Diseases of the kidney and the excretory system in ruminants Flashcards
Structure
• Renal diseases
o Non-purulentrenaldiseases ▪ Acute nephrosis
▪ Renal amyloidosis
▪ Non purulent nephritis
o Purulentrenaldiseases
▪ Purulent nephritis
▪ Contagious bovine pyelonephritis
• Urolithiasis
Non-purulent renal diseases
- Acute nephrosis
- Renal amyloidosis
- Non purulent nephritis
Non-purulent renal diseases
Common characteristics
- Subclinical course, usually not diagnosed in vivo
- Symptoms of underlying disease are dominant (common)
- Clinical signs of renal disease (rare)
Non-purulent renal diseases
- Acute nephrosis
Cause:
- Intoxication
- Pb/As/Cu toxicosis
- hemoglobin nephrosis
- monensin
- tannins (foliage of oak trees and acorns)
- unidenfied toxin of Amaranthus retroflexus
- ochratoxin
Non-purulent renal diseases
- Acute nephrosis
Characteristics
- Rarely diagnosed clinically (no obvious signs)
* Urine: proteinuria, renal epithelial cells/cylinders (casts)
Non-purulent renal diseases
- Renal amyloidosis
Cause
➢ Chronic inflammatory (purulent) diseases of other organs immunological processes abnormal antigen- antibody reaction
➢ hyperglobulinemia amyloid protein deposition (causing acute kideny failure)
➢ (systemic disease)
Non-purulent renal diseases
- Renal amyloidosis
Sequela
- Renal enlargement (kidney can be evaluated -> rectal palpation -> size, lobulated, pressure for presence of pain)
- Weight loss
- Nephrotic syndrome: massive proteinuria + edema formation
- Uremia: halitosis, uremic stomatitis, diarrhoea
Non-purulent renal diseases
- Renal amyloidosis
Differential diagnosis
- perform rectal examination, urinalysis!
* traumatic pericarditis, paratuberculosis
Non-purulent renal diseases
- Non-purulent nephritis
(= glomerulonephritis, interstitial nephritis)
• primary disease or component of systemic diseases
• immun-complex formation (glomerulonephritis)
• infectious diseases (interstitial nephritis, e.g. leptospirosis)
Non-purulent renal diseases
- Non-purulent nephritis
Characteristics
- Rarely diagnosed clinically (no obvious signs)
- Can be detected by ultrasound-guided biopsy if necessary
- Urine: proteinuria, renal epithelial cells/cylinders (casts)
Purulent renal diseases
- Purulent nephritis
2. Contagious bovine pyelonephritis
Purulent renal diseases
- Purulent nephritis
- (embolic nephritis) -> mostly
* (embolic suppurative nephritis or renal abscess)
Purulent renal diseases
- Purulent nephritis
Occurrence and etiology
bacterial (metastatic emboli), hematogenous route from
• valvular endocarditis
• suppurative lesions in uterus, udder, navel (umbilicus)
• septicemias in calves/ lambs
Purulent renal diseases
- Purulent nephritis
Characteristics
- rarely diagnosed clinically (no obvious signs)
- but: +/- rectal finding,
- urine: proteinuria, pyuria, (microsc.) hematuria, bacteruria
Purulent renal diseases
- Purulent nephritis
Treatment
antibiotics (sensitivity test; no nephrotoxic drugs)