
A
USS aspiration of amniotic fluid
13
Q
NIPT
A
blood test from mother - will contain fragments of fetal DNA
