Diuretics - 6

Question 0

Mannitol

Answer 0

Osmotic diuretic

Question 1

Acetazolamide

Answer 1

Carbonic anhydrase inhibitor (diuretic)

• makes bicarbonate and H ions for exchange with Na
• inhibitor causes indirect blocking of Na/H antiporter, blocking reabsorption

Question 2

Furosemide

Answer 2

Loop diuretic - most potent type

• less Na reabsorption
• NB high ceiling diuretic

Question 3

Bumetanide

Answer 3

Loop diuretic - most potent type

• decreases Na reabsorption
• don’t use with heart or renal failure or pulmonary oedema

Question 4

Thiazide

Answer 4

Distal tubule diuretic

• inhibits Na/Cl symporter
• can cause hyperglycaemia and erectile dysfunction

Question 5

Indapamide

Answer 5

Distal tubule diuretic

• inhibits Na/Cl symporter
• can cause hyperglycaemia and erectile dysfunction

Question 6

Hydrochlorothiazide

Answer 6

Distal tubule diuretic
-inhibits Na/Cl symporter
- can cause hyperglycaemia and erectile dysfunction
NB low ceiling diuretic

Question 7

Spironolactone

Answer 7

Competitive aldosterone antagonist (diuretic)

• K-sparing
• gynecomastia and hyperkalemia