Drugs Flashcards
Describe the mechanism and range of vancomycin
- Can only act on gram positive as unable to penetrate gram negative cell wall.
- Inhibits cell wall synthesis.
- Only given parenterally
- Use for MRSA
Describe the mechanism and range of gentamicin
- Concentration dependent bactericidal.
- Useful for treatment of serious gram negative
- Inhibits protein synthesis
- use to treat unknown gram negative bacteria
Describe the mechanism and range of Nitrofurantoin
- only use in urinary tract infection
- inhibitor of nucleic acid synthesis
What disease is Saquinavir prescribed to combat?
- Used in HIV therapy
What drug would be used in herpes simplex virus (HSV) and varicella zoster virus (VZV)?
Aciclovir
What drug should be used only in a urinary tract infection?
Nitrofuratoin
What drug should be used in serious fungal infection therapy?
Nystatin
How is nystatin perscribed?
Topically or in oral suspension
What drug would you perscribe to combat B-lactamase producing staph.aureus
Flucloxacillin
What drug would you prescribe for a serious systemic fungal infection (hint: can also be administered via IV)
Amphotericin B
What drug would be the best choice for serious pneumococcal and meningococcal and strep pyogenes infections, as well as most other gram positive infections
Benzylpenicillin
What is the mechanism for Ciprofloxacin + Fluoroquinolone
Inhibit protein synthesis
What drug can B-lactamase resistance be combatted with?
Co-amoxiclav
