Drugs for Blood Cell Deficiency (Part 02)

Question 1

A Drug for Iron Deficiency Anemia

Answer 1

Iron (Fe)

Question 2

Total Quantity of Iron in the Body

Answer 2

4 g to 5 g

Question 3

It is the transporter of oxygen in the blood.

Answer 3

Hemoglobin

Question 4

It is the transporter of iron.

Answer 4

Transferrin

Question 5

An iron storage protein.

Answer 5

Ferritin

Question 6

This is the iron and oxygen binding protein found in the skeletal muscle tissue.

Answer 6

Myoglobin

Question 7

A metallo-protein (contains copper and iron) final, enzyme of the electron transport system found in the mitochondria.

Answer 7

Cytochrome Oxidase

Question 8

Two (2) Iron Preparations

Answer 8

1. Oral Iron Preparations
2. Parenteral Iron Preparations

Question 9

Drug/s under Oral Iron Preparations

Answer 9

1. Ferrous Sulfate
2. Ferrous Gluconate
3. Ferrous Fumarate

Question 10

325 mg to 65 mg Elemental Iron

Answer 10

Ferrous Sulfate

Question 11

325 mg to 37 mg Elemental Iron

Answer 11

Ferrous Gluconate

Question 12

325 mg to 106 mg Elemental Iron

Answer 12

Ferrous Fumarate

Question 13

Drug/s under Parenteral Iron Preparations

Answer 13

1. Iron Dextran
2. Iron Sorbitol

Question 14

It should be reserved for patients with documented iron deficiency that unable to tolerate or absorb iron. With extensive chronic blood loss who cannot be maintained with oral iron alone.

Answer 14

Parenteral Iron Preparations

Question 15

Two (2) Treatments of Iron Toxicity

Answer 15

1. Acute Iron Toxicity
2. Chronic Iron Toxicity

Question 16

Drug/s for Megaloblastic Anemia and Pernicious Anemia

Answer 16

1. Vitamin B9 (Folic Acid)
2. Vitamin B12 (Cobalamin)

Question 17

Deficiency of either of these vitamins results in impaired production and abnormal maturation of RBCs giving rise the characteristic blood and bone marrow suppression.

Answer 17

Vitamin B9 and Vitamin B12

Question 18

Five (5) Brand Names of Vitamin B9 (Folic Acid)

Answer 18

1. Folvite
2. Folart
3. Folicard
4. Hemarate FA
5. Fortifer FA

Question 19

It is converted to tetrahydrofolate by the action of dihydrofolate reductase.

Answer 19

Vitamin B9 (Folic Acid)

Question 20

ROA of Vitamin B9 (Folic Acid)

Answer 20

Oral Folic Acid

Question 21

Two (2) Brand Names of Vitamin B12 (Cobalamin)

Answer 21

1. Polynerv
2. Neurobion

Question 22

Two (2) Available Forms of Vitamin B12 (Cobalamin)

Answer 22

1. Cyanocobalamin
2. Hydroxocobalamin

Question 23

The active form of B12 is now prescribed for the treatment of vitamin B12 deficiency.

Answer 23

Mecobalamin (Methycobal)

Question 24

__________ is absorbed from the GIT in the presence of intrinsic factor of castle.

Answer 24

Cobalamin

Question 25

ROA of Vitamin B12 (Cobalamin)

Answer 25

Parenteral

Question 26

Drug/s for CKD-Induced Anemia

Answer 26

1. Epoetin Alfa (Epogen, Procrit) 2. Darbepoetin (Aranesp)

Question 27

__________ is used for anemia associated with renal failure and sometimes effective for patients with other forms of anemia.

Answer 27

Erythropoietin

Question 28

A Long-Acting Version of Erythropoietin

Answer 28

Darbepoetin (Aranesp)

Question 29

A Drug for Sickle Cell Anemia

Answer 29

Hydroxyurea

Question 30

The drug apparently increases fetal hemoglobin levels, thus diluting the abnormal hemoglobin S (HbS).

Answer 30

Hydroxyurea

Question 31

A Drug for Megakaryocytes

Answer 31

Oprelvekin (Neumega)

Question 32

The recombinant form of an endogenous cytokine.

Answer 32

Oprelvekin (Neumega)

Question 33

Two (2) Thrombopoietin Receptor Agonists

Answer 33

1. Romiplostim 2. Eltrombopag

Question 34

A thrombopoietin receptor agonist with novel peptide structure.

Answer 34

Romiplostim

Question 35

An oral agonist of the thrombopoietin receptor.

Answer 35

Eltrombopag

Question 36

It stimulate the production and function of neutrophils. GM-CSF also stimulates the production of other myeloid and megakaryocyte progenitors.

Answer 36

Granulocyte Colony - Stimulating Factor

Question 37

Used to accelerate the recovery of neutrophils after cancer chemotherapy.

Answer 37

Granulocyte Colony - Stimulating Factor

Question 38

Drug/s under Granulocyte Colony - Stimulating Factor

Answer 38

1. Filgrastim 2. Sargramostim 3. Pegfilgrastim 4. Lenograstim

Question 39

The covalent conjugation product of filgrastim and the form of polyethylene glycol.

Answer 39

Pegfilgrastim

Question 40

It is used widely in Europe, is the glycosylated form of recombinant G-CSF.

Answer 40

Lenograstim