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Clinical Pathology > Diseases of MSK 2 > Flashcards

Diseases of MSK 2 Flashcards

1
Q

Embryological origin of soft tissue

A

Mesoderm

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2
Q

What classifies as soft tissue

A

Nonepithelial extraskeletal structures exclusive of supportive tissue of organs and lymphoid/hematopoietic tissue

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3
Q

Fat tumours

A

Lipomas

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4
Q

Fibrous tissue tumours

A

Fibromas

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5
Q

Smooth muscle tumours

A

Leiomyomas

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6
Q

Blood vessel tumours

A

Haemangiomas

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7
Q

Lymphatic tumours

A

Lymphangiomas

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8
Q

Peripheral nerve tumours

A

Neuroma

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9
Q

Malignant soft tissue tumours

A

Sarcoma

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10
Q

Are soft tissue tumours usually benign or malignant?

A

Benign

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11
Q

Do soft tissue tumours often involve the lymph nodes?

A

No

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12
Q

Where do soft tissue tumours spread to?

A

Liver and lung

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13
Q

How do you diagnose soft tissue tumours?

A

Ultrasound guided core biopsy
Wide excision
Cytogenetics
Molecular genetics

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14
Q

Syndrome associated with neurofibroma

A

Neurofibromatosis type 1

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15
Q

SYndrome associated with fibromatosis

A

Gardner syndrome

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16
Q

Syndrome associated with myxoma, melanotic schwannoma

A

Carney syndrome

17
Q

Synrome associated with cystic hygroma

A

Turner syndrome

18
Q

Benign bone tumour

A

Osteoma and osteobalstoma

19
Q

Benign cartilage tumours

A

Chondroma

20
Q

Mixed bone and cartilage tumours

A

Osteochondromas

21
Q

Commonest malignant bone tumour

A

Osteosarcoma

22
Q

Typical age group and location of osteosarcoma

A

Young

Knee

23
Q

Which cancers metastasise to the bone

A

Thyroid, prostate, kidney, breast, GI tract etc

24
Q

Complex multisystem disease ,predominantly cutaneous. Female predominance

A

sytemic lupus erythematosis

25
Q

What type of rash is associated with SLE?

A

Butterfly- bridge of nose and cheeks

26
Q

How does SLE affect different organs in the body?

A

Skin
Cardiac- cardiomegaly endocarditis
CNS-convulsions, hemiplegia
Rnal-nephrotic syndrome and glomerulonephritis

Clinical Pathology (53 decks)

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