Diseases of MSK 2 Flashcards
Embryological origin of soft tissue
Mesoderm
What classifies as soft tissue
Nonepithelial extraskeletal structures exclusive of supportive tissue of organs and lymphoid/hematopoietic tissue
Fat tumours
Lipomas
Fibrous tissue tumours
Fibromas
Smooth muscle tumours
Leiomyomas
Blood vessel tumours
Haemangiomas
Lymphatic tumours
Lymphangiomas
Peripheral nerve tumours
Neuroma
Malignant soft tissue tumours
Sarcoma
Are soft tissue tumours usually benign or malignant?
Benign
Do soft tissue tumours often involve the lymph nodes?
No
Where do soft tissue tumours spread to?
Liver and lung
How do you diagnose soft tissue tumours?
Ultrasound guided core biopsy
Wide excision
Cytogenetics
Molecular genetics
Syndrome associated with neurofibroma
Neurofibromatosis type 1
SYndrome associated with fibromatosis
Gardner syndrome
Syndrome associated with myxoma, melanotic schwannoma
Carney syndrome
Synrome associated with cystic hygroma
Turner syndrome
Benign bone tumour
Osteoma and osteobalstoma
Benign cartilage tumours
Chondroma
Mixed bone and cartilage tumours
Osteochondromas
Commonest malignant bone tumour
Osteosarcoma
Typical age group and location of osteosarcoma
Young
Knee
Which cancers metastasise to the bone
Thyroid, prostate, kidney, breast, GI tract etc
Complex multisystem disease ,predominantly cutaneous. Female predominance
sytemic lupus erythematosis
What type of rash is associated with SLE?
Butterfly- bridge of nose and cheeks
How does SLE affect different organs in the body?
Skin
Cardiac- cardiomegaly endocarditis
CNS-convulsions, hemiplegia
Rnal-nephrotic syndrome and glomerulonephritis